Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats

Neuroscience

Volumn 171, Issue 3, 2010, Pages 779-787

  Alsio J ^a   Olszewski, P K ^a,b   Norback A H ^a   Gunnarsson, Z E A ^a   Levine, A S ^b   Pickering, C ^a,c   Schioth H B ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b University of Minnesota   (United States)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Caudate putamen; Dietary fat; Dietary sugar; Obesity prone phenotype; Opioid receptors

Indexed keywords

DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; MESSENGER RNA; MU OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE DIET; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE RESISTANCE; DOPAMINERGIC SYSTEM; FOOD INTAKE; GENE EXPRESSION REGULATION; LIPID DIET; LONG TERM EXPOSURE; MALE; NONHUMAN; NUCLEUS ACCUMBENS; OBESITY; PALATABILITY; PHENOTYPE; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WEIGHT GAIN;

ANIMALS; APPETITE REGULATION; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EATING; MALE; NUCLEUS ACCUMBENS; OBESITY; PHENOTYPE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; TIME FACTORS; WEIGHT GAIN;

EID: 78349308944     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.09.046     Document Type: Article

References (50)

1. Annerbrink K., Westberg L., Nilsson S., Rosmond R., Holm G., Eriksson E. Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men. Metab: Clin Exp 2008, 57:708-711.
2. Avena N.M., Rada P., Hoebel B.G. Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake. Neurosci Biobehav Rev 2008, 32:20-39.
3. Chandler P.C., Viana J.B., Oswald K.D., Wauford P.K., Boggiano M.M. Feeding response to melanocortin agonist predicts preference for and obesity from a high-fat diet. Physiol Behav 2005, 85:221-230.
4. Colantuoni C., Rada P., McCarthy J., Patten C., Avena N.M., Chadeayne A., Hoebel B.G. Evidence that intermittent, excessive sugar intake causes endogenous opioid dependence. Obes Res 2002, 10:478-488.
5. Comings D.E., Flanagan S.D., Dietz G., Muhleman D., Knell E., Gysin R. The dopamine D2 receptor (DRD2) as a major gene in obesity and height. Biochem Med Metab Biol 1993, 50:176-185.
6. Davis J.F., Tracy A.L., Schurdak J.D., Tschop M.H., Lipton J.W., Clegg D.J., Benoit S.C. Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat. Behav Neurosci 2008, 122:1257-1263.
7. Di Chiara G., Imperato A. Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats. J Pharmacol Exp Ther 1988, 244:1067-1080.
8. Dreher J.C., Kohn P., Kolachana B., Weinberger D.R., Berman K.F. Variation in dopamine genes influences responsivity of the human reward system. Proc Natl Acad Sci U S A 2009, 106:617-622.
9. El-Ghundi M., O'Dowd B.F., Erclik M., George S.R. Attenuation of sucrose reinforcement in dopamine D1 receptor deficient mice. Eur J Neurosci 2003, 17:851-862.
10. Epstein L.H., Jaroni J.L., Paluch R.A., Leddy J.J., Vahue H.E., Hawk L., Wileyto E.P., Shields P.G., Lerman C. Dopamine transporter genotype as a risk factor for obesity in African-American smokers. Obes Res 2002, 10:1232-1240.
11. Everitt B.J., Robbins T.W. Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci 2005, 8:1481-1489.
12. Geiger B.M., Haburcak M., Avena N.M., Moyer M.C., Hoebel B.G., Pothos E.N. Deficits of mesolimbic dopamine neurotransmission in rat dietary obesity. Neuroscience 2009, 159:1193-1199.
13. Hajnal A., De Jonghe B.C., Covasa M. Dopamine D2 receptors contribute to increased avidity for sucrose in obese rats lacking CCK-1 receptors. Neuroscience 2007, 148:584-592.
14. Hajnal A., Margas W.M., Covasa M. Altered dopamine D2 receptor function and binding in obese OLETF rat. Brain Res Bull 2008, 75:70-76.
15. Hamdi A., Porter J., Prasad C. Decreased striatal D2 dopamine receptors in obese Zucker rats: changes during aging. Brain Res 1992, 589:338-340.
16. Huang X.F., Yu Y., Zavitsanou K., Han M., Storlien L. Differential expression of dopamine D2 and D4 receptor and tyrosine hydroxylase mRNA in mice prone, or resistant, to chronic high-fat diet-induced obesity. Brain Res Mol Brain Res 2005, 135:150-161.
17. Huang X.F., Zavitsanou K., Huang X., Yu Y., Wang H., Chen F., Lawrence A.J., Deng C. Dopamine transporter and D2 receptor binding densities in mice prone or resistant to chronic high fat diet-induced obesity. Behav Brain Res 2006, 175:415-419.
18. Jenkinson C.P., Hanson R., Cray K., Wiedrich C., Knowler W.C., Bogardus C., Baier L. Association of dopamine D2 receptor polymorphisms Ser311Cys and TaqIA with obesity or type 2 diabetes mellitus in Pima Indians. Int J Obes Relat Metab Disord 2000, 24:1233-1238.
19. Johnson P.M., Kenny P.J. Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats. Nat Neurosci 2010, 13:635-641.
20. Kelley A.E., Bless E.P., Swanson C.J. Investigation of the effects of opiate antagonists infused into the nucleus accumbens on feeding and sucrose drinking in rats. J Pharmacol Exp Ther 1996, 278:1499-1507.
21. Kuo D.Y. Co-administration of dopamine D1 and D2 agonists additively decreases daily food intake, body weight and hypothalamic neuropeptide Y level in rats. J Biomed Sci 2002, 9:126-132.
22. la Fleur S.E., Vanderschuren L.J., Luijendijk M.C., Kloeze B.M., Tiesjema B., Adan R.A. A reciprocal interaction between food-motivated behavior and diet-induced obesity. Int J Obes 2007, 31:1286-1294.
23. la Fleur S.E., van Rozen A.J., Luijendijk M.C., Groeneweg F., Adan R.A. A free-choice high-fat high-sugar diet induces changes in arcuate neuropeptide expression that support hyperphagia. Int J Obes 2010, 34:537-546.
24. Lenard N.R., Zheng H., Berthoud H.R. Chronic suppression of mu-opioid receptor signaling in the nucleus accumbens attenuates development of diet-induced obesity in rats. Int J Obes 2010, 34:1001-1010.
25. Levin B.E., Dunn-Meynell A.A., Balkan B., Keesey R.E. Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats. Am J Physiol 1997, 273:R725-R730.
26. Levin B.E., Magnan C., Migrenne S., Chua S.C., Dunn-Meynell A.A. F-DIO obesity-prone rat is insulin resistant before obesity onset. Am J Physiol 2005, 289:R704-R711.
27. Li Y., South T., Han M., Chen J., Wang R., Huang X.F. High-fat diet decreases tyrosine hydroxylase mRNA expression irrespective of obesity susceptibility in mice. Brain Res 2009, 1268:181-189.
28. Lindblom J., Johansson A., Holmgren A., Grandin E., Nedergard C., Fredriksson R., Schioth H.B. Increased mRNA levels of tyrosine hydroxylase and dopamine transporter in the VTA of male rats after chronic food restriction. Eur J Neurosci 2006, 23:180-186.
29. Neovius M., Janson A., Rossner S. Prevalence of obesity in Sweden. Obes Rev 2006, 7:1-3.
30. Ogden C.L., Carroll M.D., Curtin L.R., McDowell M.A., Tabak C.J., Flegal K.M. Prevalence of overweight and obesity in the United States, 19992004. JAMA 2006, 295:1549-1555.
31. Palmiter R.D. Dopamine signaling in the dorsal striatum is essential for motivated behaviors: lessons from dopamine-deficient mice. Ann NY Acad Sci 2008, 1129:35-46.
32. Pickering C., Alsio J., Hulting A.L., Schioth H.B. Withdrawal from free-choice high-fat high-sugar diet induces craving only in obesity-prone animals. Psychopharmacology 2009, 204:431-443.
33. Rennie K.L., Jebb S.A. Prevalence of obesity in Great Britain. Obes Rev 2005, 6:11-12.
34. Small D.M., Jones-Gotman M., Dagher A. Feeding-induced dopamine release in dorsal striatum correlates with meal pleasantness ratings in healthy human volunteers. Neuroimage 2003, 19:1709-1715.
35. South T., Huang X.F. High-fat diet exposure increases dopamine D2 receptor and decreases dopamine transporter receptor binding density in the nucleus accumbens and caudate putamen of mice. Neurochem Res 2008, 33:598-605.
36. Spanagel R., Herz A., Shippenberg T.S. The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo] microdialysis study. J Neurochem 1990, 55:1734-1740.
37. Spanagel R., Herz A., Shippenberg T.S. Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proc Natl Acad Sci U S A 1992, 89:2046-2050.
38. Stice E., Spoor S., Bohon C., Small D.M. Relation between obesity and blunted striatal response to food is moderated by TaqIA A1 allele. Science 2008, 322:449-452.
39. Stice E., Spoor S., Bohon C., Veldhuizen M.G., Small D.M. Relation of reward from food intake and anticipated food intake to obesity: a functional magnetic resonance imaging study. J Abnorm Psychol 2008, 117:924-935.
40. Stice E., Spoor S., Ng J., Zald D.H. Relation of obesity to consummatory and anticipatory food reward. Physiol Behav 2009, 97:551-560.
41. Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002, 3. RESEARCH0034.
42. Volkow N.D., Fowler J.S., Wang G.J., Baler R., Telang F. Imaging dopamine's role in drug abuse and addiction. Neuropharmacology 2008, 56:3-8.
43. Volkow N.D., Fowler J.S., Wang G.J., Swanson J.M. Dopamine in drug abuse and addiction: results from imaging studies and treatment implications. Mol Psychiatry 2004, 9:557-569.
44. Volkow N.D., Wang G.J., Fowler J.S., Logan J., Jayne M., Franceschi D., Wong C., Gatley S.J., Gifford A.N., Ding Y.S., Pappas N. "Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect. Synapse (NY) 2002, 44:175-180.
45. Volkow N.D., Wang G.J., Telang F., Fowler J.S., Thanos P.K., Logan J., Alexoff D., Ding Y.S., Wong C., Ma Y., Pradhan K. Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors. Neuroimage 2008, 42:1537-1543.
46. Volkow N.D., Wise R.A. How can drug addiction help us understand obesity?. Nat Neurosci 2005, 8:555-560.
47. Wang J., Alexander J.T., Zheng P., Yu H.J., Dourmashkin J., Leibowitz S.F. Behavioral and endocrine traits of obesity-prone and obesity-resistant rats on macronutrient diets. Am J Physiol 1998, 274:E1057-E1066.
48. Wang G.J., Volkow N.D., Logan J., Pappas N.R., Wong C.T., Zhu W., Netusil N., Fowler J.S. Brain dopamine and obesity. Lancet 2001, 357:354-357.
49. Wise R.A. Roles for nigrostriatal-not just mesocorticolimbic-dopamine in reward and addiction. Trends Neurosci 2009, 32:517-524.
50. Zhang M., Gosnell B.A., Kelley A.E. Intake of high-fat food is selectively enhanced by mu opioid receptor stimulation within the nucleus accumbens. J Pharmacol Exp Ther 1998, 285:908-914.