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Volumn 38, Issue 2, 2015, Pages 623-631

Arctigenin Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Rats

Author keywords

ALI; AMPK; arctigenin; LPS; NF B

Indexed keywords

AMP-ACTIVATED PROTEIN KINASE ALPHA1 PROTEIN, RAT; ANTIINFLAMMATORY AGENT; ARCTIGENIN; FURAN DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; I KAPPA B; IL1B PROTEIN, RAT; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIGNAN; LIPOPOLYSACCHARIDE; NF-KAPPAB INHIBITOR ALPHA; PEROXIDASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84939880877     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-9969-z     Document Type: Article
Times cited : (33)

References (41)
  • 1
    • 84872181149 scopus 로고    scopus 로고
    • The new definition for acute lung injury and acute respiratory distress syndrome: is there room for improvement?
    • PID: 23235543
    • Costa, E.L., and M.B. Amato. 2013. The new definition for acute lung injury and acute respiratory distress syndrome: is there room for improvement? Current Opinion in Critical Care 19(1): 16–23.
    • (2013) Current Opinion in Critical Care , vol.19 , Issue.1 , pp. 16-23
    • Costa, E.L.1    Amato, M.B.2
  • 2
    • 78651241847 scopus 로고    scopus 로고
    • Plasma protein levels are markers of pulmonary vascular permeability and degree of lung injury in critically ill patients with or at risk for acute lung injury/acute respiratory distress syndrome
    • COI: 1:CAS:528:DC%2BC3cXhs1Wjtb7L, PID: 21057316
    • van der Aman, J., M. Heijden, A. van Lingen, A.R. Girbes, G.P. van Nieuw Amerongen, V.W. van Hinsbergh, and A.B. Groeneveld. 2011. Plasma protein levels are markers of pulmonary vascular permeability and degree of lung injury in critically ill patients with or at risk for acute lung injury/acute respiratory distress syndrome. Critical Care Medicine 39(1): 89–97.
    • (2011) Critical Care Medicine , vol.39 , Issue.1 , pp. 89-97
    • van der Aman, J.1    Heijden, M.2    van Lingen, A.3    Girbes, A.R.4    van Nieuw Amerongen, G.P.5    van Hinsbergh, V.W.6    Groeneveld, A.B.7
  • 4
    • 78649970924 scopus 로고    scopus 로고
    • Glycyrrhizin treatment is associated with attenuation of lipopolysaccharide-induced acute lung injury by inhibiting cyclooxygenase-2 and inducible nitric oxide synthase expression
    • COI: 1:CAS:528:DC%2BC3cXhsFCqt7jF, PID: 21074783
    • Ni, Y.F., J.K. Kuai, Z.F. Lu, G.D. Yang, H.Y. Fu, J. Wang, F. Tian, X.L. Yan, Y.C. Zhao, Y.J. Wang, and T. Jiang. 2011. Glycyrrhizin treatment is associated with attenuation of lipopolysaccharide-induced acute lung injury by inhibiting cyclooxygenase-2 and inducible nitric oxide synthase expression. The Journal of Surgical Research 165(1): e29–35.
    • (2011) The Journal of Surgical Research , vol.165 , Issue.1 , pp. 29-35
    • Ni, Y.F.1    Kuai, J.K.2    Lu, Z.F.3    Yang, G.D.4    Fu, H.Y.5    Wang, J.6    Tian, F.7    Yan, X.L.8    Zhao, Y.C.9    Wang, Y.J.10    Jiang, T.11
  • 5
    • 77952482463 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice
    • PID: 20302656
    • Ni, Y.F., J. Wang, X.L. Yan, F. Tian, J.B. Zhao, Y.J. Wang, and T. Jiang. 2010. Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice. Respiratory Research 11: 33.
    • (2010) Respiratory Research , vol.11 , pp. 33
    • Ni, Y.F.1    Wang, J.2    Yan, X.L.3    Tian, F.4    Zhao, J.B.5    Wang, Y.J.6    Jiang, T.7
  • 6
    • 34347261987 scopus 로고    scopus 로고
    • Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies
    • COI: 1:CAS:528:DC%2BD2sXhs1WnsrY%3D, PID: 17173364
    • Luh, S.P., and C.H. Chiang. 2007. Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies. Journal of Zhejiang University. Science. B 8(1): 60–69.
    • (2007) Journal of Zhejiang University. Science. B , vol.8 , Issue.1 , pp. 60-69
    • Luh, S.P.1    Chiang, C.H.2
  • 7
    • 17144369537 scopus 로고    scopus 로고
    • Acute respiratory distress syndrome: update on the latest developments in basic and clinical research
    • PID: 16534329
    • Bosma, K., V. Fanelli, and V.M. Ranieri. 2005. Acute respiratory distress syndrome: update on the latest developments in basic and clinical research. Current Opinion in Anaesthesiology 18(2): 137–145.
    • (2005) Current Opinion in Anaesthesiology , vol.18 , Issue.2 , pp. 137-145
    • Bosma, K.1    Fanelli, V.2    Ranieri, V.M.3
  • 8
    • 0035109852 scopus 로고    scopus 로고
    • Neutrophil activation and acute lung injury
    • COI: 1:STN:280:DC%2BD3MzltVersA%3D%3D, PID: 11373504
    • Lee, W.L., and G.P. Downey. 2001. Neutrophil activation and acute lung injury. Current Opinion in Critical Care 7(1): 1–7.
    • (2001) Current Opinion in Critical Care , vol.7 , Issue.1 , pp. 1-7
    • Lee, W.L.1    Downey, G.P.2
  • 9
    • 77956063983 scopus 로고    scopus 로고
    • Preventive effects of valnemulin on lipopolysaccharide-induced acute lung injury in mice
    • COI: 1:CAS:528:DC%2BC3cXpvFemu7Y%3D, PID: 20221680
    • Chen, Z., X. Zhang, X. Chu, X. Zhang, K. Song, Y. Jiang, L. Yu, and X. Deng. 2010. Preventive effects of valnemulin on lipopolysaccharide-induced acute lung injury in mice. Inflammation 33(5): 306–314.
    • (2010) Inflammation , vol.33 , Issue.5 , pp. 306-314
    • Chen, Z.1    Zhang, X.2    Chu, X.3    Zhang, X.4    Song, K.5    Jiang, Y.6    Yu, L.7    Deng, X.8
  • 10
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • COI: 1:CAS:528:DyaK1MXotVyhtL0%3D, PID: 10602461
    • Pahl, H.L. 1999. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18(49): 6853–6866.
    • (1999) Oncogene , vol.18 , Issue.49 , pp. 6853-6866
    • Pahl, H.L.1
  • 11
    • 84855563615 scopus 로고    scopus 로고
    • Suppression of NF-kappaB pathway by crocetin contributes to attenuation of lipopolysaccharide-induced acute lung injury in mice
    • COI: 1:CAS:528:DC%2BC38Xks1Kltg%3D%3D, PID: 21925167
    • Yang, R., L. Yang, X. Shen, W. Cheng, B. Zhao, K.H. Ali, Z. Qian, and H. Ji. 2012. Suppression of NF-kappaB pathway by crocetin contributes to attenuation of lipopolysaccharide-induced acute lung injury in mice. European Journal of Pharmacology 674(2–3): 391–396.
    • (2012) European Journal of Pharmacology , vol.674 , Issue.2-3 , pp. 391-396
    • Yang, R.1    Yang, L.2    Shen, X.3    Cheng, W.4    Zhao, B.5    Ali, K.H.6    Qian, Z.7    Ji, H.8
  • 12
    • 79960038851 scopus 로고    scopus 로고
    • Anti-inflammatory activities of mogrosides from Momordica grosvenori in murine macrophages and a murine ear edema model
    • COI: 1:CAS:528:DC%2BC3MXnsFWit7c%3D, PID: 21631112
    • Di, R., M.T. Huang, and C.T. Ho. 2011. Anti-inflammatory activities of mogrosides from Momordica grosvenori in murine macrophages and a murine ear edema model. Journal of Agricultural and Food Chemistry 59(13): 7474–81.
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , Issue.13 , pp. 7474-7481
    • Di, R.1    Huang, M.T.2    Ho, C.T.3
  • 13
    • 77957913650 scopus 로고    scopus 로고
    • AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis
    • COI: 1:CAS:528:DC%2BC3cXhtlSmsbbL, PID: 20797389
    • Bai, A., A.G. Ma, M. Yong, C.R. Weiss, Y. Ma, Q. Guan, C.N. Bernstein, and Z. Peng. 2010. AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis. Biochemical Pharmacology 80(11): 1708–1717.
    • (2010) Biochemical Pharmacology , vol.80 , Issue.11 , pp. 1708-1717
    • Bai, A.1    Ma, A.G.2    Yong, M.3    Weiss, C.R.4    Ma, Y.5    Guan, Q.6    Bernstein, C.N.7    Peng, Z.8
  • 14
    • 21244437079 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis
    • COI: 1:CAS:528:DC%2BD2MXltlymsL0%3D
    • Nath, N., S. Giri, R. Prasad, M.L. Salem, A.K. Singh, and I. Singh. 2005. 5-Aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md.: 1950) 175(1): 566–574.
    • (2005) Journal of Immunology (Baltimore, Md. : 1950) , vol.175 , Issue.1 , pp. 566-574
    • Nath, N.1    Giri, S.2    Prasad, R.3    Salem, M.L.4    Singh, A.K.5    Singh, I.6
  • 17
    • 1642499162 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase
    • COI: 1:CAS:528:DC%2BD2cXpvVyjsA%3D%3D
    • Giri, S., N. Nath, B. Smith, B. Viollet, A.K. Singh, and I. Singh. 2004. 5-Aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 24(2): 479–87.
    • (2004) The Journal of Neuroscience : The Official Journal of the Society for Neuroscience , vol.24 , Issue.2 , pp. 479-487
    • Giri, S.1    Nath, N.2    Smith, B.3    Viollet, B.4    Singh, A.K.5    Singh, I.6
  • 18
    • 4143102621 scopus 로고    scopus 로고
    • Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits MAP kinases and AP-1 activation via potent MKK inhibition: the role in TNF-alpha inhibition
    • COI: 1:CAS:528:DC%2BD2cXmslehurs%3D, PID: 15313439
    • Cho, M.K., Y.P. Jang, Y.C. Kim, and S.G. Kim. 2004. Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits MAP kinases and AP-1 activation via potent MKK inhibition: the role in TNF-alpha inhibition. International Immunopharmacology 4(10–11): 1419–1429.
    • (2004) International Immunopharmacology , vol.4 , Issue.10-11 , pp. 1419-1429
    • Cho, M.K.1    Jang, Y.P.2    Kim, Y.C.3    Kim, S.G.4
  • 19
    • 63649103383 scopus 로고    scopus 로고
    • In vitro anti-inflammatory effects of arctigenin, a lignan from Arctium lappa L., through inhibition on iNOS pathway
    • COI: 1:CAS:528:DC%2BD1MXksVaitro%3D, PID: 19429312
    • Zhao, F., L. Wang, and K. Liu. 2009. In vitro anti-inflammatory effects of arctigenin, a lignan from Arctium lappa L., through inhibition on iNOS pathway. Journal of Ethnopharmacology 122(3): 457–462.
    • (2009) Journal of Ethnopharmacology , vol.122 , Issue.3 , pp. 457-462
    • Zhao, F.1    Wang, L.2    Liu, K.3
  • 21
    • 0035074976 scopus 로고    scopus 로고
    • Anti-inflammatory activity of cubebin, a lignan from the leaves of Zanthoxyllum naranjillo Griseb
    • COI: 1:CAS:528:DC%2BD3MXisF2ku7c%3D, PID: 11297863
    • Bastos, J.K., J.C. Carvalho, G.H. de Souza, A.H. Pedrazzi, and S.J. Sarti. 2001. Anti-inflammatory activity of cubebin, a lignan from the leaves of Zanthoxyllum naranjillo Griseb. Journal of Ethnopharmacology 75(2–3): 279–282.
    • (2001) Journal of Ethnopharmacology , vol.75 , Issue.2-3 , pp. 279-282
    • Bastos, J.K.1    Carvalho, J.C.2    de Souza, G.H.3    Pedrazzi, A.H.4    Sarti, S.J.5
  • 22
    • 0036213741 scopus 로고    scopus 로고
    • Arctigenin protects cultured cortical neurons from glutamate-induced neurodegeneration by binding to kainate receptor
    • COI: 1:CAS:528:DC%2BD38XivV2gu7g%3D, PID: 11948668
    • Jang, Y.P., S.R. Kim, Y.H. Choi, J. Kim, S.G. Kim, G.J. Markelonis, T.H. Oh, and Y.C. Kim. 2002. Arctigenin protects cultured cortical neurons from glutamate-induced neurodegeneration by binding to kainate receptor. Journal of Neuroscience Research 68(2): 233–240.
    • (2002) Journal of Neuroscience Research , vol.68 , Issue.2 , pp. 233-240
    • Jang, Y.P.1    Kim, S.R.2    Choi, Y.H.3    Kim, J.4    Kim, S.G.5    Markelonis, G.J.6    Oh, T.H.7    Kim, Y.C.8
  • 23
    • 0034938119 scopus 로고    scopus 로고
    • Neuroprotective dibenzylbutyrolactone lignans of Torreya nucifera
    • COI: 1:CAS:528:DC%2BD3MXlsVKhu70%3D, PID: 11488466
    • Jang, Y.P., S.R. Kim, and Y.C. Kim. 2001. Neuroprotective dibenzylbutyrolactone lignans of Torreya nucifera. Planta Medica 67(5): 470–472.
    • (2001) Planta Medica , vol.67 , Issue.5 , pp. 470-472
    • Jang, Y.P.1    Kim, S.R.2    Kim, Y.C.3
  • 24
    • 0034730949 scopus 로고    scopus 로고
    • Anti-tumor-promoting activity of lignans from the aerial part of Saussurea medusa
    • COI: 1:CAS:528:DC%2BD3cXlsFCisr0%3D, PID: 10940509
    • Takasaki, M., T. Konoshima, K. Komatsu, H. Tokuda, and H. Nishino. 2000. Anti-tumor-promoting activity of lignans from the aerial part of Saussurea medusa. Cancer Letters 158(1): 53–59.
    • (2000) Cancer Letters , vol.158 , Issue.1 , pp. 53-59
    • Takasaki, M.1    Konoshima, T.2    Komatsu, K.3    Tokuda, H.4    Nishino, H.5
  • 25
    • 0035185314 scopus 로고    scopus 로고
    • Potent inhibition of lipopolysaccharide-inducible nitric oxide synthase expression by dibenzylbutyrolactone lignans through inhibition of I-kappaBalpha phosphorylation and of p65 nuclear translocation in macrophages
    • COI: 1:CAS:528:DC%2BD38Xjt1yksg%3D%3D, PID: 11789661
    • Cho, M.K., J.W. Park, Y.P. Jang, Y.C. Kim, and S.G. Kim. 2002. Potent inhibition of lipopolysaccharide-inducible nitric oxide synthase expression by dibenzylbutyrolactone lignans through inhibition of I-kappaBalpha phosphorylation and of p65 nuclear translocation in macrophages. International Immunopharmacology 2(1): 105–116.
    • (2002) International Immunopharmacology , vol.2 , Issue.1 , pp. 105-116
    • Cho, M.K.1    Park, J.W.2    Jang, Y.P.3    Kim, Y.C.4    Kim, S.G.5
  • 26
    • 78249276479 scopus 로고    scopus 로고
    • Dibenzylbutyrolactone lignans from Forsythia koreana fruits attenuate lipopolysaccharide-induced inducible nitric oxide synthetase and cyclooxygenase-2 expressions through activation of nuclear factor-kappab and mitogen-activated protein kinase in RAW264.7 cells
    • COI: 1:CAS:528:DC%2BC3cXhs1artr3L
    • Lee, J.Y., B.J. Cho, T.W. Park, B.E. Park, S.J. Kim, S.S. Sim, and C.J. Kim. 2010. Dibenzylbutyrolactone lignans from Forsythia koreana fruits attenuate lipopolysaccharide-induced inducible nitric oxide synthetase and cyclooxygenase-2 expressions through activation of nuclear factor-kappab and mitogen-activated protein kinase in RAW264.7 cells. Biological & Pharmaceutical Bulletin 33(11): 1847–1853.
    • (2010) Biological & Pharmaceutical Bulletin , vol.33 , Issue.11 , pp. 1847-1853
    • Lee, J.Y.1    Cho, B.J.2    Park, T.W.3    Park, B.E.4    Kim, S.J.5    Sim, S.S.6    Kim, C.J.7
  • 28
    • 84878580765 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of arctigenin ester and ether derivatives as activators of AMPK
    • COI: 1:CAS:528:DC%2BC3sXnslCntLw%3D
    • Shen, S., J. Zhuang, Y. Chen, M. Lei, J. Chen, X. Shen, and L. Hu. 2013. Synthesis and biological evaluation of arctigenin ester and ether derivatives as activators of AMPK. Bioorganic & Medicinal Chemistry 21(13): 3882–3893.
    • (2013) Bioorganic & Medicinal Chemistry , vol.21 , Issue.13 , pp. 3882-3893
    • Shen, S.1    Zhuang, J.2    Chen, Y.3    Lei, M.4    Chen, J.5    Shen, X.6    Hu, L.7
  • 29
    • 55249120522 scopus 로고    scopus 로고
    • Fructose-1,6-diphosphate attenuates acute lung injury induced by lipopolysaccharide in mice
    • COI: 1:CAS:528:DC%2BD1cXhtlGht7bN, PID: 18824250
    • Yin, H., X.B. Jin, Q. Gong, H. Yang, L.Y. Hu, F.L. Gong, and J.Y. Zhu. 2008. Fructose-1,6-diphosphate attenuates acute lung injury induced by lipopolysaccharide in mice. International Immunopharmacology 8(13–14): 1842–1847.
    • (2008) International Immunopharmacology , vol.8 , Issue.13-14 , pp. 1842-1847
    • Yin, H.1    Jin, X.B.2    Gong, Q.3    Yang, H.4    Hu, L.Y.5    Gong, F.L.6    Zhu, J.Y.7
  • 32
    • 70350754327 scopus 로고    scopus 로고
    • Protective effect of florfenicol on acute lung injury induced by lipopolysaccharide in mice
    • COI: 1:CAS:528:DC%2BD1MXhtlygs77E, PID: 19765678
    • Zhang, X., K. Song, H. Xiong, H. Li, X. Chu, and X. Deng. 2009. Protective effect of florfenicol on acute lung injury induced by lipopolysaccharide in mice. International Immunopharmacology 9(13–14): 1525–1529.
    • (2009) International Immunopharmacology , vol.9 , Issue.13-14 , pp. 1525-1529
    • Zhang, X.1    Song, K.2    Xiong, H.3    Li, H.4    Chu, X.5    Deng, X.6
  • 33
    • 33646518813 scopus 로고    scopus 로고
    • Pharmacotherapy of acute lung injury and the acute respiratory distress syndrome
    • PID: 16672636
    • Cepkova, M., and M.A. Matthay. 2006. Pharmacotherapy of acute lung injury and the acute respiratory distress syndrome. Journal of Intensive Care Medicine 21(3): 119–143.
    • (2006) Journal of Intensive Care Medicine , vol.21 , Issue.3 , pp. 119-143
    • Cepkova, M.1    Matthay, M.A.2
  • 34
    • 18244390487 scopus 로고    scopus 로고
    • Myeloperoxidase: friend and foe
    • COI: 1:CAS:528:DC%2BD2MXktFentLw%3D, PID: 15689384
    • Klebanoff, S.J. 2005. Myeloperoxidase: friend and foe. Journal of Leukocyte Biology 77(5): 598–625.
    • (2005) Journal of Leukocyte Biology , vol.77 , Issue.5 , pp. 598-625
    • Klebanoff, S.J.1
  • 35
    • 1142299409 scopus 로고    scopus 로고
    • Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome
    • COI: 1:CAS:528:DC%2BD2cXhvVKjtr4%3D, PID: 14743496
    • Bhatia, M., and S. Moochhala. 2004. Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome. The Journal of Pathology 202(2): 145–156.
    • (2004) The Journal of Pathology , vol.202 , Issue.2 , pp. 145-156
    • Bhatia, M.1    Moochhala, S.2
  • 37
    • 33748312129 scopus 로고    scopus 로고
    • Regeneration of the endothelium as a novel therapeutic strategy for acute lung injury
    • COI: 1:CAS:528:DC%2BD28Xps1Sgs70%3D, PID: 16955131
    • Minamino, T., and I. Komuro. 2006. Regeneration of the endothelium as a novel therapeutic strategy for acute lung injury. The Journal of Clinical Investigation 116(9): 2316–2319.
    • (2006) The Journal of Clinical Investigation , vol.116 , Issue.9 , pp. 2316-2319
    • Minamino, T.1    Komuro, I.2
  • 38
    • 0036045390 scopus 로고    scopus 로고
    • Cytokine modulation in sepsis and septic shock
    • COI: 1:CAS:528:DC%2BD38Xmt12htbg%3D, PID: 12150702
    • Zanotti, S., A. Kumar, and A. Kumar. 2002. Cytokine modulation in sepsis and septic shock. Expert Opinion on Investigational Drugs 11(8): 1061–1075.
    • (2002) Expert Opinion on Investigational Drugs , vol.11 , Issue.8 , pp. 1061-1075
    • Zanotti, S.1    Kumar, A.2    Kumar, A.3
  • 39
    • 0034913364 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor therapy in sepsis: update on clinical trials and lessons learned
    • 7 Suppl COI: 1:STN:280:DC%2BD3MzptVyrsw%3D%3D, PID: 11445746
    • Reinhart, K., and W. Karzai. 2001. Anti-tumor necrosis factor therapy in sepsis: update on clinical trials and lessons learned. Critical Care Medicine 29(7 Suppl): S121–125.
    • (2001) Critical Care Medicine , vol.29 , pp. 121-125
    • Reinhart, K.1    Karzai, W.2
  • 41
    • 58849115949 scopus 로고    scopus 로고
    • Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype
    • COI: 1:CAS:528:DC%2BD1cXhsVCktr3M
    • Sag, D., D. Carling, R.D. Stout, and J. Suttles. 2008. Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype. Journal of Immunology (Baltimore, Md.: 1950) 181(12): 8633–8641.
    • (2008) Journal of Immunology (Baltimore, Md. : 1950) , vol.181 , Issue.12 , pp. 8633-8641
    • Sag, D.1    Carling, D.2    Stout, R.D.3    Suttles, J.4


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