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Volumn 213, Issue , 2016, Pages 15-19

Uric acid and xanthine oxidase in heart failure - Emerging data and therapeutic implications

Author keywords

Cachexia; Ischemic stroke; MCAO model; Muscle; Sarcopenia

Indexed keywords

ALLOPURINOL; BENZBROMARONE; FEBUXOSTAT; OXIPURINOL; OXYGEN RADICAL; PROBENECID; RECOMBINANT URATE OXIDASE; URIC ACID; XANTHINE OXIDASE; REACTIVE OXYGEN METABOLITE;

EID: 84940069192     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.08.089     Document Type: Article
Times cited : (63)

References (76)
  • 1
    • 84908294192 scopus 로고    scopus 로고
    • Metabolic impairment in heart failure. The myocardial and systemic perspective
    • W. Doehner, M. Frenneaux, and S.D. Anker Metabolic impairment in heart failure. The myocardial and systemic perspective J. Am. Coll. Cardiol. 64 2014 1388 1400
    • (2014) J. Am. Coll. Cardiol. , vol.64 , pp. 1388-1400
    • Doehner, W.1    Frenneaux, M.2    Anker, S.D.3
  • 3
    • 84888073074 scopus 로고    scopus 로고
    • J Relation of respiratory muscle strength, cachexia and survival in severe chronic heart failure
    • D. Habedank, F.J. Meyer, R. Hetzer, S.D. Anker, and R. Ewert J Relation of respiratory muscle strength, cachexia and survival in severe chronic heart failure Cachex. Sarcopenia Muscle 4 2013 277 285
    • (2013) Cachex. Sarcopenia Muscle , vol.4 , pp. 277-285
    • Habedank, D.1    Meyer, F.J.2    Hetzer, R.3    Anker, S.D.4    Ewert, R.5
  • 4
    • 0035040884 scopus 로고    scopus 로고
    • Uric acid in cachectic and non-cachectic patients with chronic heart failure: Relationship to leg vascular resistance
    • W. Doehner, M. Rauchhaus, V.G. Florea, and et al. Uric acid in cachectic and non-cachectic patients with chronic heart failure: relationship to leg vascular resistance Am. Heart J. 141 2001 792 799
    • (2001) Am. Heart J. , vol.141 , pp. 792-799
    • Doehner, W.1    Rauchhaus, M.2    Florea, V.G.3
  • 6
    • 0031723208 scopus 로고    scopus 로고
    • Uric acid in chronic heart failure: A measure of the anaerobic threshold
    • F. Leyva, T.P. Chua, S.D. Anker, and et al. Uric acid in chronic heart failure: a measure of the anaerobic threshold Metabolism 47 1998 1156 1159
    • (1998) Metabolism , vol.47 , pp. 1156-1159
    • Leyva, F.1    Chua, T.P.2    Anker, S.D.3
  • 7
    • 0031779935 scopus 로고    scopus 로고
    • The glycolytic pathway to coronary heart disease: A hypothesis
    • F. Leyva, C.S. Wingrove, I.F. Godsland, and et al. The glycolytic pathway to coronary heart disease: a hypothesis Metabolism 47 1998 657 662
    • (1998) Metabolism , vol.47 , pp. 657-662
    • Leyva, F.1    Wingrove, C.S.2    Godsland, I.F.3
  • 8
    • 0033520357 scopus 로고    scopus 로고
    • Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure
    • U.E. Ekelund, R.W. Harrison, O. Shokek, R.N. Thakkar, R.S. Tunin, H. Senzaki, D.A. Kass, E. Marban, and J.M. Hare Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure Circ. Res. 85 1999 437 445
    • (1999) Circ. Res. , vol.85 , pp. 437-445
    • Ekelund, U.E.1    Harrison, R.W.2    Shokek, O.3    Thakkar, R.N.4    Tunin, R.S.5    Senzaki, H.6    Kass, D.A.7    Marban, E.8    Hare, J.M.9
  • 10
    • 33748116331 scopus 로고    scopus 로고
    • The effect of xanthine oxidase inhibition upon ejection fraction in heart failure patients: La Plata Study
    • H.E. Cingolani, J.A. Plastino, E.M. Escudero, B. Mangal, J. Brown, and N.G. Pérez The effect of xanthine oxidase inhibition upon ejection fraction in heart failure patients: La Plata Study J. Card. Fail. 12 2006 491 498
    • (2006) J. Card. Fail. , vol.12 , pp. 491-498
    • Cingolani, H.E.1    Plastino, J.A.2    Escudero, E.M.3    Mangal, B.4    Brown, J.5    Pérez, N.G.6
  • 11
    • 84957582535 scopus 로고    scopus 로고
    • Serum uric acid is inversely proportional to estimated stroke volume and cardiac output in a large sample of pharmacologically untreated subjects: Data from the Brisighella Heart Study
    • A.F. Cicero, M. Rosticci, A. Parini, C. Baronio, S. D'Addato, and C. Borghi Serum uric acid is inversely proportional to estimated stroke volume and cardiac output in a large sample of pharmacologically untreated subjects: data from the Brisighella Heart Study Intern. Emerg. Med. 9 2014 655 660
    • (2014) Intern. Emerg. Med. , vol.9 , pp. 655-660
    • Cicero, A.F.1    Rosticci, M.2    Parini, A.3    Baronio, C.4    D'Addato, S.5    Borghi, C.6
  • 14
    • 20044381182 scopus 로고    scopus 로고
    • Allopurinol reduces B-type natriuretic peptide concentrations and haemoglobin but does not alter exercise capacity in chronic heart failure
    • A.D. Gavin, and A.D. Struthers Allopurinol reduces B-type natriuretic peptide concentrations and haemoglobin but does not alter exercise capacity in chronic heart failure Heart 91 2005 749 753
    • (2005) Heart , vol.91 , pp. 749-753
    • Gavin, A.D.1    Struthers, A.D.2
  • 15
    • 68949215869 scopus 로고    scopus 로고
    • Association between allopurinol and mortality in heart failure patients: A long-term follow-up study
    • L. Wei, T. Fahey, A.D. Struthers, and T.M. MacDonald Association between allopurinol and mortality in heart failure patients: a long-term follow-up study Int. J. Clin. Pract. 63 2009 1327 1333
    • (2009) Int. J. Clin. Pract. , vol.63 , pp. 1327-1333
    • Wei, L.1    Fahey, T.2    Struthers, A.D.3    MacDonald, T.M.4
  • 17
    • 33846379499 scopus 로고    scopus 로고
    • Hyperuricaemia predicts poor outcome in patients with mild to moderate chronic heart failure
    • E.A. Jankowska, B. Ponikowska, J. Majda, and et al. Hyperuricaemia predicts poor outcome in patients with mild to moderate chronic heart failure Int. J. Cardiol. 115 2007 151 155
    • (2007) Int. J. Cardiol. , vol.115 , pp. 151-155
    • Jankowska, E.A.1    Ponikowska, B.2    Majda, J.3
  • 18
    • 34147149642 scopus 로고    scopus 로고
    • Hyperuricaemia and long-term outcome after hospital discharge in acute heart failure patients
    • D.A. Pascual-Figal, J.A. Hurtado-Martínez, B. Redondo, and et al. Hyperuricaemia and long-term outcome after hospital discharge in acute heart failure patients Eur. J. Heart Fail. 9 2007 518 524
    • (2007) Eur. J. Heart Fail. , vol.9 , pp. 518-524
    • Pascual-Figal, D.A.1    Hurtado-Martínez, J.A.2    Redondo, B.3
  • 19
    • 60349118199 scopus 로고    scopus 로고
    • Hyperuricemia in acute heart failure. More than a simple spectator?
    • A.L. Alimonda, J. Núñez, E. Núñez, and et al. Hyperuricemia in acute heart failure. More than a simple spectator? Eur. J. Intern. Med. 20 2009 74 79
    • (2009) Eur. J. Intern. Med. , vol.20 , pp. 74-79
    • Alimonda, A.L.1    Núñez, J.2    Núñez, E.3
  • 20
    • 77955138299 scopus 로고    scopus 로고
    • Uric acid as prognostic marker in advanced nonischemic dilated cardiomyopathy: Comparison with N-terminal pro B-type natriuretic peptide level
    • H. Kim, H.W. Shin, J. Son, H.J. Yoon, H.S. Park, Y.K. Cho, C.D. Han, C.W. Nam, S.H. Hur, Y.N. Kim, and K.B. Kim Uric acid as prognostic marker in advanced nonischemic dilated cardiomyopathy: comparison with N-terminal pro B-type natriuretic peptide level Congest. Heart Fail. 16 2010 153 158
    • (2010) Congest. Heart Fail. , vol.16 , pp. 153-158
    • Kim, H.1    Shin, H.W.2    Son, J.3    Yoon, H.J.4    Park, H.S.5    Cho, Y.K.6    Han, C.D.7    Nam, C.W.8    Hur, S.H.9    Kim, Y.N.10    Kim, K.B.11
  • 23
    • 33645827323 scopus 로고    scopus 로고
    • The Seattle Heart Failure Model: Prediction of survival in heart failure
    • W.C. Levy, D. Mozaffarian, D.T. Linker, and et al. The Seattle Heart Failure Model: prediction of survival in heart failure Circulation 113 2006 1424 1433
    • (2006) Circulation , vol.113 , pp. 1424-1433
    • Levy, W.C.1    Mozaffarian, D.2    Linker, D.T.3
  • 26
    • 44649122196 scopus 로고    scopus 로고
    • OPT-CHF investigators. Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study
    • J.M. Hare, B. Mangal, J. Brown, and et al. OPT-CHF investigators. Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study J. Am. Coll. Cardiol. 51 2008 2301 2309
    • (2008) J. Am. Coll. Cardiol. , vol.51 , pp. 2301-2309
    • Hare, J.M.1    Mangal, B.2    Brown, J.3
  • 28
    • 0014410114 scopus 로고
    • The reduction of cytochrome c by milk xanthine oxidase
    • J.M. McCord, and I. Fridovich The reduction of cytochrome c by milk xanthine oxidase J. Biol. Chem. 243 1968 5753 5760
    • (1968) J. Biol. Chem. , vol.243 , pp. 5753-5760
    • McCord, J.M.1    Fridovich, I.2
  • 29
    • 0018886265 scopus 로고
    • Liver xanthine oxidase increase in mice in three pathological models. A possible defence mechanism
    • E. Tubaro, B. Lotti, G. Cavallo, C. Croce, and G. Borelli Liver xanthine oxidase increase in mice in three pathological models. A possible defence mechanism Biochem. Pharmacol. 29 1980 1939 1943
    • (1980) Biochem. Pharmacol. , vol.29 , pp. 1939-1943
    • Tubaro, E.1    Lotti, B.2    Cavallo, G.3    Croce, C.4    Borelli, G.5
  • 30
    • 84879205363 scopus 로고    scopus 로고
    • Large-scale isolation of human skeletal muscle satellite cells from post-mortem tissue and development of quantitative assays to evaluate modulators of myogenesis
    • I.C. Scott, W. Tomlinson, A. Walding, B. Isherwood, and I.G. Dougall Large-scale isolation of human skeletal muscle satellite cells from post-mortem tissue and development of quantitative assays to evaluate modulators of myogenesis J. Cachex. Sarcopenia Muscle 4 2013 157 169
    • (2013) J. Cachex. Sarcopenia Muscle , vol.4 , pp. 157-169
    • Scott, I.C.1    Tomlinson, W.2    Walding, A.3    Isherwood, B.4    Dougall, I.G.5
  • 31
    • 0035199068 scopus 로고    scopus 로고
    • Uric acid is closely linked to vascular nitric oxide activity. Evidence for mechanism of association with cardiovascular disease
    • A.J. Maxwell, and K.A. Bruinsma Uric acid is closely linked to vascular nitric oxide activity. Evidence for mechanism of association with cardiovascular disease J. Am. Coll. Cardiol. 38 2001 1850 1858
    • (2001) J. Am. Coll. Cardiol. , vol.38 , pp. 1850-1858
    • Maxwell, A.J.1    Bruinsma, K.A.2
  • 32
    • 0027585643 scopus 로고
    • Subcellular distribution of xanthine oxidase during cardiac ischemia and reperfusion: An immunocytochemical study
    • M. Ashraf, and Z.Q. Samra Subcellular distribution of xanthine oxidase during cardiac ischemia and reperfusion: an immunocytochemical study J. Submicrosc. Cytol. Pathol. 25 1993 193 201
    • (1993) J. Submicrosc. Cytol. Pathol. , vol.25 , pp. 193-201
    • Ashraf, M.1    Samra, Z.Q.2
  • 33
    • 34147186256 scopus 로고    scopus 로고
    • Uric acid as a prognostic marker in acute heart failure - New expectations from an old molecule
    • W. Doehner, S. von Haehling, and S.D. Anker Uric acid as a prognostic marker in acute heart failure - new expectations from an old molecule Eur. J. Heart Fail. 9 2007 437 439
    • (2007) Eur. J. Heart Fail. , vol.9 , pp. 437-439
    • Doehner, W.1    Von Haehling, S.2    Anker, S.D.3
  • 34
    • 0024354391 scopus 로고
    • Changes in xanthine oxidase activity in patients with circulatory failure
    • (Article in Russian)
    • Z.A. Bakhtiiarov Changes in xanthine oxidase activity in patients with circulatory failure Ter. Arkh. 61 1989 68 69 (Article in Russian)
    • (1989) Ter. Arkh. , vol.61 , pp. 68-69
    • Bakhtiiarov, Z.A.1
  • 35
    • 0037058827 scopus 로고    scopus 로고
    • Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: Role of xanthine-oxidase and extracellular superoxide dismutase
    • U. Landmesser, S. Spiekermann, S. Dikalov, H. Tatge, R. Wilke, C. Kohler, D.G. Harrison, B. Hornig, and H. Drexler Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase Circulation 106 2002 3073 3078
    • (2002) Circulation , vol.106 , pp. 3073-3078
    • Landmesser, U.1    Spiekermann, S.2    Dikalov, S.3    Tatge, H.4    Wilke, R.5    Kohler, C.6    Harrison, D.G.7    Hornig, B.8    Drexler, H.9
  • 36
    • 12344282055 scopus 로고    scopus 로고
    • Elevated plasma xanthine oxidase activity in chronic heart failure: Source of increased oxygen radical load and effect of allopurinol in a placebo controlled, double blinded treatment study
    • W. Doehner, M.T. Tarpey, D.V. Pavitt, A.P. Bolger, R. Wensel, S. von Haehling, D.A. Reaveley, and S.D. Anker Elevated plasma xanthine oxidase activity in chronic heart failure: source of increased oxygen radical load and effect of allopurinol in a placebo controlled, double blinded treatment study J. Am. Coll. Cardiol. 42 Suppl. 207A 2003
    • (2003) J. Am. Coll. Cardiol. , vol.42
    • Doehner, W.1    Tarpey, M.T.2    Pavitt, D.V.3    Bolger, A.P.4    Wensel, R.5    Von Haehling, S.6    Reaveley, D.A.7    Anker, S.D.8
  • 37
  • 38
    • 84874232148 scopus 로고    scopus 로고
    • Muscle wasting in patients with chronic heart failure: Results from the studies investigating co-morbidities aggravating heart failure (SICA-HF)
    • S. Fülster, M. Tacke, A. Sandek, N. Ebner, C. Tschöpe, W. Doehner, S.D. Anker, and S. von Haehling Muscle wasting in patients with chronic heart failure: results from the studies investigating co-morbidities aggravating heart failure (SICA-HF) Eur. Heart J. 34 2013 512 519
    • (2013) Eur. Heart J. , vol.34 , pp. 512-519
    • Fülster, S.1    Tacke, M.2    Sandek, A.3    Ebner, N.4    Tschöpe, C.5    Doehner, W.6    Anker, S.D.7    Von Haehling, S.8
  • 39
    • 84951557779 scopus 로고    scopus 로고
    • Prevalence, incidence, and clinical impact of sarcopenia: Facts, numbers, and epidemiology - Update 2014
    • J.E. Morley, S.D. Anker, and S. von Haehling Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology - update 2014 J. Cachex. Sarcopenia Muscle 5 2014 253 259
    • (2014) J. Cachex. Sarcopenia Muscle , vol.5 , pp. 253-259
    • Morley, J.E.1    Anker, S.D.2    Von Haehling, S.3
  • 40
    • 84951560065 scopus 로고    scopus 로고
    • Prevalence, incidence and clinical impact of cachexia: Facts and numbers - Update 2014
    • S. von Haehling, and S.D. Anker Prevalence, incidence and clinical impact of cachexia: facts and numbers - update 2014 J. Cachex. Sarcopenia Muscle 5 2014 261 263
    • (2014) J. Cachex. Sarcopenia Muscle , vol.5 , pp. 261-263
    • Von Haehling, S.1    Anker, S.D.2
  • 44
    • 80054069941 scopus 로고    scopus 로고
    • Xanthine oxidaseand uric acid in cardiovascular disease: Clinical impact and therapeutic options
    • W. Doehner, and U. Landmesser Xanthine oxidaseand uric acid in cardiovascular disease: clinical impact and therapeutic options Semin. Nephrol. 31 2011 433 440
    • (2011) Semin. Nephrol. , vol.31 , pp. 433-440
    • Doehner, W.1    Landmesser, U.2
  • 47
    • 0037024270 scopus 로고    scopus 로고
    • Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: Results from 2 placebo-controlled studies
    • W. Doehner, N. Schoene, M. Rauchhaus, F. Leyva-Leon, D.V. Pavitt, D.A. Reaveley, G. Schuler, A.J. Coats, S.D. Anker, and R. Hambrecht Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies Circulation 105 2002 2619 2624
    • (2002) Circulation , vol.105 , pp. 2619-2624
    • Doehner, W.1    Schoene, N.2    Rauchhaus, M.3    Leyva-Leon, F.4    Pavitt, D.V.5    Reaveley, D.A.6    Schuler, G.7    Coats, A.J.8    Anker, S.D.9    Hambrecht, R.10
  • 49
    • 0035814786 scopus 로고    scopus 로고
    • Allopurinol enhances the contractile response to dobutamine and exercise in dogs with pacing-induced heart failure
    • T. Ukai, C.P. Cheng, H. Tachibana, A. Igawa, Z.S. Zhang, H.J. Cheng, and W.C. Little Allopurinol enhances the contractile response to dobutamine and exercise in dogs with pacing-induced heart failure Circulation 103 2001 750 755
    • (2001) Circulation , vol.103 , pp. 750-755
    • Ukai, T.1    Cheng, C.P.2    Tachibana, H.3    Igawa, A.4    Zhang, Z.S.5    Cheng, H.J.6    Little, W.C.7
  • 52
    • 85028229806 scopus 로고    scopus 로고
    • Muscle wasting: An overview of recent developments in basic research
    • S. Palus, S. von Haehling, and J. Springer Muscle wasting: an overview of recent developments in basic research J. Cachex. Sarcopenia Muscle 5 2014 193 198
    • (2014) J. Cachex. Sarcopenia Muscle , vol.5 , pp. 193-198
    • Palus, S.1    Von Haehling, S.2    Springer, J.3
  • 54
    • 84951557346 scopus 로고    scopus 로고
    • Anamorelin HCl (ONO-7643), a novel ghrelin receptor agonist, for the treatment of cancer anorexia-cachexia syndrome: Preclinical profile
    • C. Pietra, Y. Takeda, N. Tazawa-Ogata, M. Minami, X. Yuanfeng, E.M. Duus, and R. Northrup Anamorelin HCl (ONO-7643), a novel ghrelin receptor agonist, for the treatment of cancer anorexia-cachexia syndrome: preclinical profile J. Cachex. Sarcopenia Muscle 5 2014 329 337
    • (2014) J. Cachex. Sarcopenia Muscle , vol.5 , pp. 329-337
    • Pietra, C.1    Takeda, Y.2    Tazawa-Ogata, N.3    Minami, M.4    Yuanfeng, X.5    Duus, E.M.6    Northrup, R.7
  • 57
    • 84896397419 scopus 로고    scopus 로고
    • Highlights from the 7th Cachexia Conference: Muscle wasting pathophysiological detection and novel treatment strategies
    • N. Ebner, L. Steinbeck, W. Doehner, S.D. Anker, and S. von Haehling Highlights from the 7th Cachexia Conference: muscle wasting pathophysiological detection and novel treatment strategies J. Cachex. Sarcopenia Muscle 5 2014 27 34
    • (2014) J. Cachex. Sarcopenia Muscle , vol.5 , pp. 27-34
    • Ebner, N.1    Steinbeck, L.2    Doehner, W.3    Anker, S.D.4    Von Haehling, S.5
  • 59
    • 84874550781 scopus 로고    scopus 로고
    • Nutrition impact symptoms in advanced cancer patients: Frequency and specific interventions, a case-control study
    • A. Omlin, D. Blum, J. Wierecky, S.R. Haile, F.D. Ottery, and F. Strasser Nutrition impact symptoms in advanced cancer patients: frequency and specific interventions, a case-control study J. Cachex. Sarcopenia Muscle 4 2013 55 61
    • (2013) J. Cachex. Sarcopenia Muscle , vol.4 , pp. 55-61
    • Omlin, A.1    Blum, D.2    Wierecky, J.3    Haile, S.R.4    Ottery, F.D.5    Strasser, F.6
  • 60
    • 84951557315 scopus 로고    scopus 로고
    • Rehabilitation nutrition for sarcopenia with disability: A combination of both rehabilitation and nutrition care management
    • H. Wakabayashi, and K. Sakuma Rehabilitation nutrition for sarcopenia with disability: a combination of both rehabilitation and nutrition care management J. Cachex. Sarcopenia Muscle 5 2014 269 277
    • (2014) J. Cachex. Sarcopenia Muscle , vol.5 , pp. 269-277
    • Wakabayashi, H.1    Sakuma, K.2
  • 61
    • 85027932398 scopus 로고    scopus 로고
    • Resistance exercise: An effective strategy to reverse muscle wasting in hemodialysis patients?
    • C.M. Rhee, and K. Kalantar-Zadeh Resistance exercise: an effective strategy to reverse muscle wasting in hemodialysis patients? J. Cachex. Sarcopenia Muscle 5 2014 177 180
    • (2014) J. Cachex. Sarcopenia Muscle , vol.5 , pp. 177-180
    • Rhee, C.M.1    Kalantar-Zadeh, K.2
  • 63
    • 33846446393 scopus 로고    scopus 로고
    • Uric acid in CHF: Marker or player in a metabolic disease?
    • W. Doehner, S. von Haehling, and S.D. Anker Uric acid in CHF: marker or player in a metabolic disease? Int. J. Cardiol. 115 2007 156 158
    • (2007) Int. J. Cardiol. , vol.115 , pp. 156-158
    • Doehner, W.1    Von Haehling, S.2    Anker, S.D.3
  • 65
    • 33845447368 scopus 로고    scopus 로고
    • High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid
    • J. George, E. Carr, J. Davies, J.J. Belch, and A. Struthers High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid Circulation 114 2006 2508 2516
    • (2006) Circulation , vol.114 , pp. 2508-2516
    • George, J.1    Carr, E.2    Davies, J.3    Belch, J.J.4    Struthers, A.5
  • 66
    • 35848962497 scopus 로고    scopus 로고
    • Lowering serum urate does not improve endothelial function in patients with type 2 diabetes
    • W.S. Waring, J.A. McKnight, D.J. Webb, and S.R. Maxwell Lowering serum urate does not improve endothelial function in patients with type 2 diabetes Diabetologia 50 2007 2572 2579
    • (2007) Diabetologia , vol.50 , pp. 2572-2579
    • Waring, W.S.1    McKnight, J.A.2    Webb, D.J.3    Maxwell, S.R.4
  • 67
    • 20044363683 scopus 로고    scopus 로고
    • Xanthine oxidase inhibition for chronic heart failure: Is allopurinol the next therapeutic advance in heart failure?
    • W. Doehner, and S.D. Anker Xanthine oxidase inhibition for chronic heart failure: is allopurinol the next therapeutic advance in heart failure? Heart 91 2005 707 709
    • (2005) Heart , vol.91 , pp. 707-709
    • Doehner, W.1    Anker, S.D.2
  • 69
    • 77953615298 scopus 로고    scopus 로고
    • Effect of high-dose allopurinol on exercise in patients with chronic stable angina: A randomised, placebo controlled crossover trial
    • A. Noman, D.S. Ang, S. Ogston, C.C. Lang, and A.D. Struthers Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial Lancet 375 2010 2161 2167
    • (2010) Lancet , vol.375 , pp. 2161-2167
    • Noman, A.1    Ang, D.S.2    Ogston, S.3    Lang, C.C.4    Struthers, A.D.5
  • 71
    • 84873582827 scopus 로고    scopus 로고
    • Efficacy and tolerability of febuxostat in hyperuricemic patients with or without gout: A systematic review and meta-analysis
    • P. Ye, S. Yang, W. Zhang, Q. Lv, Q. Cheng, M. Mei, T. Luo, L. Liu, S. Chen, and Q. Li Efficacy and tolerability of febuxostat in hyperuricemic patients with or without gout: a systematic review and meta-analysis Clin. Ther. 35 2013 180 189
    • (2013) Clin. Ther. , vol.35 , pp. 180-189
    • Ye, P.1    Yang, S.2    Zhang, W.3    Lv, Q.4    Cheng, Q.5    Mei, M.6    Luo, T.7    Liu, L.8    Chen, S.9    Li, Q.10
  • 72
    • 65849386648 scopus 로고    scopus 로고
    • Febuxostat: A new treatment for hyperuricaemia in gout
    • N.L. Edwards Febuxostat: a new treatment for hyperuricaemia in gout Rheumatology (Oxford) 48 Suppl. 2 2009 ii15 ii19
    • (2009) Rheumatology (Oxford) , vol.48 , pp. ii15-ii19
    • Edwards, N.L.1
  • 74
    • 84904264420 scopus 로고    scopus 로고
    • Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): A large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia
    • T.M. MacDonald, I. Ford, G. Nuki, I.S. Mackenzie, R. De Caterina, E. Findlay, J. Hallas, C.J. Hawkey, S. Ralston, M. Walters, J. Webster, J. McMurray, F. Perez Ruiz, and C.G. Jennings Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): a large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia BMJ Open 4 2014 e005354
    • (2014) BMJ Open , vol.4 , pp. e005354
    • MacDonald, T.M.1    Ford, I.2    Nuki, G.3    MacKenzie, I.S.4    De Caterina, R.5    Findlay, E.6    Hallas, J.7    Hawkey, C.J.8    Ralston, S.9    Walters, M.10    Webster, J.11    McMurray, J.12    Perez Ruiz, F.13    Jennings, C.G.14
  • 75
    • 84888070375 scopus 로고    scopus 로고
    • Disruption of pro-oxidant and antioxidant systems with elevated expression of the ubiquitin proteosome system in the cachectic heart muscle of nude mice
    • E.C. Hinch, M.J. Sullivan-Gunn, V.C. Vaughan, M.A. McGlynn, and P.A. Lewandowski Disruption of pro-oxidant and antioxidant systems with elevated expression of the ubiquitin proteosome system in the cachectic heart muscle of nude mice J. Cachex. Sarcopenia Muscle 4 2013 287 293
    • (2013) J. Cachex. Sarcopenia Muscle , vol.4 , pp. 287-293
    • Hinch, E.C.1    Sullivan-Gunn, M.J.2    Vaughan, V.C.3    McGlynn, M.A.4    Lewandowski, P.A.5


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