Impaired insulin sensitivity as an independent risk factor for mortality in patients with stable chronic heart failure

Journal of the American College of Cardiology

Volumn 46, Issue 6, 2005, Pages 1019-1026

  Doehner, Wolfram ^a,b   Rauchhaus, Mathias ^b   Ponikowski, Piotr ^c   Godsland, Ian F ^d   Von Haehling, Stephan ^a,b,c,d   Okonko, Darlington O ^a   Leyva, Francisco ^a,d   Proudler, Anthony J ^d   Coats, Andrew J S ^e   Anker, Stefan D ^a,b  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c MILITARY HOSPITAL   (Poland)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e University of Sydney   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIGITALIS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; GLUCOSE; INSULIN; WARFARIN;

ADULT; AGED; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DISEASE COURSE; DUAL ENERGY X RAY ABSORPTIOMETRY; FOLLOW UP; FUNCTIONAL ASSESSMENT; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAVENOUS GLUCOSE TOLERANCE TEST; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MINIMAL MODEL TECHNIQUE; MORTALITY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RISK ASSESSMENT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SURVIVAL RATE; SURVIVAL TIME; TECHNIQUE;

CHRONIC DISEASE; FOLLOW-UP STUDIES; HEART FAILURE, CONGESTIVE; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 24944519346     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2005.02.093     Document Type: Article

References (30)

1. J.W. Swan, S.D. Anker, C. Walton Insulin resistance in chronic heart failure relation to severity and etiology of heart failure J Am Coll Cardiol 30 1997 527 532
2. G. Paolisso, S. De Riu, G. Marrazzo, M. Verza, M. Varricchio, F. D'Onofrio Insulin resistance and hyperinsulinemia in patients with chronic congestive heart failure Metabolism 40 1991 972 977
3. J.W. Swan, C. Walton, I.F. Godsland, A.L. Clark, A.J.S. Coats, M.F. Oliver Insulin resistance in chronic heart failure Eur Heart J 15 1994 1528 1532
4. J. He, L.G. Ogden, L.A. Bazzano, S. Vupputuri, C. Loria, P.K. Whelton Risk factors for congestive heart failure in U.S. men and women NHANES I epidemiologic follow-up study Arch Intern Med 161 2001 996 1002
5. C. Iribarren, A.J. Karter, A.S. Go Glycemic control and heart failure among adult patients with diabetes Circulation 103 2001 2668 2673
6. D.M. Shindler, J.B. Kostis, S. Yusuf Diabetes mellitus, a predictor of morbidity and mortality in the Studies Of Left Ventricular Dysfunction (SOLVD) trials and registry Am J Cardiol 77 1996 1017 1020
7. The CONSENSUS Trial Study Group Effects of enalapril on mortality in severe congestive heart failure results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS) N Engl J Med 316 1987 1429 1435
8. The SOLVD Investigators Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure N Engl J Med 325 1991 293 302
9. M. Packer, P.A. Poole-Wilson, P.W. Armstrong ATLAS Study Group Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure Circulation 100 1999 2312 2318
10. J.N. Cohn, G. Johnson, S. Ziesche A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure N Engl J Med 325 1991 303 310
11. N. Suskin, R.S. McKelvie, R.J. Burns Glucose and insulin abnormalities relate to functional capacity in patients with congestive heart failure Eur Heart J 21 2000 1368 1375
12. W. Doehner, C.D. Pflaum, M. Rauchhaus Leptin, insulin sensitivity and growth hormone binding protein in chronic heart failure with and without cardiac cachexia Eur J Endocrinol 145 2001 727 735
13. R.N. Bergman, Y.Z. Ider, C.R. Bowden, C. Cobelli Quantitative estimation of insulin sensitivity Am J Physiol 236 1979 E667 E677
14. J.W. Swan, C. Walton, I.F. Godsland Assessment of insulin sensitivity in man a comparison of minimal model and euglycaemic clamp derived measures in health and heart failure Clin Sci 86 1994 317 322
15. S.D. Anker, P.P. Ponikowski, A.L. Clark Cytokines and neurohormones relating to body composition alterations in the wasting syndrome of chronic heart failure Eur Heart J 20 1999 683 693
16. S.D. Anker, J.W. Swan, M. Volterrani The influence of muscle mass, strength, fatigability and blood flow on exercise capacity in cachectic and non-cachectic patients with chronic heart failure Eur Heart J 18 1997 259 269
17. C. Walton, I.F. Godsland, A.J. Proudler, C. Felton, V. Wynn Evaluation of four mathematical models of glucose and insulin dynamics with analysis of effects of age and obesity Am J Physiol 262 1992 E755 E762
18. W.B. Kannel, M. Hjortland, W.P. Castelli Role of diabetes in congestive heart failure the Framingham study Am J Cardiol 34 1974 29 34
19. H. Beck-Nielsen, L.C. Groop Metabolic and genetic characterization of prediabetic states sequence of events leading to non-insulin-dependent diabetes mellitus J Clin Invest 94 1994 1714 1721
20. G. Paolisso, M.R. Tagliamonte, M.R. Rizzo Prognostic importance of insulin-mediated glucose uptake in aged patients with congestive heart failure secondary to mitral and/or aortic valve disease Am J Cardiol 83 1999 1338 1344
21. W. Doehner, S.D. Anker Insulin-mediated glucose uptake in congestive heart failure Am J Cardiol 84 1999 761 762
22. T.B. Horwich, G.C. Fonarow, M.A. Hamilton, W.R. MacLellan, M.A. Woo, J.H. Tillisch The relationship between obesity and mortality in patients with heart failure J Am Coll Cardiol 38 2001 789 795
23. C.H. Davos, W. Doehner, M. Rauchhaus Body mass and survival in patients with chronic heart failure without cachexia the importance of obesity J Card Fail 9 2003 29 35
24. W. Doehner, D.V. Gathercole, M. Cicoira Glucose transport protein GLUT4 levels in skeletal muscle and its relationship to insulin resistance in chronic heart failure (abstr) Circulation 101 Suppl II 2002 II569
25. G.L. Bakris, V. Fonseca, R.E. Katholi GEMINI Investigators Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension a randomized controlled trial JAMA 292 2004 2227 2236
26. M. Bottcher, J. Refsgaard, O. Gotzsche, F. Andreasen, T.T. Nielsen Effect of carvedilol on microcirculatory and glucose metabolic regulation in patients with congestive heart failure secondary to ischemic cardiomyopathy Am J Cardiol 89 2002 1388 1393
27. T.R. Wallhaus, M. Taylor, T.R. DeGrado Myocardial free fatty acid and glucose use after carvedilol treatment in patients with congestive heart failure Circulation 103 2001 2441 2446
28. R. Belardinelli, D. Georgiou, G. Cianci, A. Purcaro Randomized, controlled trial of long-term moderate exercise training in chronic heart failure effects on functional capacity, quality of life, and clinical outcome Circulation 99 1999 1173 1182
29. M.F. Piepoli, C. Davos, D.P. Francis, A.J. Coats ExTraMATCH Collaborative Exercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH) BMJ 328 2004 189 196
30. S. Lund, G.D. Holman, O. Schmitz, O. Pedersen Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin Proc Natl Acad Sci U S A 92 1995 5817 5821