Chronic dietary administration of the glycolytic inhibitor 2-deoxy-D-glucose (2-DG) inhibits the growth of implanted Ehrlich's ascites tumor in mice

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Singh, Saurabh ^a,b   Pandey, Sanjay ^a,b   Bhatt, Anant Narayan ^a   Chaudhary, Richa ^b   Bhuria, Vikas ^a   Kalra, Namita ^a   Soni, Ravi ^a   Roy, Bal Gangadhar ^a   Saluja, Daman ^b   Dwarakanath, Bilikere S ^a  

^a INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

^b UNIVERSITY OF DELHI   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CYCLINE; DEOXYGLUCOSE; GELATINASE B; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; ANTINEOPLASTIC ANTIMETABOLITE; GLUCOSE BLOOD LEVEL; MMP9 PROTEIN, MOUSE; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INCIDENCE; CANCER INHIBITION; CANCER PREVENTION; CANCER SURVIVAL; CARCINOGENESIS; CD4 CD8 RATIO; CD4+ CD25+ T LYMPHOCYTE; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; EHRLICH ASCITES TUMOR; FEMALE; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TUMOR INVASION; ANALYSIS; ANIMAL; BLOOD; CALORIC RESTRICTION; CARCINOMA, EHRLICH TUMOR; CELL DIVISION; DRUG EFFECTS; DRUG SCREENING; GLYCOLYSIS; IMMUNOLOGY; NEOVASCULARIZATION, PATHOLOGIC; PHYSIOLOGY; PREMEDICATION; RANDOMIZATION; TUMOR VOLUME; VASCULARIZATION;

ANIMALIA; MUS;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BLOOD GLUCOSE; CALORIC RESTRICTION; CARCINOMA, EHRLICH TUMOR; CD4-CD8 RATIO; CELL DIVISION; DEOXYGLUCOSE; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; GLYCOLYSIS; INSULIN; MATRIX METALLOPROTEINASE 9; MICE; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; PREMEDICATION; RANDOM ALLOCATION; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TUMOR BURDEN;

EID: 84940063528     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0132089     Document Type: Article

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