Neonatal serotonin reuptake inhibition reduces hypercaloric diet effects on fat mass and hypothalamic gene expression in adult rats

International Journal of Developmental Neuroscience

Volumn 46, Issue , 2015, Pages 76-81

  Galindo, Lígia Cristina Monteiro ^a   Barros, Manuella da Luz Duarte ^a   Pinheiro, Isabeli Lins ^a   Santana, Ricardo Vinicius de Carvalho ^a   Matos, Rhowena Jane Barbosa de ^a   Leandro, Carol Góis ^a   Souza, Sandra Lopes de ^a   Manhães de Castro, Raul ^a  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

Adipose tissue; Developmental plasticity; Food intake; Hypercaloric diet; Rats; Serotonin; SSRI

Indexed keywords

CHOLESTEROL; FLUOXETINE; NEUROPEPTIDE Y; SEROTONIN 1B RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN RECEPTOR; TRIACYLGLYCEROL; PROOPIOMELANOCORTIN; SEROTONIN; SEROTONIN UPTAKE INHIBITOR;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME INHIBITION; FAT MASS; FEEDING BEHAVIOR; FEMALE; FOOD INTAKE; GENE; GENE EXPRESSION; HYPOTHALAMUS; LIPID DIET; MALE; NEWBORN; NEWBORN PERIOD; NONHUMAN; NPY GENE; POMC GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WHITE ADIPOSE TISSUE; ADIPOSE TISSUE; ADVERSE EFFECTS; AGE; ANIMAL; BLOOD; DIET; DRUG EFFECTS; EATING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; PREGNANCY; WISTAR RAT;

ANIMALIA; RATTUS;

ADIPOSE TISSUE; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; CHOLESTEROL; DIET; EATING; FEMALE; FLUOXETINE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HYPOTHALAMUS; MALE; NEUROPEPTIDE Y; PREGNANCY; PRO-OPIOMELANOCORTIN; RATS; RATS, WISTAR; SEROTONIN; SEROTONIN UPTAKE INHIBITORS; TRIGLYCERIDES;

EID: 84939782302     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2015.07.004     Document Type: Article

References (35)

1. Alsio J., et al. Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats. Neuroscience 2010, 171(3):779-787.
2. Azmitia E.C. Modern views on an ancient chemical: serotonin effects on cell proliferation, maturation, and apoptosis. Brain Res. Bull. 2001, 56(5):413-424.
3. Baumann P., Rochat B. Comparative pharmacokinetics of selective serotonin reuptake inhibitors a look behind the mirror. Int. Clin. Psychopharmacol. 1995, 10(Suppl 1):15-21.
4. Bieswal F., et al. The importance of catch-up growth after early malnutrition for the programming of obesity in male rat. Obesity (Silver Spring) 2006, 14(8):1330-1343.
5. Bonnin A., et al. Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development. Neuroscience 2006, 141(2):781-794.
6. Bouret S.G., et al. Hypothalamic neural projections are permanently disrupted in diet-induced obese rats. Cell Metab. 2008, 7(2):179-185.
7. Deiro T.C., et al. Neonatal administration of citalopram delays somatic maturation in rats. Braz. J. Med. Biol. Res. 2004, 37(10):1503-1509.
8. Deiro T.C., et al. Sertraline delays the somatic growth and reflex ontogeny in neonate rats. Physiol. Behav. 2006, 87(2):338-344.
9. Donovan M.H., Tecott L.H. Serotonin and the regulation of mammalian energy balance. Front Neurosci. 2013, 7:36.
10. Erlanson-Albertsson C. How palatable food disrupts appetite regulation. Basic Clin. Pharmacol. Toxicol. 2005, 97(2):61-73.
11. Foltin R.W. Consumption of palatable food decreases the anorectic effects of serotonergic, but not dopaminergic drugs in baboons. Physiol. Behav. 2011, 103(5):493-500.
12. Gluckman P.D., et al. Metabolic plasticity during mammalian development is directionally dependent on early nutritional status. Proc. Natl. Acad. Sci. U.S.A. 2007, 104(31):12796-12800.
13. Heisler L.K., et al. Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron 2006, 51(2):239-249.
14. Heisler L.K., et al. Central serotonin and melanocortin pathways regulating energy homeostasis. Ann. N.Y. Acad. Sci. 2003, 994:169-174.
15. Krishnan V., Nestler E.J. The molecular neurobiology of depression. Nature 2008, 455(7215):894-902.
16. Kummet G.J., et al. Neonatal SSRI exposure programs a hypermetabolic state in adult mice. J. Nutr. Metab. 2012, 2012:431574.
17. Lauzurica N., et al. Hypophagia and induction of serotonin transporter gene expression in raphe nuclei of male and female rats after short-term fluoxetine treatment. J. Physiol. Biochem. 2013, 69(1):69-74.
18. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25(4):402-408.
19. Lopes de Souza S., et al. Perinatal protein restriction reduces the inhibitory action of serotonin on food intake. Eur. J. Neurosci. 2008, 27(6):1400-1408.
20. Low F.M., P.D. Gluckman M.A. Hanson Developmental plasticity and epigenetic mechanisms underpinning metabolic and cardiovascular diseases. Epigenomics 2011, 3(3):279-294.
21. Maciag D., et al. Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry. Neuropsychopharmacology 2006, 31(1):47-57.
22. Manhaes de Castro R., et al. Reduction of intraspecific aggression in adult rats by neonatal treatment with a selective serotonin reuptake inhibitor. Braz. J. Med. Biol. Res. 2001, 34(1):121-124.
23. Manjarrez G., et al. Serotonergic receptors in the brain of in utero undernourished rats. Int. J. Dev. Neurosci. 2003, 21(5):283-289.
24. McNamara I.M., et al. Further studies in the developmental hyperserotonemia model (DHS) of autism: social, behavioral and peptide changes. Brain Res. 2008, 1189:203-214.
25. Mendes-da-Silva C., et al. Neonatal treatment with fluoxetine reduces depressive behavior induced by forced swim in adult rats. Arq. Neuropsiquiatr. 2002, 60(4):928-931.
26. Nulman I., et al. Child development following exposure to tricyclic antidepressants or fluoxetine throughout fetal life: a prospective, controlled study. Am. J. Psychiatry 2002, 159(11):1889-1895.
27. Oberlander T.F., Gingrich J.A., Ansorge M.S. Sustained neurobehavioral effects of exposure to SSRI antidepressants during development: molecular to clinical evidence. Clin. Pharmacol. Ther. 2009, 86(6):672-677.
28. Orozco-Solis R., et al. Perinatal undernutrition-induced obesity is independent of the developmental programming of feeding. Physiol. Behav. 2009, 96(3):481-492.
29. Rodgers R.J., Holch P., Tallett A.J. Behavioural satiety sequence (BSS): separating wheat from chaff in the behavioural pharmacology of appetite. Pharmacol. Biochem. Behav. 2010, 97(1):3-14.
30. Silva C.M., et al. Postnatal fluoxetine treatment affects the development of serotonergic neurons in rats. Neurosci. Lett. 2010, 483(3):179-183.
31. Stunes A.K., et al. Adipocytes express a functional system for serotonin synthesis, reuptake and receptor activation. Diabetes Obes. Metab. 2011, 13(6):551-558.
32. Valassi E., Scacchi M., Cavagnini F. Neuroendocrine control of food intake. Nutr. Metab. Cardiovasc. Dis. 2008, 18(2):158-168.
33. Watanabe H., Rose M.T., Aso H. Role of peripheral serotonin in glucose and lipid metabolism. Curr. Opin. Lipidol. 2011, 22(3):186-191.
34. West-Eberhard M.J. Alternative adaptations, speciation, and phylogeny (a review). Proc. Natl. Acad. Sci. U.S.A. 1986, 83(5):1388-1392.
35. West-Eberhard M.J. Phenotypic accommodation: adaptive innovation due to developmental plasticity. J. Exp. Zool. B Mol. Dev. Evol. 2005, 304(6):610-618.