A new approach using micro HPLC-MS/MS for multi-mycotoxin analysis in maize samples

Mycotoxin Research

Volumn 31, Issue 2, 2015, Pages 109-115

  Hickert, Sebastian ^a,b,c   Gerding, Johannes ^a,b,c   Ncube, Edson ^a,b,c   Hübner, Florian ^a,b,c   Flett, Bradley ^a,b,c   Cramer, Benedikt ^a,b,c   Humpf, Hans Ulrich ^a,b,c  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b ARC GRAIN CROPS INSTITUTE   (South Africa)

^c NORTH WEST UNIVERSITY   (South Africa)

Author keywords

Aflatoxin; Capillary chromatography; Mass spectrometry; Micro LC; Multi method

Indexed keywords

MYCOTOXIN;

CHEMISTRY; COST BENEFIT ANALYSIS; FOOD CONTAMINATION; FOOD SAFETY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MAIZE; PROCEDURES; TANDEM MASS SPECTROMETRY; TIME;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COST-BENEFIT ANALYSIS; FOOD CONTAMINATION; FOOD SAFETY; MYCOTOXINS; TANDEM MASS SPECTROMETRY; TIME FACTORS; ZEA MAYS;

EID: 84939974580     PISSN: 01787888     EISSN: 18671632     Source Type: Journal    
DOI: 10.1007/s12550-015-0221-y     Document Type: Article

References (35)

1. 3-HT-2 toxin. Mycotox Res 25:41–52
2. Bretz M, Beyer M, Cramer B, Humpf H-U (2006) Stable isotope dilution analysis of the Fusarium mycotoxins deoxynivalenol and 3-acetyldeoxynivalenol. Mol Nutr Food Res 50:251–260
3. Codex Alimentarius Committee (CAC) (1995) Codex general standard for contaminants and toxins in food and feed. (http://www.fao.org/fileadmin/user_upload/agns/pdf/CXS_193e.pdf)
4. Codex Alimentarius Committee (CAC) (2003) Code of practice for the prevention and reduction of mycotoxin contamination in cereals, including annexes on ochratoxin a, zearalenone, fumonisins and trichothecenes, 2003 http://www.codexalimentarius.org/input/download/standards/406/CXP_051e.pdf
5. Cramer B, Bretz M, Humpf H-U (2007) Stable isotope dilution analysis of the Fusarium mycotoxin zearalenone. J Agr Food Chem 21:8353–8358
6. Cramer B, Königs M, Humpf H-U (2008) Identification and in vitro cytotoxicity of ochratoxin a degradation products formed during coffee roasting. J Agr Food Chem 56:5673–5681
7. Department of Health, Government of South Africa (DoH) (2004) Notice No. 26849. Regulations governing tolerance for fungus-produced toxins in foodstuffs. Regulation for Act No. 54 of 1972
8. European Commission Recommendation (EC) (2013) EC 2013/165/EU on the presence of T-2 and HT-2 toxin in cereals and cereal products. O J L91, 12-15
9. European Commission Regulation (EC) (2006) EC 401/2003 Laying down the methods of sampling and analysis for the official control of the levels of mycotoxins in foodstuffs. O J L70, 12-34
10. European Commission Regulation (EC) (2006) EC 1881/2006 Setting maximum levels for certain contaminants in foodstuffs. O J L364, 15-17
11. European Committee for Standardization (CEN) (2010) Food analysis―performance criteria for single laboratory validated methods of analysis for the determination of mycotoxins (CEN/TR 16059:2010). Austrian Standards Institute, Vienna
12. European Food Safety Authority (EFSA) (2011) Scientific opinion on the risks for animal and public health related to the presence of Alternaria toxins in feed and food. EFSA J 9(10):2407, 1-97
13. European Food Safety Authority (EFSA) (2013) Scientific opinion on the risk for public and animal health related to the presence of sterigmatocystin in food and feed. EFSA J 11(6):3254, 1-81
14. European Food Safety Authority (EFSA) (2014) Request for an EFSA opinion on the risks to human and animal health related to the presence of beauvericin and enniatins in food and feed. (http://registerofquestions.efsa.europa.eu/raw-war/?wicket:interface=:4)
15. Frenich AG, Vidal JLM, del Romero-González R, Mar Aguilera-Luiz M (2009) Simple and high-throughput method for multimycotoxin analysis in cereals and related foods by ultra-high performance liquid chromatography/tandem mass spectrometry. Food Chem 117:705–712
16. Goryacheva IY, De Saeger S, Eremin SA, Peteghem C (2007) Immunochemical methods for rapid mycotoxin detection: evolution from single to multi analyte screening: a review. Food Addit Contam 24:1169–1183
17. Goswami RS, Kistler HC (2004) Heading for disaster: Fusarium graminearum on cereal crops. Mol Plant Pathol 5(6):515–525
18. Herzallah SM (2009) Determination of aflatoxins in eggs, milk, meat and meat products using HPLC fluorescent and UV detectors. Food Chem 114:1141–1146
19. Hübner F, Harrer H, Fraske A, Kneifel S, Humpf H-U (2012) Large scale purification of B-type fumonisins using centrifugal partition chromatography (CPC). Mycotox Res 28:37–43
20. Ishii D, Asai K, Hibi K, Jonokuchi T, Nagaya M (1977) A study of micro-high-performance liquid chromatography I development of technique for miniaturization of high-performance liquid chromatography. J Chromatogr 144:157–168
21. Kleigrewe K, Niehaus E-M, Wiemann P, Tudzynski B, Humpf H-U (2012) New approach via gene knockout and single-step chemical reaction for the synthesis of isotopically labeled fusarin C as an internal standard for the analysis of this Fusarium mycotoxin in food and feed samples. J Agr Food Chem 60(34):8350–8355
22. Legido-Quigley C, Smith NW, Mallet D (2002) Quantification of the sensitivity increase of a micro-high-performance liquid chromatography-electrospray ionization mass spectrometry system with decreasing column diameter. J Chromatogr A 976:11–18
23. 2 in corn and corn products by high-performance liquid chromatography-electrospray-ionization tandem mass spectrometry (HPLC-ESI-MS-MS). Chromatographia 43:124–128
24. Monbaliu S, Poucke CV, Detavernier C, Dumoulin F, Van de Velde M, Schoeters E, Van Dyck S, Averkieva O, Van Peteghem C, De Saeger S (2010) Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. Food Chem 58:66–71
25. Oueslati S, Romero-González R, Lasram S, Frenich AG, Vidal JLM (2012) Multi-mycotoxin determination in cereals and derived products marketed in Tunisia using ultra-high performance liquid chromatography coupled to triple quadrupole mass spectrometry. Food Chem Toxicol 50:2376–2381
26. Pearson SM, Candish AAG, Aidoo KE, Smith JE (1999) Determination of aflatoxin levels in pistachio and cashew nuts using immunoaffinity column clean-Up with HPLC and fluorescence detection. Biotechnol Tech 13:97–99
27. Rasmussen RR, Storm IMLD, Rasmussen PH, Smedsgaard J, Nielsen KF (2010) Multi-mycotoxin analysis of maize silage by LC-MS/MS. Anal Bioanal Chem 397:765–776
28. Ren Y, Zhang Y, Shao S, Cai Z, Feng L, Wang Z (2007) Simultaneous determination of multi-component mycotoxins residues in foods and feeds by ultra performance liquid chromatography tandem mass spectrometry. J Chromatogr A 1143:48–64
29. Soriano JM, Gragacci S (2004) Occurrence of fumonisins in foods. Food Res Int 37:985–1000
30. Spanjer MC, Rensen PM, Scholten JM (2008) LC-MS/MS multi-method for mycotoxins after single extraction, with validation data for peanut, pistachio, wheat, maize, cornflakes, raisins and figs. Food Addit Contam 25(4):472–489
31. Sulyok M, Berthiller F, Krska R, Schuhmacher R (2006) Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize. Rapid Commun Mass Sp 20:2649–2659
32. Sulyok M, Krska R, Schuhmacher R (2007) A liquid chromatography/tandem mass spectrometric multi-mycotoxin method for the quantification of 87 analytes and its application to semi-quantitative screening of moldy food samples. Anal Bioanal Chem 389:1505–1523
33. Sulyok M, Krska R, Schuhmacher R (2010) Application of an LC-MS/MS based multi-mycotoxin method for the semi-quantitative determination of mycotoxins occurring in different types of food infected by moulds. Food Chem 119:408–416
34. Takeuchi T, Ishii D (1980) Ultra-micro high-performance liquid chromatography. J Chromatogr 190:150–155
35. Tanaka T, Yoneda A, Inoue S, Sugiura Y, Ueno Y (2000) Simultaneous determination of trichothecene mycotoxins and zearalenone in cereals by gas chromatography-mass spectrometry. J Chromatogr A 882:23–28