PH-sensitive polymer-liposome-based antigen delivery systems potentiated with interferon-γ gene lipoplex for efficient cancer immunotherapy

Biomaterials

Volumn 67, Issue , 2015, Pages 214-224

  Yuba, Eiji ^a   Kanda, Yuhei ^a   Yoshizaki, Yuta ^a   Teranishi, Ryoma ^a   Harada, Atsushi ^a   Sugiura, Kikuya ^a   Izawa, Takeshi ^a   Yamate, Jyoji ^a   Sakaguchi, Naoki ^b   Koiwai, Kazunori ^b   Kono, Kenji ^a  

^a Osaka Prefecture University   (Japan)

^b TERUMO CORPORATION   (Japan)

Author keywords

Cancer immunotherapy; Cellular immunity; Dendritic cell; Interferon ; Lipoplex; PH sensitive liposome

Indexed keywords

ANTIBIOTICS; ANTIGENS; CELL CULTURE; COMPLEXATION; DISEASES; ENCODING (SYMBOLS); GENES; GLYCOPROTEINS; MAMMALS; PH SENSORS; PROTEINS; SIGNAL ENCODING; TUMORS;

CANCER IMMUNOTHERAPY; CELLULAR IMMUNITY; DENDRITIC CELLS; LIPOPLEXES; PH-SENSITIVE LIPOSOMES;

LIPOSOMES;

GAMMA INTERFERON; LIPOPLEX; LIPOSOME; OVALBUMIN; PLASMID DNA; ANTIGEN; POLYGLYCIDOL; POLYMER; PROPANEDIOL DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CANCER TISSUE; CELLULAR IMMUNITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSOL; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; ENDOCYTOSIS; ENDOSOME; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; HISTOPATHOLOGY; IMMUNE RESPONSE; LIPOSOMAL GENE DELIVERY SYSTEM; LYSOSOME; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; SPLEEN CELL; STATIC ELECTRICITY; THERAPY EFFECT; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL INOCULATION; TUMOR VOLUME; ZETA POTENTIAL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHEMISTRY; CONFOCAL MICROSCOPY; DENDRITE; DRUG DELIVERY SYSTEM; ELECTROPHORESIS; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; IMMUNOLOGY; IMMUNOTHERAPY; METABOLISM; NEOPLASMS; PARTICLE SIZE; PATHOLOGY; SPLEEN; SUBCUTANEOUS TISSUE; TUMOR CELL LINE;

MURINAE; MUS;

ANIMALS; ANTIGENS; CELL LINE, TUMOR; DENDRITES; DRUG DELIVERY SYSTEMS; ELECTROPHORESIS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HYDROGEN-ION CONCENTRATION; IMMUNOTHERAPY; INTERFERON-GAMMA; LIPOSOMES; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; NEOPLASMS; OVALBUMIN; PARTICLE SIZE; POLYMERS; PROPYLENE GLYCOLS; SPLEEN; STATIC ELECTRICITY; SUBCUTANEOUS TISSUE; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84939640567     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.07.031     Document Type: Article

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