Expression of Lactococcus lactis NADH oxidase increases 2,3-butanediol production in Pdc-deficient Saccharomyces cerevisiae

Bioresource Technology

Volumn 191, Issue , 2015, Pages 512-519

  Kim, Jin Woo ^a   Seo, Seung Oh ^b   Zhang, Guo Chang ^b   Jin, Yong Su ^b   Seo, Jin Ho ^a  

^a Seoul National University   (South Korea)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

2,3 Butanediol; Cofactor engineering; Glycerol; NADH oxidase; Saccharomyces cerevisiae

Indexed keywords

GLYCEROL;

2 ,3-BUTANEDIOL; CARBON FLUXES; COFACTOR ENGINEERING; GLYCEROL PRODUCTION; ISOGENIC STRAIN; LACTOCOCCUS LACTIS; NADH OXIDASE; S.CEREVISIAE;

YEAST;

2,3-BUTYLENE GLYCOL; BUTANEDIOL; MULTIENZYME COMPLEX; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ENZYMOLOGY; LACTOCOCCUS LACTIS; METABOLISM; SACCHAROMYCES CEREVISIAE;

BUTYLENE GLYCOLS; LACTOCOCCUS LACTIS; MULTIENZYME COMPLEXES; NADH, NADPH OXIDOREDUCTASES; SACCHAROMYCES CEREVISIAE;

EID: 84940044539     PISSN: 09608524     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biortech.2015.02.077     Document Type: Article

References (35)

1. +-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation EMBO J. 16 9 1997 2179 2187
2. S. Atsumi, Z. Li, and J.C. Liao Acetolactate synthase from Bacillus subtilis serves as a 2-ketoisovalerate decarboxylase for isobutanol biosynthesis in Escherichia coli Appl. Environ. Microbiol. 75 19 2009 6306 6311
3. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1 1976 248 254
4. C. Bro, B. Regenberg, J. Förster, and J. Nielsen In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production Metab. Eng. 8 2 2006 102 111
5. R. Costenoble, H. Valadi, L. Gustafsson, C. Niklasson, and C. Johan Franzén Microaerobic glycerol formation in Saccharomyces cerevisiae Yeast 16 16 2000 1483 1495
6. F.L. De Felipe, M. Kleerebezem, W.M. de Vos, and J. Hugenholtz Cofactor engineering: a novel approach to metabolic engineering in Lactococcus lactis by controlled expression of NADH oxidase J. Bacteriol. 180 15 1998 3804 3808
7. M. Ehsani, M.R. Fernández, J.A. Biosca, A. Julien, and S. Dequin Engineering of 2,3-butanediol dehydrogenase to reduce acetoin formation by glycerol-overproducing, low-alcohol Saccharomyces cerevisiae Appl. Environ. Microbiol. 75 10 2009 3196 3205
8. +) in Saccharomyces cerevisiae, and its comparison with GPD1 Mol. Microbiol. 17 1 1995 95 107
9. M.T. Flikweert, L. van der Zanden, W.M.T.M. Janssen, H. Yde Steensma, J.P. van Dijken, and J.T. Pronk Pyruvate decarboxylase: an indispensable enzyme for growth of Saccharomyces cerevisiae on glucose Yeast 12 3 1996 247 257
10. 2O-forming NADH oxidase and impact on redox metabolism Metab. Eng. 8 4 2006 303 314
11. J. Hou, N.F. Lages, M. Oldiges, and G.N. Vemuri Metabolic impact of redox cofactor perturbations in Saccharomyces cerevisiae Metab. Eng. 11 4 2009 253 261
12. J. Hou, G.N. Vemuri, X. Bao, and L. Olsson Impact of overexpressing NADH kinase on glucose and xylose metabolism in recombinant xylose-utilizing Saccharomyces cerevisiae Appl. Microbiol. Biotechnol. 82 5 2009 909 919
13. N. Ishida, S. Saitoh, T. Onishi, K. Tokuhiro, E. Nagamori, K. Kitamoto, and H. Takahashi The effect of pyruvate decarboxylase gene knockout in Saccharomyces cerevisiae on l-lactic acid production Biosci. Biotechnol. Biochem. 70 5 2006 1148 1153
14. S.-J. Kim, S.-O. Seo, Y.-S. Jin, and J.-H. Seo Production of 2,3-butanediol by engineered Saccharomyces cerevisiae Bioresour. Technol. 146 2013 274 281
15. S.-J. Kim, S.-O. Seo, Y.-C. Park, Y.-S. Jin, and J.-H. Seo Production of 2,3-butanediol from xylose by engineered Saccharomyces cerevisiae J. Biotechnol. 2014 (in press)
16. J. López, B. Thoms, and H. Rehbein Acetoin degradation in Bacillus subtilis by direct oxidative cleavage Eur. J. Biochem. 57 2 1975 425 430
17. M. Moreira dos Santos, V. Raghevendran, P. Kötter, L. Olsson, and J. Nielsen Manipulation of malic enzyme in Saccharomyces cerevisiae for increasing NADPH production capacity aerobically in different cellular compartments Metab. Eng. 6 4 2004 352 363
18. H. Moriya, and M. Johnston Glucose sensing and signaling in Saccharomyces cerevisiae through the Rgt2 glucose sensor and casein kinase I Proc. Natl. Acad. Sci. U.S.A. 101 6 2004 1572 1577
19. D. Mumberg, R. Müller, and M. Funk Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds Gene 156 1 1995 119 122
20. H. Nan, S.-O. Seo, E.J. Oh, J.-H. Seo, J.H. Cate, and Y.-S. Jin 2,3-Butanediol production from cellobiose by engineered Saccharomyces cerevisiae Appl. Microbiol. Biotechnol. 98 2014 5757 5764
21. C.Y. Ng, M.-Y. Jung, J. Lee, and M.-K. Oh Production of 2,3-butanediol in Saccharomyces cerevisiae by in silico aided metabolic engineering Microb. Cell Fact. 11 2012 68
22. J.-I. Nikawa, Y. Tsukagoshi, and S. Yamashita Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae J. Biol. Chem. 266 17 1991 11184 11191
23. T.L. Nissen, M.C. Kielland-Brandt, J. Nielsen, and J. Villadsen Optimization of ethanol production in Saccharomyces cerevisiae by metabolic engineering of the ammonium assimilation Metab. Eng. 2 1 2000 69 77
24. T.L. Nissen, M. Anderlund, J. Nielsen, J. Villadsen, and M.C. Kielland-Brandt Expression of a cytoplasmic transhydrogenase in Saccharomyces cerevisiae results in formation of 2-oxoglutarate due to depletion of the NADPH pool Yeast 18 1 2001 19 32
25. B. Oud, C.-L. Flores, C. Gancedo, X. Zhang, J. Trueheart, J.-M. Daran, J.T. Pronk, and A. van Maris An internal deletion in MTH1 enables growth on glucose of pyruvate-decarboxylase negative, non-fermentative Saccharomyces cerevisiae Microb. Cell Fact. 11 2012 131
26. J. Paciorek-Sadowska, and B. Czupryński New compounds for production of polyurethane foams J. Appl. Polym. Sci. 102 6 2006 5918 5926
27. K. Petrov, and P. Petrova High production of 2,3-butanediol from glycerol by Klebsiella pneumoniae G31 Appl. Microbiol. Biotechnol. 84 4 2009 659 665
28. N. Qureshi, and M. Cheryan Production of 2,3-butanediol by Klebsiella oxytoca Appl. Microbiol. Biotechnol. 30 5 1989 440 443
29. P. Romano, and G. Suzzi Origin and production of acetoin during wine yeast fermentation Appl. Environ. Microbiol. 62 2 1996 309
30. M.-J. Syu Biological production of 2,3-butanediol Appl. Microbiol. Biotechnol. 55 1 2001 10 18
31. A.V. Tran, and R.P. Chambers The dehydration of fermentative 2,3-butanediol into methyl ethyl ketone Biotechnol. Bioeng. 29 3 1987 343 351
32. 2-independent, glucose-tolerant, and pyruvate-hyperproducing yeast Appl. Environ. Microbiol. 70 1 2004 159 166
33. G. Vemuri, M. Eiteman, J. McEwen, L. Olsson, and J. Nielsen Increasing NADH oxidation reduces overflow metabolism in Saccharomyces cerevisiae Proc. Natl. Acad. Sci. U.S.A. 104 7 2007 2402 2407
34. R. Verho, J. Londesborough, M. Penttilä, and P. Richard Engineering redox cofactor regeneration for improved pentose fermentation in Saccharomyces cerevisiae Appl. Environ. Microbiol. 69 10 2003 5892 5897
35. L. Zhang, Y. Yang, J.A. Sun, Y. Shen, D. Wei, J. Zhu, and J. Chu Microbial production of 2,3-butanediol by a mutagenized strain of Serratia marcescens H30 Bioresour. Technol. 101 6 2010 1961 1967