Lentiviral-mediated short hairpin RNA knockdown of MTDH inhibits cell growth and induces apoptosis by regulating the PTEN/AKT pathway in hepatocellular carcinoma

International Journal of Molecular Sciences

Volumn 16, Issue 8, 2015, Pages 19419-19432

  Li, Wen Fang ^a   Ou, Qin ^b   Dai, Hang ^a   Liu, Chang An ^a,c  

^a THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

^c State Key Lab of Ultrasound Eng in Med Co Founded by Chongqing and the Min of Sci and Technol   (China)

Author keywords

Apoptosis; Growth; Hepatocellular carcinoma; Metadherin

Indexed keywords

CELL SURFACE PROTEIN; CHOLECYSTOKININ OCTAPEPTIDE; MESSENGER RNA; METADHERIN; PHOSPHATIDYLINOSITOL 3, 4, 5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN P53; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; MTDH PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PTEN PROTEIN, HUMAN; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER SURVIVAL; CARCINOGENICITY; CELL VIABILITY; COLONY FORMATION; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; GENE SILENCING; GENE THERAPY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LENTIVIRINAE; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH; TUMOR VOLUME; WESTERN BLOTTING; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; GENETICS; HEP-G2 CELL LINE; LIVER; LIVER NEOPLASMS; METABOLISM; PATHOLOGY; RNAI THERAPEUTICS; SIGNAL TRANSDUCTION;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL ADHESION MOLECULES; CELL PROLIFERATION; HEP G2 CELLS; HUMANS; LENTIVIRUS; LIVER; LIVER NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA, SMALL INTERFERING; RNAI THERAPEUTICS; SIGNAL TRANSDUCTION;

EID: 84939832692     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160819419     Document Type: Article

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