Mastoparan induces apoptosis in B16F10-Nex2 melanoma cells via the intrinsic mitochondrial pathway and displays antitumor activity in vivo

Peptides

Volumn 68, Issue , 2015, Pages 113-119

  De Azevedo, Ricardo A ^a   Figueiredo, Carlos R ^b   Ferreira, Adilson K ^c   Matsuo, Alisson L ^b   Massaoka, Mariana H ^b   Girola, Natalia ^b   Auada, Aline V V ^a   Farias, Camyla F ^b   Pasqualoto, Kerly F M ^a   Rodrigues, Cecília P ^c   Barbuto, José A ^c   Levy, Debora ^c   Bydlowski, Sérgio P ^c   De Sá Junior, Paulo L ^a   Travassos, Luiz R ^b   Lebrun, Ivo ^a  

^a INSTITUTO BUTANTAN   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antitumor effects in vivo; Apoptosis; Intrinsic pathway; Mastoparan; Melanoma

Indexed keywords

ANTINEOPLASTIC AGENT; MASTOPARAN; PEPTIDE; WASP VENOM;

ANIMAL; APOPTOSIS; C57BL MOUSE; CANCER TRANSPLANTATION; CELL SHAPE; DRUG EFFECTS; DRUG SCREENING; MALE; MELANOMA, EXPERIMENTAL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OXIDATIVE STRESS; PATHOLOGY; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL SHAPE; DRUG SCREENING ASSAYS, ANTITUMOR; MALE; MELANOMA, EXPERIMENTAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE, INBRED C57BL; MITOCHONDRIA; NEOPLASM TRANSPLANTATION; OXIDATIVE STRESS; PEPTIDES; TUMOR BURDEN; WASP VENOMS;

EID: 84939945047     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2014.09.024     Document Type: Article

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