AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle

Hypertension

Volumn 66, Issue 1, 2015, Pages 108-116

  Schneider, Holger ^a,c,d   Schubert, Kai Michael ^a,c,d   Blodow, Stephanie ^a,c,d   Kreutz, Claus Peter ^a   Erdogmus, Serap ^b   Wiedenmann, Margarethe ^a   Qiu, Jiehua ^a   Fey, Theres ^a,d   Ruth, Peter ^g   Lubomirov, Lubomir T ^f   Pfitzer, Gabriele ^f   Mederos Y Schnitzler, Michael ^b,d   Hardie, D Grahame ^e   Gudermann, Thomas ^b,d   Pohl, Ulrich ^a,c,d  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c Germany 3 Munich Cluster for Systems Neurology   (Germany)

^d DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^e UNIVERSITY OF DUNDEE   (United Kingdom)

^f UNIVERSITY OF COLOGNE   (Germany)

^g UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

muscle, smooth, vascular; phospholamban; vasodilation

Indexed keywords

6,7 DIHYDRO 4 HYDROXY 3 (2' HYDROXY 1,1' BIPHENYL 4 YL) 6 OXOTHIENO[2,3 B]PYRIDINE 5 CARBONITRILE; ARGININE METHYL ESTER; CAFFEINE; CALCIUM; CALCIUM ACTIVATED POTASSIUM CHANNEL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IBERIOTOXIN; INDOMETACIN; MESSENGER RNA; N(G) NITROARGININE METHYL ESTER; NIFEDIPINE; NITRIC OXIDE SYNTHASE; NORADRENALIN; PAXILLINE; PHOSPHOLAMBAN; POTASSIUM CHANNEL; PROSTAGLANDIN SYNTHASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; THAPSIGARGIN; CALCIUM BINDING PROTEIN; INDOLE DERIVATIVE; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT; PEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM DEPLETION; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; EC50; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HAMSTER; HYPERPOLARIZATION; INCUBATION TIME; ISOLATED ARTERY; MEMBRANE STEADY POTENTIAL; MOUSE; NONHUMAN; PHARMACOLOGICAL STIMULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE RELAXATION; TISSUE LEVEL; UPREGULATION; VASCULAR RESISTANCE; VASCULAR SMOOTH MUSCLE; VASCULAR SMOOTH MUSCLE CELL; VASODILATATION; ADRENERGIC SYSTEM; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CALCIUM SIGNALING; CELL CULTURE; DRUG EFFECTS; MEMBRANE POTENTIAL; MESOCRICETUS; METABOLISM; PHYSIOLOGY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CALCIUM SIGNALING; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; CRICETINAE; ENZYME ACTIVATION; INDOLES; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; MEMBRANE POTENTIALS; MESOCRICETUS; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; PEPTIDES; RNA, MESSENGER; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THAPSIGARGIN; VASCULAR RESISTANCE; VASODILATION; VASOMOTOR SYSTEM;

EID: 84940049337     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.115.05514     Document Type: Article

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