Surface modification of paclitaxel-loaded tri-block copolymer PLGA-b-PEG-b-PLGA nanoparticles with protamine for liver cancer therapy

Journal of Nanoparticle Research

Volumn 17, Issue 8, 2015, Pages

  Gao, Nansha ^a   Chen, Zhihong ^b   Xiao, Xiaojun ^d   Ruan, Changshun ^a   Mei, Lin ^c   Liu, Zhigang ^d   Zeng, Xiaowei ^c  

^a SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY   (China)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

^c TSINGHUA UNIVERSITY   (China)

^d Shenzhen University School of Medicine   (China)

Author keywords

Cancer nanotechnology; Nanoparticle; PLGA b PEG b PLGA; Protamine; Surface modification

Indexed keywords

BLOCK COPOLYMERS; CELL CULTURE; CHEMOTHERAPY; DISEASES; DRUG PRODUCTS; ENCAPSULATION; GEL PERMEATION CHROMATOGRAPHY; NANOPARTICLES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYETHYLENE OXIDES; RING OPENING POLYMERIZATION; SURFACE TREATMENT;

CANCER NANOTECHNOLOGY; CELLULAR UPTAKE EFFICIENCY; CONFOCAL LASER SCANNING MICROSCOPY; DRUG ENCAPSULATION EFFICIENCY; HEPATOCELLULAR CARCINOMA CELL; PLGA-B-PEG-B-PLGA; POLY LACTIDE-CO-GLYCOLIDE; PROTAMINE;

POLYETHYLENE GLYCOLS;

COPOLYMER; COUMARIN; NANOCARRIER; NANOPARTICLE; PACLITAXEL; POLY(LACTIDE CO GLYCOLIDE) BLOCK POLY(ETHYLENE GLYCOL) BLOCK POLY(LACTIDE CO GLYCOLIDE); PROTAMINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG RELEASE; DRUG SYNTHESIS; ENCAPSULATION; GEL PERMEATION CHROMATOGRAPHY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; INTERNALIZATION; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RING OPENING; SURFACE MODIFICATION; SURFACE PROPERTY; ZETA POTENTIAL;

EID: 84940036524     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-015-3121-3     Document Type: Article

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