Human CHAC1 protein degrades glutathione, and mRNA induction is regulated by the transcription factors ATF4 and ATF3 and a bipartite ATF/CRE regulatory element

Journal of Biological Chemistry

Volumn 290, Issue 25, 2015, Pages 15878-15891

  Crawford, Rebecca R ^a   Prescott, Eugenia T ^a   Sylvester, Charity F ^a   Higdon, Ashlee N ^a   Shan, Jixiu ^b   Kilberg, Michael S ^b   Mungrue, Imran N ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CELL MEMBRANES; NUCLEIC ACIDS; PEPTIDES; PHOSPHOLIPIDS; PROTEINS; TRANSCRIPTION; TRANSCRIPTION FACTORS; YEAST;

ACTIVATING TRANSCRIPTION FACTOR; CCAAT/ENHANCER-BINDING PROTEINS; DELETION ANALYSIS; ENDOPLASMIC RETICULUM STRESS PATHWAY; LUCIFERASE REPORTER SYSTEM; OXIDIZED PHOSPHOLIPIDS; PROMOTER UPSTREAM; REGULATORY ELEMENTS;

CLONE CELLS;

ACTIVATING TRANSCRIPTION FACTOR 3; ACTIVATING TRANSCRIPTION FACTOR 4; CCAAT ENHANCER BINDING PROTEIN BETA; GLUTATHIONE; HEAT SHOCK PROTEIN; MESSENGER RNA; PROTEIN CHAC1; UNCLASSIFIED DRUG; ATF3 PROTEIN, HUMAN; ATF4 PROTEIN, HUMAN; CCAAT ENHANCER BINDING PROTEIN; GAMMA GLUTAMYLCYCLOTRANSFERASE; GGCT PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; EMBRYO; ENDOPLASMIC RETICULUM STRESS; GENE DELETION; GENE MUTATION; GENE OVEREXPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; MODIFIER GENE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; MOUSE; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

ACTIVATING TRANSCRIPTION FACTOR 3; ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; BASE SEQUENCE; CCAAT-ENHANCER-BINDING PROTEINS; ENDOPLASMIC RETICULUM STRESS; GAMMA-GLUTAMYLCYCLOTRANSFERASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE; HEK293 CELLS; HUMANS; MICE; OXIDATIVE STRESS; RESPONSE ELEMENTS; RNA, MESSENGER; SEQUENCE DELETION;

EID: 84940213218     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.635144     Document Type: Article

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