Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 33, 2013, Pages 13570-13575

  Gao, Zhihua ^a,b   Cooper, Thomas A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Alternative splicing; Muscular dystrophy; Redirected splicing; Striated muscle development

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; LACTIC ACID; PYRUVATE KINASE; PYRUVATE KINASE M2; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; CALORIMETRY; CELL DIFFERENTIATION; CONTROLLED STUDY; ENERGY EXPENDITURE; ENERGY METABOLISM; ENERGY YIELD; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLUCOSE INTAKE; GLUCOSE METABOLISM; HEART DEVELOPMENT; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; LUNG GAS EXCHANGE; MOUSE; MUSCLE ATROPHY; MUSCLE CELL; MUSCLE WEAKNESS; MYOBLAST; MYOTONIC DYSTROPHY; MYOTUBE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SKELETAL MUSCLE; SOLEUS MUSCLE; WESTERN BLOTTING;

ALTERNATIVE SPLICING; MUSCULAR DYSTROPHY; REDIRECTED SPLICING; STRIATED MUSCLE DEVELOPMENT;

ALTERNATIVE SPLICING; ANIMALS; BLOTTING, WESTERN; CALORIMETRY, INDIRECT; CELL LINE; ENERGY METABOLISM; GLUCOSE; HUMANS; IMMUNOHISTOCHEMISTRY; LACTIC ACID; MICE; MUSCLE FIBERS, SLOW-TWITCH; MYOTONIC DYSTROPHY; OLIGORIBONUCLEOTIDES, ANTISENSE; OXYGEN CONSUMPTION; PYRUVATE KINASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84882334678     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1308806110     Document Type: Article

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