Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria

Nature Chemical Biology

Volumn 11, Issue 4, 2015, Pages 292-298

  Landeta, Cristina ^a   Blazyk, Jessica L ^a   Hatahet, Feras ^a   Meehan, Brian M ^a   Eser, Markus ^a   Myrick, Alissa ^b   Bronstain, Ludmila ^a   Minami, Shoko ^b   Arnold, Holly ^a,c   Ke, Na ^a,d   Rubin, Eric J ^b   Furie, Barbara C ^a   Furie, Bruce ^a   Beckwith, Jon ^a   Dutton, Rachel ^a,e   Boyd, Dana ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c NEW ENGLAND BIOLABS   (United States)

^d Oregon State University   (United States)

^e HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGAR; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; DISULFIDE; DSBA PROTEIN, E COLI; DSBB PROTEIN, BACTERIA; ESCHERICHIA COLI PROTEIN; MEMBRANE PROTEIN; PROTEIN DISULFIDE ISOMERASE;

ANTAGONISTS AND INHIBITORS; CHEMISTRY; COMBINATORIAL CHEMISTRY; DOSE RESPONSE; DRUG DESIGN; ELECTRON TRANSPORT; ENZYME ACTIVE SITE; ESCHERICHIA COLI; MASS SPECTROMETRY; MEDICINAL CHEMISTRY; METABOLISM; MICROBIAL SENSITIVITY TEST; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PROCEDURES; PROTEIN CONFORMATION; PSEUDOMONAS AERUGINOSA;

AGAR; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CHEMISTRY, PHARMACEUTICAL; COMBINATORIAL CHEMISTRY TECHNIQUES; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ELECTRON TRANSPORT; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MASS SPECTROMETRY; MEMBRANE PROTEINS; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN CONFORMATION; PROTEIN DISULFIDE-ISOMERASES; PSEUDOMONAS AERUGINOSA;

EID: 84939935179     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1752     Document Type: Article

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