-
1
-
-
0032480808
-
Structural determinants of the bifunctional corn Hageman factor inhibitor: X-ray crystal structure at 1.95 A resolution
-
Behnke, C. A., Yee, V. C., Trong, I. L., Pedersen, L. C., Stenkamp, R. E., Kim, S. S., Reeck, G. R., and Teller, D. C. (1998) Structural determinants of the bifunctional corn Hageman factor inhibitor: x-ray crystal structure at 1.95 A resolution Biochemistry 37, 15277-15288
-
(1998)
Biochemistry
, vol.37
, pp. 15277-15288
-
-
Behnke, C.A.1
Yee, V.C.2
Trong, I.L.3
Pedersen, L.C.4
Stenkamp, R.E.5
Kim, S.S.6
Reeck, G.R.7
Teller, D.C.8
-
2
-
-
0021267818
-
Amino acid sequence and secondary structural analysis of the corn inhibitor of trypsin and activated Hageman Factor
-
Mahoney, W. C., Hermodson, M. A., Jones, B., Powers, D. D., Corfman, R. S., and Reeck, G. R. (1984) Amino acid sequence and secondary structural analysis of the corn inhibitor of trypsin and activated Hageman Factor J. Biol. Chem. 259, 8412-8416
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 8412-8416
-
-
Mahoney, W.C.1
Hermodson, M.A.2
Jones, B.3
Powers, D.D.4
Corfman, R.S.5
Reeck, G.R.6
-
3
-
-
84907867397
-
The effect of corn trypsin inhibitor and inhibiting antibodies for FXIa and FXIIa on coagulation of plasma and whole blood
-
Hansson, K. M., Nielsen, S., Elg, M., and Deinum, J. (2014) The effect of corn trypsin inhibitor and inhibiting antibodies for FXIa and FXIIa on coagulation of plasma and whole blood J. Thromb. Haemostasis 12, 1678-1686
-
(2014)
J. Thromb. Haemostasis
, vol.12
, pp. 1678-1686
-
-
Hansson, K.M.1
Nielsen, S.2
Elg, M.3
Deinum, J.4
-
4
-
-
77950899732
-
Factor XIIa inhibitor recombinant human albumin Infestin-4 abolishes occlusive arterial thrombus formation without affecting bleeding
-
Hagedorn, I., Schmidbauer, S., Pleines, I., Kleinschnitz, C., Kronthaler, U., Stoll, G., Dickneite, G., and Nieswandt, B. (2010) Factor XIIa inhibitor recombinant human albumin Infestin-4 abolishes occlusive arterial thrombus formation without affecting bleeding Circulation 121, 1510-1517
-
(2010)
Circulation
, vol.121
, pp. 1510-1517
-
-
Hagedorn, I.1
Schmidbauer, S.2
Pleines, I.3
Kleinschnitz, C.4
Kronthaler, U.5
Stoll, G.6
Dickneite, G.7
Nieswandt, B.8
-
5
-
-
33645066112
-
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis
-
Kleinschnitz, C., Stoll, G., Bendszus, M., Schuh, K., Pauer, H. U., Burfeind, P., Renne, C., Gailani, D., Nieswandt, B., and Renne, T. (2006) Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis J. Exp. Med. 203, 513-518
-
(2006)
J. Exp. Med.
, vol.203
, pp. 513-518
-
-
Kleinschnitz, C.1
Stoll, G.2
Bendszus, M.3
Schuh, K.4
Pauer, H.U.5
Burfeind, P.6
Renne, C.7
Gailani, D.8
Nieswandt, B.9
Renne, T.10
-
6
-
-
84893834884
-
A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk
-
Larsson, M., Rayzman, V., Nolte, M. W., Nickel, K. F., Bjorkqvist, J., Jamsa, A., Hardy, M. P., Fries, M., Schmidbauer, S., Hedenqvist, P., Broome, M., Pragst, I., Dickneite, G., Wilson, M. J., Nash, A. D., Panousis, C., and Renne, T. (2014) A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk Sci. Transl. Med. 6, 222ra217
-
(2014)
Sci. Transl. Med.
, vol.6
, pp. 222ra217
-
-
Larsson, M.1
Rayzman, V.2
Nolte, M.W.3
Nickel, K.F.4
Bjorkqvist, J.5
Jamsa, A.6
Hardy, M.P.7
Fries, M.8
Schmidbauer, S.9
Hedenqvist, P.10
Broome, M.11
Pragst, I.12
Dickneite, G.13
Wilson, M.J.14
Nash, A.D.15
Panousis, C.16
Renne, T.17
-
7
-
-
84897538637
-
Factor XII inhibition reduces thrombus formation in a primate thrombosis model
-
Matafonov, A., Leung, P. Y., Gailani, A. E., Grach, S. L., Puy, C., Cheng, Q., Sun, M. F., McCarty, O. J., Tucker, E. I., Kataoka, H., Renne, T., Morrissey, J. H., Gruber, A., and Gailani, D. (2014) Factor XII inhibition reduces thrombus formation in a primate thrombosis model Blood 123, 1739-1746
-
(2014)
Blood
, vol.123
, pp. 1739-1746
-
-
Matafonov, A.1
Leung, P.Y.2
Gailani, A.E.3
Grach, S.L.4
Puy, C.5
Cheng, Q.6
Sun, M.F.7
McCarty, O.J.8
Tucker, E.I.9
Kataoka, H.10
Renne, T.11
Morrissey, J.H.12
Gruber, A.13
Gailani, D.14
-
8
-
-
22944462705
-
Defective thrombus formation in mice lacking coagulation factor XII
-
Renne, T., Pozgajova, M., Gruner, S., Schuh, K., Pauer, H. U., Burfeind, P., Gailani, D., and Nieswandt, B. (2005) Defective thrombus formation in mice lacking coagulation factor XII J. Exp. Med. 202, 271-281
-
(2005)
J. Exp. Med.
, vol.202
, pp. 271-281
-
-
Renne, T.1
Pozgajova, M.2
Gruner, S.3
Schuh, K.4
Pauer, H.U.5
Burfeind, P.6
Gailani, D.7
Nieswandt, B.8
-
9
-
-
84880447362
-
Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer
-
Woodruff, R. S., Xu, Y., Layzer, J., Wu, W., Ogletree, M. L., and Sullenger, B. A. (2013) Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer J. Thromb. Haemostasis 11, 1364-1373
-
(2013)
J. Thromb. Haemostasis
, vol.11
, pp. 1364-1373
-
-
Woodruff, R.S.1
Xu, Y.2
Layzer, J.3
Wu, W.4
Ogletree, M.L.5
Sullenger, B.A.6
-
10
-
-
84893856544
-
Factor XIIa inhibition by Infestin-4: In vitro mode of action and in vivo antithrombotic benefit
-
Xu, Y., Cai, T. Q., Castriota, G., Zhou, Y., Hoos, L., Jochnowitz, N., Loewrigkeit, C., Cook, J. A., Wickham, A., Metzger, J. M., Ogletree, M. L., Seiffert, D. A., and Chen, Z. (2014) Factor XIIa inhibition by Infestin-4: in vitro mode of action and in vivo antithrombotic benefit Thromb. Haemostasis 111, 694-704
-
(2014)
Thromb. Haemostasis
, vol.111
, pp. 694-704
-
-
Xu, Y.1
Cai, T.Q.2
Castriota, G.3
Zhou, Y.4
Hoos, L.5
Jochnowitz, N.6
Loewrigkeit, C.7
Cook, J.A.8
Wickham, A.9
Metzger, J.M.10
Ogletree, M.L.11
Seiffert, D.A.12
Chen, Z.13
-
11
-
-
84869854718
-
In vivo roles of factor XII
-
Renne, T., Schmaier, A. H., Nickel, K. F., Blomback, M., and Maas, C. (2012) In vivo roles of factor XII Blood 120, 4296-4303
-
(2012)
Blood
, vol.120
, pp. 4296-4303
-
-
Renne, T.1
Schmaier, A.H.2
Nickel, K.F.3
Blomback, M.4
Maas, C.5
-
12
-
-
34250191847
-
Evidence of a U-shaped association between factor XII activity and overall survival
-
Endler, G., Marsik, C., Jilma, B., Schickbauer, T., Quehenberger, P., and Mannhalter, C. (2007) Evidence of a U-shaped association between factor XII activity and overall survival J. Thromb. Haemostasis 5, 1143-1148
-
(2007)
J. Thromb. Haemostasis
, vol.5
, pp. 1143-1148
-
-
Endler, G.1
Marsik, C.2
Jilma, B.3
Schickbauer, T.4
Quehenberger, P.5
Mannhalter, C.6
-
13
-
-
0030812723
-
Mutations in the human factor XII gene
-
Schloesser, M., Zeerleder, S., Lutze, G., Halbmayer, W. M., Hofferbert, S., Hinney, B., Koestering, H., Lammle, B., Pindur, G., Thies, K., Kohler, M., and Engel, W. (1997) Mutations in the human factor XII gene Blood 90, 3967-3977
-
(1997)
Blood
, vol.90
, pp. 3967-3977
-
-
Schloesser, M.1
Zeerleder, S.2
Lutze, G.3
Halbmayer, W.M.4
Hofferbert, S.5
Hinney, B.6
Koestering, H.7
Lammle, B.8
Pindur, G.9
Thies, K.10
Kohler, M.11
Engel, W.12
-
14
-
-
0028054973
-
The prevalence of moderate and severe FXII (Hageman factor) deficiency among the normal population: Evaluation of the incidence of FXII deficiency among 300 healthy blood donors
-
Halbmayer, W. M., Haushofer, A., Schon, R., Mannhalter, C., Strohmer, E., Baumgarten, K., and Fischer, M. (1994) The prevalence of moderate and severe FXII (Hageman factor) deficiency among the normal population: evaluation of the incidence of FXII deficiency among 300 healthy blood donors Thromb. Haemostasis 71, 68-72
-
(1994)
Thromb. Haemostasis
, vol.71
, pp. 68-72
-
-
Halbmayer, W.M.1
Haushofer, A.2
Schon, R.3
Mannhalter, C.4
Strohmer, E.5
Baumgarten, K.6
Fischer, M.7
-
15
-
-
0036712320
-
Infestin, a thrombin inhibitor presents in Triatoma infestans midgut, a Chagas disease vector: Gene cloning, expression and characterization of the inhibitor
-
Campos, I. T., Amino, R., Sampaio, C. A., Auerswald, E. A., Friedrich, T., Lemaire, H. G., Schenkman, S., and Tanaka, A. S. (2002) Infestin, a thrombin inhibitor presents in Triatoma infestans midgut, a Chagas disease vector: gene cloning, expression and characterization of the inhibitor Insect Biochem. Mol. Biol. 32, 991-997
-
(2002)
Insect Biochem. Mol. Biol.
, vol.32
, pp. 991-997
-
-
Campos, I.T.1
Amino, R.2
Sampaio, C.A.3
Auerswald, E.A.4
Friedrich, T.5
Lemaire, H.G.6
Schenkman, S.7
Tanaka, A.S.8
-
16
-
-
8844236924
-
Identification and characterization of a novel factor XIIa inhibitor in the hematophagous insect, Triatoma infestans (Hemiptera: Reduviidae)
-
Campos, I. T., Tanaka-Azevedo, A. M., and Tanaka, A. S. (2004) Identification and characterization of a novel factor XIIa inhibitor in the hematophagous insect, Triatoma infestans (Hemiptera: Reduviidae) FEBS Lett. 577, 512-516
-
(2004)
FEBS Lett.
, vol.577
, pp. 512-516
-
-
Campos, I.T.1
Tanaka-Azevedo, A.M.2
Tanaka, A.S.3
-
17
-
-
44949161937
-
Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors
-
Robert, S., Bertolla, C., Masereel, B., Dogne, J. M., and Pochet, L. (2008) Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors J. Med. Chem. 51, 3077-3080
-
(2008)
J. Med. Chem.
, vol.51
, pp. 3077-3080
-
-
Robert, S.1
Bertolla, C.2
Masereel, B.3
Dogne, J.M.4
Pochet, L.5
-
18
-
-
49649106518
-
Highly potent and selective substrate analogue factor Xa inhibitors containing D-homophenylalanine analogues as P3 residue: Part 2
-
Sturzebecher, A., Donnecke, D., Schweinitz, A., Schuster, O., Steinmetzer, P., Sturzebecher, U., Kotthaus, J., Clement, B., Sturzebecher, J., and Steinmetzer, T. (2007) Highly potent and selective substrate analogue factor Xa inhibitors containing D-homophenylalanine analogues as P3 residue: part 2 ChemMedChem. 2, 1043-1053
-
(2007)
ChemMedChem.
, vol.2
, pp. 1043-1053
-
-
Sturzebecher, A.1
Donnecke, D.2
Schweinitz, A.3
Schuster, O.4
Steinmetzer, P.5
Sturzebecher, U.6
Kotthaus, J.7
Clement, B.8
Sturzebecher, J.9
Steinmetzer, T.10
-
19
-
-
84877713656
-
Development of a selective peptide macrocycle inhibitor of coagulation factor XII toward the generation of a safe antithrombotic therapy
-
Baeriswyl, V., Calzavarini, S., Gerschheimer, C., Diderich, P., Angelillo-Scherrer, A., and Heinis, C. (2013) Development of a selective peptide macrocycle inhibitor of coagulation factor XII toward the generation of a safe antithrombotic therapy J. Med. Chem. 56, 3742-3746
-
(2013)
J. Med. Chem.
, vol.56
, pp. 3742-3746
-
-
Baeriswyl, V.1
Calzavarini, S.2
Gerschheimer, C.3
Diderich, P.4
Angelillo-Scherrer, A.5
Heinis, C.6
-
20
-
-
84893436241
-
Peptide ligands stabilized by small molecules
-
Chen, S., Bertoldo, D., Angelini, A., Pojer, F., and Heinis, C. (2014) Peptide ligands stabilized by small molecules Angew. Chem. 53, 1602-1606
-
(2014)
Angew. Chem.
, vol.53
, pp. 1602-1606
-
-
Chen, S.1
Bertoldo, D.2
Angelini, A.3
Pojer, F.4
Heinis, C.5
-
21
-
-
84860259724
-
Structurally diverse cyclisation linkers impose different backbone conformations in bicyclic peptides
-
Chen, S., Morales-Sanfrutos, J., Angelini, A., Cutting, B., and Heinis, C. (2012) Structurally diverse cyclisation linkers impose different backbone conformations in bicyclic peptides Chembiochem 13, 1032-1038
-
(2012)
Chembiochem
, vol.13
, pp. 1032-1038
-
-
Chen, S.1
Morales-Sanfrutos, J.2
Angelini, A.3
Cutting, B.4
Heinis, C.5
-
22
-
-
0019129293
-
Hageman factor fragment inhibitor in corn seeds: Purification and characterization
-
Hojima, Y., Pierce, J. V., and Pisano, J. J. (1980) Hageman factor fragment inhibitor in corn seeds: purification and characterization Thromb. Res. 20, 149-162
-
(1980)
Thromb. Res.
, vol.20
, pp. 149-162
-
-
Hojima, Y.1
Pierce, J.V.2
Pisano, J.J.3
-
23
-
-
67049119829
-
Monitoring thrombin generation: Is addition of corn trypsin inhibitor needed?
-
Spronk, H. M., Dielis, A. W., Panova-Noeva, M., van Oerle, R., Govers-Riemslag, J. W., Hamulyak, K., Falanga, A., and Cate, H. T. (2009) Monitoring thrombin generation: is addition of corn trypsin inhibitor needed? Thromb. Haemostasis 101, 1156-1162
-
(2009)
Thromb. Haemostasis
, vol.101
, pp. 1156-1162
-
-
Spronk, H.M.1
Dielis, A.W.2
Panova-Noeva, M.3
Van Oerle, R.4
Govers-Riemslag, J.W.5
Hamulyak, K.6
Falanga, A.7
Cate, H.T.8
-
24
-
-
0342445397
-
What can the structures of enzyme-inhibitor complexes tell us about the structures of enzyme substrate complexes?
-
Laskowski, M. and Qasim, M. A. (2000) What can the structures of enzyme-inhibitor complexes tell us about the structures of enzyme substrate complexes? Biochim. Biophys. Acta 1477, 324-337
-
(2000)
Biochim. Biophys. Acta
, vol.1477
, pp. 324-337
-
-
Laskowski, M.1
Qasim, M.A.2
-
25
-
-
41849145377
-
Corn trypsin inhibitor in fluorogenic thrombin-generation measurements is only necessary at low tissue factor concentrations and influences the relationship between factor VIII coagulant activity and thromblogram parameters
-
Van Veen, J. J., Gatt, A., Cooper, P. C., Kitchen, S., Bowyer, A. E., and Makris, M. (2008) Corn trypsin inhibitor in fluorogenic thrombin-generation measurements is only necessary at low tissue factor concentrations and influences the relationship between factor VIII coagulant activity and thromblogram parameters Blood Coagulation Fibrinolysis 19, 183-189
-
(2008)
Blood Coagulation Fibrinolysis
, vol.19
, pp. 183-189
-
-
Van Veen, J.J.1
Gatt, A.2
Cooper, P.C.3
Kitchen, S.4
Bowyer, A.E.5
Makris, M.6
-
26
-
-
84870242904
-
Thrombin generation assay: A new tool to predict and optimize clinical outcome in cardiovascular patients?
-
Campo, G., Pavasini, R., Pollina, A., Fileti, L., Marchesini, J., Tebaldi, M., and Ferrari, R. (2012) Thrombin generation assay: a new tool to predict and optimize clinical outcome in cardiovascular patients? Blood Coagulation Fibrinolysis 23, 680-687
-
(2012)
Blood Coagulation Fibrinolysis
, vol.23
, pp. 680-687
-
-
Campo, G.1
Pavasini, R.2
Pollina, A.3
Fileti, L.4
Marchesini, J.5
Tebaldi, M.6
Ferrari, R.7
-
27
-
-
84891893038
-
Recommendations for performing thromboelastography/thromboelastometry in hemophilia: Communication from the SSC of the ISTH
-
Chitlur, M., Rivard, G. E., Lillicrap, D., Mann, K., Shima, M., Young, G., and Haemostasi, I. S. T. (2014) Recommendations for performing thromboelastography/thromboelastometry in hemophilia: communication from the SSC of the ISTH J. Thromb. Haemostasis 12, 103-106
-
(2014)
J. Thromb. Haemostasis
, vol.12
, pp. 103-106
-
-
Chitlur, M.1
Rivard, G.E.2
Lillicrap, D.3
Mann, K.4
Shima, M.5
Young, G.6
Haemostasi, I.S.T.7
-
28
-
-
80055116539
-
Surface modification with polyethylene glycol-corn trypsin inhibitor conjugate to inhibit the contact factor pathway on blood-contacting surfaces
-
Alibeik, S., Zhu, S., Yau, J. W., Weitz, J. I., and Brash, J. L. (2011) Surface modification with polyethylene glycol-corn trypsin inhibitor conjugate to inhibit the contact factor pathway on blood-contacting surfaces Acta Biomater. 7, 4177-4186
-
(2011)
Acta Biomater.
, vol.7
, pp. 4177-4186
-
-
Alibeik, S.1
Zhu, S.2
Yau, J.W.3
Weitz, J.I.4
Brash, J.L.5
-
29
-
-
84873973841
-
Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo
-
Yau, J. W., Stafford, A. R., Liao, P., Fredenburgh, J. C., Roberts, R., Brash, J. L., and Weitz, J. I. (2012) Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo Acta Biomater. 8, 4092-4100
-
(2012)
Acta Biomater.
, vol.8
, pp. 4092-4100
-
-
Yau, J.W.1
Stafford, A.R.2
Liao, P.3
Fredenburgh, J.C.4
Roberts, R.5
Brash, J.L.6
Weitz, J.I.7
-
30
-
-
84870015800
-
Bicyclization and tethering to albumin yields long-acting peptide antagonists
-
Angelini, A., Morales-Sanfrutos, J., Diderich, P., Chen, S., and Heinis, C. (2012) Bicyclization and tethering to albumin yields long-acting peptide antagonists J. Med. Chem. 55, 10187-10197
-
(2012)
J. Med. Chem.
, vol.55
, pp. 10187-10197
-
-
Angelini, A.1
Morales-Sanfrutos, J.2
Diderich, P.3
Chen, S.4
Heinis, C.5
-
31
-
-
84877115203
-
Phage selection of bicyclic peptides
-
Rentero Rebollo, I. and Heinis, C. (2013) Phage selection of bicyclic peptides Methods 60, 46-54
-
(2013)
Methods
, vol.60
, pp. 46-54
-
-
Rentero Rebollo, I.1
Heinis, C.2
-
32
-
-
48849113878
-
Comparative protein structure modeling using MODELLER
-
Chapter 2, Unit 29, Wiley Interscience, Hoboken, NJ
-
Eswar, N., Webb, B., Marti-Renom, M. A., Madhusudhan, M. S., Eramian, D., Shen, M. Y., Pieper, U., and Sali, A. (2007) Comparative protein structure modeling using MODELLER, Current Protocols in Protein Science/Editorial Board, John E. Coligan···[et al.], Chapter 2, Unit 29, Wiley Interscience, Hoboken, NJ.
-
(2007)
Current Protocols in Protein Science/Editorial Board, John E. Coligan··· [Et Al.]
-
-
Eswar, N.1
Webb, B.2
Marti-Renom, M.A.3
Madhusudhan, M.S.4
Eramian, D.5
Shen, M.Y.6
Pieper, U.7
Sali, A.8
-
33
-
-
84873719639
-
An overview of the Amber biomolecular simulation package
-
Salomon-Ferrer, R., Case, D. A., and Walker, R. C. (2013) An overview of the Amber biomolecular simulation package Wires Comput. Mol. Sci. 3, 198-210
-
(2013)
Wires Comput. Mol. Sci.
, vol.3
, pp. 198-210
-
-
Salomon-Ferrer, R.1
Case, D.A.2
Walker, R.C.3
-
34
-
-
0242401773
-
Calibrated automated thrombin generation measurement in clotting plasma
-
Hemker, H. C., Giesen, P., Al Dieri, R., Regnault, V., de Smedt, E., Wagenvoord, R., Lecompte, T., and Beguin, S. (2003) Calibrated automated thrombin generation measurement in clotting plasma Pathophysiol. Haemostasis Thromb. 33, 4-15
-
(2003)
Pathophysiol. Haemostasis Thromb.
, vol.33
, pp. 4-15
-
-
Hemker, H.C.1
Giesen, P.2
Al Dieri, R.3
Regnault, V.4
De Smedt, E.5
Wagenvoord, R.6
Lecompte, T.7
Beguin, S.8
|