Preparation of nanoparticles composed of poly(γ-glutamic acid)-poly(lactide) block copolymers and evaluation of their uptake by HepG2 cells

Journal of Controlled Release

Volumn 105, Issue 3, 2005, Pages 213-225

  Liang, Hsiang Fa ^a   Yang, Ting Fan ^a   Huang, Chin Tsung ^a   Chen, Mei Chin ^a   Sung, Hsing Wen ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

Active targeting; Amphiphilic block copolymer; Drug delivery system; HepG2 cell; Nanoparticle

Indexed keywords

BLOCK COPOLYMERS; CELLS; HYDROLYSIS; ORGANIC ACIDS; SELF ASSEMBLY; TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

MOIETIES; NEGATIVE CHARGE; POLY(LACTIDE) (PLA); ZETA POTENTIAL;

NANOSTRUCTURED MATERIALS;

GALACTOSAMINE; GLUTAMIC ACID DERIVATIVE; NANOPARTICLE; POLY(GAMMA GLUTAMIC ACID); POLYLACTIDE; POLYMER; RHODAMINE 123; UNCLASSIFIED DRUG;

ARTICLE; ATOMIC FORCE MICROSCOPY; BACILLUS LICHENIFORMIS; BIODEGRADABILITY; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; ELECTRIC POTENTIAL; ELECTRICITY; FERMENTATION; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; HYDROLYSIS; LINEAR SYSTEM; LIVER CANCER; MOLECULAR WEIGHT; MORPHOLOGY; NONHUMAN; PARTICLE SIZE; PRECIPITATION; PRIORITY JOURNAL; PROTEIN INTERACTION; STATISTICAL SIGNIFICANCE; STORAGE; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

CELL LINE, TUMOR; CHEMISTRY, PHYSICAL; FLUORESCENT DYES; GALACTOSAMINE; HUMANS; HYDROLYSIS; LACTIC ACID; LIGHT; LIVER NEOPLASMS; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSPHERES; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; RHODAMINE 123; SCATTERING, RADIATION; SPECTROMETRY, FLUORESCENCE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES;

EID: 21744446564     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.03.021     Document Type: Article

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