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Volumn , Issue , 2015, Pages 174-180

Febuxostat improves outcome in a rat model of cancer cachexia

Author keywords

Cancer cachexia; Survival; Wasting; Weight loss; Yoshida hepatoma animal model

Indexed keywords

FEBUXOSTAT; PLACEBO; PROTEIN KINASE B;

EID: 84982129695     PISSN: 21905991     EISSN: 21906009     Source Type: Journal    
DOI: 10.1002/jcsm.12017     Document Type: Article
Times cited : (25)

References (32)
  • 3
    • 84888028753 scopus 로고    scopus 로고
    • Cachexia vs obesity: where is the real unmet clinical need?
    • von Haehling S, Anker SD. Cachexia vs obesity: where is the real unmet clinical need? J Cachexia Sarcopenia Muscle 2013; 4: 245–246.
    • (2013) J Cachexia Sarcopenia Muscle , vol.4 , pp. 245-246
    • von Haehling, S.1    Anker, S.D.2
  • 4
    • 11144357623 scopus 로고    scopus 로고
    • Clinical, haemodynamic, anthropometric, metabolic and insulin profile of men with high-stage and high-grade clinical prostate cancer
    • Hammarsten J, Hogstedt B. Clinical, haemodynamic, anthropometric, metabolic and insulin profile of men with high-stage and high-grade clinical prostate cancer. Blood Press 2004; 13: 47–55.
    • (2004) Blood Press , vol.13 , pp. 47-55
    • Hammarsten, J.1    Hogstedt, B.2
  • 5
    • 33745462928 scopus 로고    scopus 로고
    • Uric acid as a prognostic factor for survival time: a prospective cohort study of terminally ill cancer patients
    • Shin HS, Lee HR, Lee DC, Shim JY, Cho KH, Suh SY. Uric acid as a prognostic factor for survival time: a prospective cohort study of terminally ill cancer patients. J Pain Symptom Manage 2006; 31: 493–501.
    • (2006) J Pain Symptom Manage , vol.31 , pp. 493-501
    • Shin, H.S.1    Lee, H.R.2    Lee, D.C.3    Shim, J.Y.4    Cho, K.H.5    Suh, S.Y.6
  • 8
    • 84865533185 scopus 로고    scopus 로고
    • Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia
    • Springer J, Tschirner A, Hartman K, Palus S, Wirth EK, Ruis SB, et al. Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia. Int J Cancer 2012; 131: 2187–2196.
    • (2012) Int J Cancer , vol.131 , pp. 2187-2196
    • Springer, J.1    Tschirner, A.2    Hartman, K.3    Palus, S.4    Wirth, E.K.5    Ruis, S.B.6
  • 9
    • 0027407458 scopus 로고
    • Allopurinol hypersensitivity syndrome: a review
    • Arellano F, Sacristan JA. Allopurinol hypersensitivity syndrome: a review. Ann Pharmacother 1993; 27: 337–343.
    • (1993) Ann Pharmacother , vol.27 , pp. 337-343
    • Arellano, F.1    Sacristan, J.A.2
  • 10
    • 13444257733 scopus 로고    scopus 로고
    • Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase
    • Takano Y, Hase-Aoki K, Horiuchi H, Zhao L, Kasahara Y, Kondo S, et al. Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase. Life Sci 2005; 76: 1835–1847.
    • (2005) Life Sci , vol.76 , pp. 1835-1847
    • Takano, Y.1    Hase-Aoki, K.2    Horiuchi, H.3    Zhao, L.4    Kasahara, Y.5    Kondo, S.6
  • 12
    • 0027331364 scopus 로고
    • Tumor necrosis factor-alpha mediates changes in tissue protein turnover in a rat cancer cachexia model
    • Costelli P, Carbo N, Tessitore L, Bagby GJ, Lopez-Soriano FJ, Argiles JM, et al. Tumor necrosis factor-alpha mediates changes in tissue protein turnover in a rat cancer cachexia model. J Clin Invest 1993; 92: 2783–2789.
    • (1993) J Clin Invest , vol.92 , pp. 2783-2789
    • Costelli, P.1    Carbo, N.2    Tessitore, L.3    Bagby, G.J.4    Lopez-Soriano, F.J.5    Argiles, J.M.6
  • 15
    • 70749095878 scopus 로고    scopus 로고
    • No effects of human ghrelin on cardiac function despite profound effects on body composition in a rat model of heart failure
    • Akashi YJ, Palus S, Datta R, Halem H, Taylor JE, Thoene-Reineke C, et al. No effects of human ghrelin on cardiac function despite profound effects on body composition in a rat model of heart failure. Int J Cardiol 2009; 137: 267–275.
    • (2009) Int J Cardiol , vol.137 , pp. 267-275
    • Akashi, Y.J.1    Palus, S.2    Datta, R.3    Halem, H.4    Taylor, J.E.5    Thoene-Reineke, C.6
  • 17
    • 84874532720 scopus 로고    scopus 로고
    • Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model
    • Lenk K, Palus S, Schur R, Datta R, Dong J, Culler MD, et al. Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model. J Cachexia Sarcopenia Muscle 2013; 4: 63–69.
    • (2013) J Cachexia Sarcopenia Muscle , vol.4 , pp. 63-69
    • Lenk, K.1    Palus, S.2    Schur, R.3    Datta, R.4    Dong, J.5    Culler, M.D.6
  • 19
    • 78049257383 scopus 로고    scopus 로고
    • Akt/protein kinase B in skeletal muscle physiology and pathology
    • Wu M, Falasca M, Blough ER. Akt/protein kinase B in skeletal muscle physiology and pathology. J Cell Physiol 2011; 226: 29–36.
    • (2011) J Cell Physiol , vol.226 , pp. 29-36
    • Wu, M.1    Falasca, M.2    Blough, E.R.3
  • 21
    • 55149124723 scopus 로고    scopus 로고
    • Xanthine oxidase inhibition with febuxostat attenuates systolic overload-induced left ventricular hypertrophy and dysfunction in mice
    • Xu X, Hu X, Lu Z, Zhang P, Zhao L, Wessale JL, et al. Xanthine oxidase inhibition with febuxostat attenuates systolic overload-induced left ventricular hypertrophy and dysfunction in mice. J Card Fail 2008; 14: 746–753.
    • (2008) J Card Fail , vol.14 , pp. 746-753
    • Xu, X.1    Hu, X.2    Lu, Z.3    Zhang, P.4    Zhao, L.5    Wessale, J.L.6
  • 22
    • 79957951218 scopus 로고    scopus 로고
    • Febuxostat inhibition of endothelial-bound XO: implications for targeting vascular ROS production
    • Malik UZ, Hundley NJ, Romero G, Radi R, Freeman BA, Tarpey MM, et al. Febuxostat inhibition of endothelial-bound XO: implications for targeting vascular ROS production. Free Radic Biol Med 2011; 51: 179–184.
    • (2011) Free Radic Biol Med , vol.51 , pp. 179-184
    • Malik, U.Z.1    Hundley, N.J.2    Romero, G.3    Radi, R.4    Freeman, B.A.5    Tarpey, M.M.6
  • 23
    • 84893642740 scopus 로고    scopus 로고
    • Febuxostat contributes to improvement of endothelial dysfunction in an experimental model of streptozocin-induced diabetic rats
    • Hwang SJ, Lee KH, Jang HH, Lee SR, Woo JS, Lee HJ, et al. Febuxostat contributes to improvement of endothelial dysfunction in an experimental model of streptozocin-induced diabetic rats. Int J Cardiol 2014; 171: e110–e112.
    • (2014) Int J Cardiol , vol.171 , pp. e110-e112
    • Hwang, S.J.1    Lee, K.H.2    Jang, H.H.3    Lee, S.R.4    Woo, J.S.5    Lee, H.J.6
  • 24
    • 33751200338 scopus 로고    scopus 로고
    • Acute effects of febuxostat, a nonpurine selective inhibitor of xanthine oxidase, in pacing induced heart failure
    • Hou M, Hu Q, Chen Y, Zhao L, Zhang J, Bache RJ. Acute effects of febuxostat, a nonpurine selective inhibitor of xanthine oxidase, in pacing induced heart failure. J Cardiovasc Pharmacol 2006; 48: 255–263.
    • (2006) J Cardiovasc Pharmacol , vol.48 , pp. 255-263
    • Hou, M.1    Hu, Q.2    Chen, Y.3    Zhao, L.4    Zhang, J.5    Bache, R.J.6
  • 25
    • 84884536123 scopus 로고    scopus 로고
    • Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK
    • Nomura J, Busso N, Ives A, Tsujimoto S, Tamura M, So A, et al. Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK. PLoS One 2013; 8: e75527.
    • (2013) PLoS One , vol.8
    • Nomura, J.1    Busso, N.2    Ives, A.3    Tsujimoto, S.4    Tamura, M.5    So, A.6
  • 26
    • 84873498285 scopus 로고    scopus 로고
    • Long-term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycorticosterone acetate (DOCA)-salt hypertensive rats
    • Szasz T, Davis RP, Garver HS, Burnett RJ, Fink GD, Watts SW. Long-term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycorticosterone acetate (DOCA)-salt hypertensive rats. PLoS One 2013; 8: e56046.
    • (2013) PLoS One , vol.8
    • Szasz, T.1    Davis, R.P.2    Garver, H.S.3    Burnett, R.J.4    Fink, G.D.5    Watts, S.W.6
  • 27
    • 84880778263 scopus 로고    scopus 로고
    • Comparison of febuxostat and allopurinol for hyperuricemia in cardiac surgery patients (NU-FLASH Trial)
    • Sezai A, Soma M, Nakata K, Hata M, Yoshitake I, Wakui S, et al. Comparison of febuxostat and allopurinol for hyperuricemia in cardiac surgery patients (NU-FLASH Trial). Circ J 2013; 77: 2043–2049.
    • (2013) Circ J , vol.77 , pp. 2043-2049
    • Sezai, A.1    Soma, M.2    Nakata, K.3    Hata, M.4    Yoshitake, I.5    Wakui, S.6
  • 28
    • 84892590910 scopus 로고    scopus 로고
    • As compared to allopurinol, urate-lowering therapy with febuxostat has superior effects on oxidative stress and pulse wave velocity in patients with severe chronic tophaceous gout
    • Tausche AK, Christoph M, Forkmann M, Richter U, Kopprasch S, Bielitz C, et al. As compared to allopurinol, urate-lowering therapy with febuxostat has superior effects on oxidative stress and pulse wave velocity in patients with severe chronic tophaceous gout. Rheumatol Int 2014; 34: 101–109.
    • (2014) Rheumatol Int , vol.34 , pp. 101-109
    • Tausche, A.K.1    Christoph, M.2    Forkmann, M.3    Richter, U.4    Kopprasch, S.5    Bielitz, C.6
  • 30
    • 84879112021 scopus 로고    scopus 로고
    • Research on cachexia, sarcopenia and skeletal muscle in cardiology
    • Coats AJ. Research on cachexia, sarcopenia and skeletal muscle in cardiology. J Cachexia Sarcopenia Muscle 2012; 3: 219–223.
    • (2012) J Cachexia Sarcopenia Muscle , vol.3 , pp. 219-223
    • Coats, A.J.1
  • 32
    • 84866549876 scopus 로고    scopus 로고
    • Sarcopenia and cachexia: the adaptations of negative regulators of skeletal muscle mass
    • Sakuma K, Yamaguchi A. Sarcopenia and cachexia: the adaptations of negative regulators of skeletal muscle mass. J Cachexia Sarcopenia Muscle 2012; 3: 77–94.
    • (2012) J Cachexia Sarcopenia Muscle , vol.3 , pp. 77-94
    • Sakuma, K.1    Yamaguchi, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.