Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo

Annals of the Rheumatic Diseases

Volumn 75, Issue 6, 2016, Pages 1228-1235

  Eldridge, Suzanne ^a   Nalesso, Giovanna ^a   Ismail, Habib ^a   Vicente Greco, Karin ^b   Kabouridis, Panos ^c   Ramachandran, Manoj ^d   Niemeier, Andreas ^e   Herz, Joachim ^f   Pitzalis, Costantino ^a   Perretti, Mauro ^a   Dell'Accio, Francesco ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b NPIMR Y3 ^*  (United Kingdom)

^c THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^d ROYAL LONDON HOSPITAL   (United Kingdom)

^e UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGRIN; ALPHA DYSTROGLYCAN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 4; UNCLASSIFIED DRUG; DYSTROGLYCAN; LOW DENSITY LIPOPROTEIN RECEPTOR; LRP4 PROTEIN, HUMAN; LRP4 PROTEIN, MOUSE; MESSENGER RNA; SMALL INTERFERING RNA; SOX9 PROTEIN, MOUSE; TRANSCRIPTION FACTOR SOX9;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; DISEASE ACTIVITY; EXTRACELLULAR MATRIX; HOMEOSTASIS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; ANIMAL; ARTICULAR CARTILAGE; BIOSYNTHESIS; BONE DEVELOPMENT; CELL CULTURE; CHONDROCYTE; CHONDROGENESIS; DBA MOUSE; DOWN REGULATION; DRUG EFFECTS; EXPERIMENTAL ARTHRITIS; GENE SILENCING; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; UPREGULATION;

AGRIN; ANIMALS; ARTHRITIS, EXPERIMENTAL; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; DOWN-REGULATION; DYSTROGLYCANS; GENE KNOCKDOWN TECHNIQUES; HOMEOSTASIS; HUMANS; LDL-RECEPTOR RELATED PROTEINS; MALE; MICE, INBRED DBA; MICE, KNOCKOUT; OSTEOARTHRITIS; OSTEOGENESIS; RECEPTORS, LDL; RNA, MESSENGER; RNA, SMALL INTERFERING; SOX9 TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84940214372     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2015-207316     Document Type: Article

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