Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Zarrouk, Marouan ^a   Finlay, David K ^b   Foretz, Marc ^c,d,e   Viollet, Benoit ^c,d,e   Cantrell, Doreen A ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c INSERM   (France)

^d CNRS   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD69 ANTIGEN; CD98 ANTIGEN; GLUCOSE TRANSPORTER 1; HERMES ANTIGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 2 RECEPTOR ALPHA; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; METFORMIN; MYC PROTEIN; PROTEIN S6; S6 KINASE; T LYMPHOCYTE RECEPTOR; GLUCOSE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

AEROBIC GLYCOLYSIS; AEROBIC METABOLISM; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CD8+ T LYMPHOCYTE; CELL FUNCTION; CELL GROWTH; CELL METABOLISM; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DRUG SENSITIVITY; EFFECTOR CELL; ENZYME INHIBITION; GLUCOSE TRANSPORT; IMMUNOREGULATION; LYMPHOBLAST; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; OXIDATIVE PHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANIMAL; CELL LINE; DRUG EFFECTS; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BIOLOGICAL TRANSPORT; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; GLUCOSE; METFORMIN; MICE; MULTIPROTEIN COMPLEXES; T-LYMPHOCYTES; TOR SERINE-THREONINE KINASES;

EID: 84939612531     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106710     Document Type: Article

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