Self-assembled hyaluronate/protamine polyelectrolyte nanoplexes: Synthesis, stability, biocompatibility and potential use as peptide carriers

Journal of Biomedical Nanotechnology

Volumn 10, Issue 12, 2014, Pages 3658-3673

  Umerska, Anita ^a   Paluch, Krzysztof J ^a   Martinez, Maria Jose Santos ^a,b   Corrigan, Owen I ^a   Medina, Carlos ^a   Tajber, Lidia ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Caco 2 cells; Calcitonin; Hyaluronic acid; Nanoparticles; Polyelectrolyte complex; Protamine

Indexed keywords

BIOCOMPATIBILITY; LOADING; NANOPARTICLES; ORGANIC ACIDS; PEPTIDES; POLYELECTROLYTES; TISSUE;

CACO 2-CELLS; CALCITONIN; ENZYMATIC DEGRADATION; INTESTINAL EPITHELIAL CELLS; NEGATIVE SURFACE CHARGES; POLYDISPERSITY INDICES; POLYELECTROLYTE COMPLEXES; PROTAMINE;

HYALURONIC ACID;

HYALURONIC ACID; NANOPARTICLE; PEPTIDE; POLYELECTROLYTE; PROTAMINE SULFATE; SALCATONIN; BIOMATERIAL; CALCITONIN; ELECTROLYTE; NANOCONJUGATE; PROTAMINE;

ARTICLE; BIOCOMPATIBILITY; CACO 2 CELL LINE; CHEMICAL COMPOSITION; CHEMICAL INTERACTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; ENZYME DEGRADATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; ISOELECTRIC POINT; MOLECULAR WEIGHT; PARTICLE SIZE; PEPTIDE SYNTHESIS; PH; PH MEASUREMENT; CELL SURVIVAL; CHEMISTRY; DIFFUSION; DRUG EFFECTS; MATERIALS TESTING; SYNTHESIS; ULTRASTRUCTURE;

BIOCOMPATIBLE MATERIALS; CACO-2 CELLS; CALCITONIN; CELL SURVIVAL; DIFFUSION; DRUG STABILITY; ELECTROLYTES; HUMANS; HYALURONIC ACID; MATERIALS TESTING; NANOCONJUGATES; PARTICLE SIZE; PROTAMINES;

EID: 84908234924     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2014.1878     Document Type: Article

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