The lipophilic vitamin C derivative, 6-o-palmitoylascorbate, protects human lymphocytes, preferentially over ascorbate, against X-ray-induced DNA damage, lipid peroxidation, and protein carbonylation

Molecular and Cellular Biochemistry

Volumn 394, Issue 1-2, 2014, Pages 247-259

  Xiao, Li ^a   Tsutsui, Takeki ^a   Miwa, Nobuhiko ^b  

^a NIPPON DENTAL UNIVERSITY   (Japan)

^b BUTSURYO COLLEGE OF OSAKA   (Japan)

Author keywords

6 o palmitoylascorbate; DNA damage; Lipid peroxidation; Protein carbonylation; Radioprotection

Indexed keywords

6-O-PALMITOYLASCORBIC ACID; ANTIOXIDANT; ASCORBIC ACID; GLUTATHIONE; H2AFX PROTEIN, HUMAN; HISTONE; PALMITIC ACID DERIVATIVE; REACTIVE OXYGEN METABOLITE;

ANALOGS AND DERIVATIVES; APOPTOSIS; CELL CULTURE; CELL PROTECTION; CELL SURVIVAL; COMPARATIVE STUDY; DOSE RESPONSE; DOUBLE STRANDED DNA BREAK; DRUG EFFECTS; DRUG STABILITY; HUMAN; LIPID PEROXIDATION; LYMPHOCYTE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PROTEIN CARBONYLATION; RADIATION RESPONSE; TIME; X RAY;

ANTIOXIDANTS; APOPTOSIS; ASCORBIC ACID; CELL SURVIVAL; CELLS, CULTURED; CYTOPROTECTION; DNA BREAKS, DOUBLE-STRANDED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG STABILITY; GLUTATHIONE; HISTONES; HUMANS; LIPID PEROXIDATION; LYMPHOCYTES; OXIDATIVE STRESS; PALMITATES; PROTEIN CARBONYLATION; REACTIVE OXYGEN SPECIES; TIME FACTORS; X-RAYS;

EID: 84939885418     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-2101-8     Document Type: Article

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