Decoupling the contribution of surface energy and surface area on the cohesion of pharmaceutical powders

Pharmaceutical Research

Volumn 32, Issue 1, 2015, Pages 248-259

  Shah, Umang V ^a   Olusanmi, Dolapo ^b   Narang, Ajit S ^b   Hussain, Munir A ^b   Tobyn, Michael J ^b   Hinder, Steve J ^c   Heng, Jerry Y Y ^a  

^a Imperial College London South Kensington Campus   (United Kingdom)

^b BRISTOL MYERS SQUIBB   (United States)

^c UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

cohesion; milling; silanisation; surface area; surface energy

Indexed keywords

DICHLORODIMETHYLSILANE; EXCIPIENT; MEFENAMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; POWDER; SILANE DERIVATIVE;

CHEMISTRY; CRYSTALLIZATION; PARTICLE SIZE; PHARMACEUTICS; POWDER; PROCEDURES; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; X RAY PHOTOELECTRON SPECTROSCOPY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CRYSTALLIZATION; EXCIPIENTS; MEFENAMIC ACID; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; PHOTOELECTRON SPECTROSCOPY; POWDERS; SILANES; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 84939877104     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-014-1459-3     Document Type: Article

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