Histone deacetylase 3 (HDAC3)-dependent reversible lysine acetylation of cardiac myosin heavy chain isoforms modulates their enzymatic and motor activity

Journal of Biological Chemistry

Volumn 290, Issue 25, 2015, Pages 15559-15569

  Samant, Sadhana A ^a   Pillai, Vinodkumar B ^a   Sundaresan, Nagalingam R ^a   Shroff, Sanjeev G ^b   Gupta, Mahesh P ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; AMINO ACIDS; CHAINS; HEART;

BIOMECHANICAL STUDIES; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASES; MICROSCOPIC ANALYSIS; MYOSIN HEAVY CHAIN; POST-TRANSLATIONAL MODIFICATIONS; PROTEIN-ASSOCIATED FACTORS; SUBCELLULAR COMPARTMENTS;

PROTEINS;

ADENOSINE TRIPHOSPHATASE; HISTONE DEACETYLASE 3; LYSINE; MYOSIN HEAVY CHAIN ALPHA; MYOSIN HEAVY CHAIN BETA; HISTONE DEACETYLASE; ISOENZYME; MYOSIN HEAVY CHAIN;

ACETYLATION; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MOTILITY; CONTROLLED STUDY; DEACETYLATION; ELECTRON MICROSCOPY; ENZYME ACTIVITY; HEART CONTRACTION; HEART STRESS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN TARGETING; SARCOMERE; UPREGULATION; ANIMAL; CARDIAC MUSCLE; CARDIOMEGALY; ENZYMOLOGY; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ACETYLATION; ANIMALS; CARDIOMEGALY; HISTONE DEACETYLASES; ISOENZYMES; MALE; MICE; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOSIN HEAVY CHAINS; SARCOMERES;

EID: 84940026581     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.653048     Document Type: Article

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