In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 33, 2015, Pages 10515-10520

  Takihara, Yuji ^a,b   Inatani, Masaru ^a,b   Eto, Kei ^c,d   Inoue, Toshihiro ^b   Kreymerman, Alexander ^e   Miyake, Seiji ^a   Ueno, Shinji ^f   Nagaya, Masatoshi ^f   Nakanishi, Ayami ^f   Iwao, Keiichiro ^b   Takamura, Yoshihiro ^a   Sakamoto, Hirotaka ^g   Satoh, Keita ^g   Kondo, Mineo ^h   Sakamoto, Tatsuya ^g   Goldberg, Jeffrey L ^e   Nabekura, Junichi ^c,d   Tanihara, Hidenobu ^b  

^a UNIVERSITY OF FUKUI   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^d GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^e UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^f NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g OKAYAMA UNIVERSITY   (Japan)

^h MIE UNIVERSITY   (Japan)

Author keywords

Aging; In vivo imaging; Mammalian CNS; Mitochondrial axonal transport; Neurodegeneration

Indexed keywords

ADULT; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; GLAUCOMA; IN VIVO STUDY; MITOCHONDRION; MOUSE; NERVE CELL NECROSIS; NERVE FIBER; NERVE FIBER TRANSPORT; NEUROIMAGING; NONHUMAN; PRIORITY JOURNAL; RETINA GANGLION CELL; ANIMAL; AXON; BAGG ALBINO MOUSE; C57BL MOUSE; CYTOLOGY; DISEASE MODEL; FEMALE; MALE; OPTIC NERVE; PATHOLOGY; PATHOPHYSIOLOGY; PHOTON; PHYSIOLOGY; RETINA; SCLERA; THREE DIMENSIONAL IMAGING; TIME FACTOR; TRANSPORT AT THE CELLULAR LEVEL;

MAMMALIA; MUS;

AGING; ANIMALS; AXONAL TRANSPORT; AXONS; BIOLOGICAL TRANSPORT; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; FEMALE; GLAUCOMA; IMAGING, THREE-DIMENSIONAL; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MITOCHONDRIA; OPTIC NERVE; PHOTONS; RETINA; RETINAL GANGLION CELLS; SCLERA; TIME FACTORS;

EID: 84939832226     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1509879112     Document Type: Article

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