Development of a selective peptide macrocycle inhibitor of coagulation factor XII toward the generation of a safe antithrombotic therapy

Journal of Medicinal Chemistry

Volumn 56, Issue 9, 2013, Pages 3742-3746

  Baeriswyl, Vanessa ^a   Calzavarini, Sara ^b   Gerschheimer, Christiane ^b   Diderich, Philippe ^a   Angelillo Scherrer, Anne ^b   Heinis, Christian ^a  

^a EPFL   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 12; PROTEIN INHIBITOR;

ANTICOAGULANT THERAPY; ARTICLE; PHAGE DISPLAY;

AMINO ACID SEQUENCE; DRUG DISCOVERY; DRUG SYNERGISM; FACTOR XII; FIBRINOLYTIC AGENTS; HUMANS; PEPTIDES, CYCLIC; PLASMA KALLIKREIN; SAFETY;

EID: 84877713656     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm400236j     Document Type: Article

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