Dysregulation of IRP1-Mediated Iron Metabolism Causes Gamma Ray-specific Radioresistance in Leukemia Cells

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Haro, Kurtis J ^a,b   Sheth, Aneesh ^a,b   Scheinberg, David A ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IRON REGULATORY PROTEIN 1; SHORT HAIRPIN RNA; STAUROSPORINE;

ALPHA RADIATION; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DEINOCOCCUS RADIODURANS; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; ENZYME METABOLISM; GAMMA RADIATION; GENE SEQUENCE; HUMAN; HUMAN CELL; IRON METABOLISM; LEUKEMIA CELL; LINEAR ENERGY TRANSFER; MYELOID LEUKEMIA; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RADIATION PROTECTION; RADIOSENSITIVITY; RNA INTERFERENCE;

ALPHA PARTICLES; CELL DEATH; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; DOSE-RESPONSE RELATIONSHIP, RADIATION; GAMMA RAYS; HUMANS; IRON; IRON REGULATORY PROTEIN 1; RADIATION TOLERANCE;

DEINOCOCCUS RADIODURANS; MAMMALIA;

EID: 84869123994     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048841     Document Type: Article

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