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Volumn 459, Issue 3, 2015, Pages 430-436

A PKM2 signature in the failing heart

Author keywords

Fetal gene program; Glycolysis; Heart failure; Hif1 ; PKM2; Sunitinib

Indexed keywords

ANGIOGENESIS INHIBITOR; CARRIER PROTEIN; GLUCOSE; HIF1A PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDOLE DERIVATIVE; MEMBRANE PROTEIN; PYRROLE DERIVATIVE; PYRUVATE KINASE; SUNITINIB; THYROID HORMONE; THYROID HORMONE-BINDING PROTEINS;

EID: 84939940590     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.02.122     Document Type: Article
Times cited : (78)

References (32)
  • 2
    • 77649087980 scopus 로고    scopus 로고
    • Return to the fetal gene program: A suggested metabolic link to gene expression in the heart
    • H. Taegtmeyer, S. Sen, and D. Vela Return to the fetal gene program: a suggested metabolic link to gene expression in the heart Ann. N. Y. Acad. Sci. 1188 2010 191 198
    • (2010) Ann. N. Y. Acad. Sci. , vol.1188 , pp. 191-198
    • Taegtmeyer, H.1    Sen, S.2    Vela, D.3
  • 4
    • 80053339992 scopus 로고    scopus 로고
    • Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice
    • N.M. Agostino, V.M. Chinchilli, C.J. Lynch, A. Koszyk-Szewczyk, R. Gingrich, J. Sivik, and J.J. Drabick Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice J. Oncol. Pharm. Pract. 17 2011 197 202
    • (2011) J. Oncol. Pharm. Pract. , vol.17 , pp. 197-202
    • Agostino, N.M.1    Chinchilli, V.M.2    Lynch, C.J.3    Koszyk-Szewczyk, A.4    Gingrich, R.5    Sivik, J.6    Drabick, J.J.7
  • 5
    • 55249116969 scopus 로고    scopus 로고
    • Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib
    • B. Billemont, J. Medioni, L. Taillade, D. Helley, J.B. Meric, O. Rixe, and S. Oudard Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib Br. J. Cancer 99 2008 1380 1382
    • (2008) Br. J. Cancer , vol.99 , pp. 1380-1382
    • Billemont, B.1    Medioni, J.2    Taillade, L.3    Helley, D.4    Meric, J.B.5    Rixe, O.6    Oudard, S.7
  • 6
    • 41549093594 scopus 로고    scopus 로고
    • Remission of diabetes while on sunitinib treatment for renal cell carcinoma
    • A. Templeton, M. Brandle, T. Cerny, and S. Gillessen Remission of diabetes while on sunitinib treatment for renal cell carcinoma Ann. Oncol. 19 2008 824 825
    • (2008) Ann. Oncol. , vol.19 , pp. 824-825
    • Templeton, A.1    Brandle, M.2    Cerny, T.3    Gillessen, S.4
  • 8
    • 57349174523 scopus 로고    scopus 로고
    • Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib
    • B.B. Hasinoff, D. Patel, and K.A. O'Hara Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib Mol. Pharmacol. 74 2008 1722 1728
    • (2008) Mol. Pharmacol. , vol.74 , pp. 1722-1728
    • Hasinoff, B.B.1    Patel, D.2    O'Hara, K.A.3
  • 9
    • 55549144710 scopus 로고    scopus 로고
    • Therapy insight: Management of cardiovascular disease in patients with cancer and cardiac complications of cancer therapy
    • A.Y. Khakoo, and E.T. Yeh Therapy insight: management of cardiovascular disease in patients with cancer and cardiac complications of cancer therapy Nat. Clin. Pract. Oncol. 5 2008 655 667
    • (2008) Nat. Clin. Pract. Oncol. , vol.5 , pp. 655-667
    • Khakoo, A.Y.1    Yeh, E.T.2
  • 10
    • 79960262279 scopus 로고    scopus 로고
    • Molecular mechanisms of hypertension and heart failure due to antiangiogenic cancer therapies
    • M.L. Rees, and A.Y. Khakoo Molecular mechanisms of hypertension and heart failure due to antiangiogenic cancer therapies Heart Fail. Clin. 7 2011 299 311
    • (2011) Heart Fail. Clin. , vol.7 , pp. 299-311
    • Rees, M.L.1    Khakoo, A.Y.2
  • 11
    • 50649099256 scopus 로고    scopus 로고
    • Clinical effect and future considerations for molecularly-targeted therapy in renal cell carcinoma
    • B.I. Rini, and K. Flaherty Clinical effect and future considerations for molecularly-targeted therapy in renal cell carcinoma Urol. Oncol. 26 2008 543 549
    • (2008) Urol. Oncol. , vol.26 , pp. 543-549
    • Rini, B.I.1    Flaherty, K.2
  • 14
  • 15
    • 76649102764 scopus 로고    scopus 로고
    • The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
    • C.V. Clower, D. Chatterjee, Z. Wang, L.C. Cantley, M.G. Vander Heiden, and A.R. Krainer The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism Proc. Natl. Acad. Sci. U S A 107 2010 1894 1899
    • (2010) Proc. Natl. Acad. Sci. U S A , vol.107 , pp. 1894-1899
    • Clower, C.V.1    Chatterjee, D.2    Wang, Z.3    Cantley, L.C.4    Vander Heiden, M.G.5    Krainer, A.R.6
  • 17
    • 35848955451 scopus 로고    scopus 로고
    • Return to the fetal gene program protects the stressed heart: A strong hypothesis
    • M. Rajabi, C. Kassiotis, P. Razeghi, and H. Taegtmeyer Return to the fetal gene program protects the stressed heart: a strong hypothesis Heart Fail. Rev. 12 2007 331 343
    • (2007) Heart Fail. Rev. , vol.12 , pp. 331-343
    • Rajabi, M.1    Kassiotis, C.2    Razeghi, P.3    Taegtmeyer, H.4
  • 18
    • 0001221508 scopus 로고
    • On respiratory impairment in cancer cells
    • O. Warburg On respiratory impairment in cancer cells Science 124 1956 269 270
    • (1956) Science , vol.124 , pp. 269-270
    • Warburg, O.1
  • 20
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • M.G. Vander Heiden, L.C. Cantley, and C.B. Thompson Understanding the Warburg effect: the metabolic requirements of cell proliferation Science 324 2009 1029 1033
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 21
    • 84882334678 scopus 로고    scopus 로고
    • Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy
    • Z. Gao, and T.A. Cooper Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy Proc. Natl. Acad. Sci. U S A 110 2013 13570 13575
    • (2013) Proc. Natl. Acad. Sci. U S A , vol.110 , pp. 13570-13575
    • Gao, Z.1    Cooper, T.A.2
  • 24
    • 0141564928 scopus 로고    scopus 로고
    • Mechanical unloading of the failing human heart fails to activate the protein kinase B/Akt/glycogen synthase kinase-3beta survival pathway
    • P. Razeghi, B.A. Bruckner, S. Sharma, K.A. Youker, O.H. Frazier, and H. Taegtmeyer Mechanical unloading of the failing human heart fails to activate the protein kinase B/Akt/glycogen synthase kinase-3beta survival pathway Cardiology 100 2003 17 22
    • (2003) Cardiology , vol.100 , pp. 17-22
    • Razeghi, P.1    Bruckner, B.A.2    Sharma, S.3    Youker, K.A.4    Frazier, O.H.5    Taegtmeyer, H.6
  • 25
    • 84874889081 scopus 로고    scopus 로고
    • PKM2, a central point of regulation in cancer metabolism
    • N. Wong, J. De Melo, and D. Tang PKM2, a central point of regulation in cancer metabolism Int. J. Cell. Biol. 2013 2013 242513
    • (2013) Int. J. Cell. Biol. , vol.2013 , pp. 242513
    • Wong, N.1    De Melo, J.2    Tang, D.3
  • 28
    • 75149150660 scopus 로고    scopus 로고
    • HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
    • C.J. David, M. Chen, M. Assanah, P. Canoll, and J.L. Manley HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer Nature 463 2010 364 368
    • (2010) Nature , vol.463 , pp. 364-368
    • David, C.J.1    Chen, M.2    Assanah, M.3    Canoll, P.4    Manley, J.L.5
  • 30
    • 35649014840 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1
    • J.W. Kim, P. Gao, Y.C. Liu, G.L. Semenza, and C.V. Dang Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1 Mol. Cell. Biol. 27 2007 7381 7393
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 7381-7393
    • Kim, J.W.1    Gao, P.2    Liu, Y.C.3    Semenza, G.L.4    Dang, C.V.5
  • 31
  • 32
    • 84862776933 scopus 로고    scopus 로고
    • Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase
    • X. Gao, H. Wang, J.J. Yang, X. Liu, and Z.R. Liu Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase Mol. Cell. 45 2012 598 609
    • (2012) Mol. Cell. , vol.45 , pp. 598-609
    • Gao, X.1    Wang, H.2    Yang, J.J.3    Liu, X.4    Liu, Z.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.