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Volumn 8, Issue 3, 2013, Pages

LKB1 Mediates the Development of Conventional and Innate T Cells via AMP-Dependent Kinase Autonomous Pathways

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE MONOPHOSPHATE ACTIVATED PROTEIN KINASE ALPHA 1; CD69 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; GAMMA INTERFERON; PROTEIN KINASE; PROTEIN KINASE LKB1; STROMAL CELL DERIVED FACTOR 1; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

EID: 84875336822     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060217     Document Type: Article
Times cited : (18)

References (21)
  • 1
    • 77954901331 scopus 로고    scopus 로고
    • Decision checkpoints in the thymus
    • doi: 10.1038/ni.1887
    • Carpenter AC, Bosselut R, (2010) Decision checkpoints in the thymus. Nature Immunology 11: 666-673 doi:10.1038/ni.1887.
    • (2010) Nature Immunology , vol.11 , pp. 666-673
    • Carpenter, A.C.1    Bosselut, R.2
  • 2
    • 84859159573 scopus 로고    scopus 로고
    • CD4-CD8 differentiation in the thymus: connecting circuits and building memories
    • doi: 10.1016/j.coi.2012.02.002
    • Xiong Y, Bosselut R, (2012) CD4-CD8 differentiation in the thymus: connecting circuits and building memories. Current Opinion in Immunology 24: 139-145 doi:10.1016/j.coi.2012.02.002.
    • (2012) Current Opinion in Immunology , vol.24 , pp. 139-145
    • Xiong, Y.1    Bosselut, R.2
  • 4
    • 33749526537 scopus 로고    scopus 로고
    • Identification of Pre- and Postselection TCRαβ+ Intraepithelial Lymphocyte Precursors in the Thymus
    • doi: 10.1016/j.immuni.2006.08.018
    • Gangadharan D, Lambolez F, Attinger A, Wang-Zhu Y, Sullivan BA, et al. (2006) Identification of Pre- and Postselection TCRαβ+ Intraepithelial Lymphocyte Precursors in the Thymus. Immunity 25: 631-641 doi:10.1016/j.immuni.2006.08.018.
    • (2006) Immunity , vol.25 , pp. 631-641
    • Gangadharan, D.1    Lambolez, F.2    Attinger, A.3    Wang-Zhu, Y.4    Sullivan, B.A.5
  • 5
    • 79959664629 scopus 로고    scopus 로고
    • The light and dark sides of intestinal intraepithelial lymphocytes
    • doi: 10.1038/nri3007
    • Cheroutre H, Lambolez F, Mucida D, (2011) The light and dark sides of intestinal intraepithelial lymphocytes. Nature Reviews Immunology 11: 445-456 doi:10.1038/nri3007.
    • (2011) Nature Reviews Immunology , vol.11 , pp. 445-456
    • Cheroutre, H.1    Lambolez, F.2    Mucida, D.3
  • 6
    • 74249122511 scopus 로고    scopus 로고
    • LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells
    • doi: 10.1002/eji.200939677
    • Tamas P, Macintyre A, Finlay D, Clarke R, Feijoo Carnero C, et al. (2009) LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells. Eur J Immunol 40: 242-253 doi:10.1002/eji.200939677.
    • (2009) Eur J Immunol , vol.40 , pp. 242-253
    • Tamas, P.1    Macintyre, A.2    Finlay, D.3    Clarke, R.4    Feijoo Carnero, C.5
  • 7
    • 73849112608 scopus 로고    scopus 로고
    • The serine/threonine kinase LKB1 controls thymocyte survival through regulation of AMPK activation and Bcl-XL expression
    • doi: 10.1038/cr.2009.141
    • Cao Y, Li H, Liu H, Zheng C, Ji H, et al. (2009) The serine/threonine kinase LKB1 controls thymocyte survival through regulation of AMPK activation and Bcl-XL expression. Cell Research pp. 99-108 doi:10.1038/cr.2009.141.
    • (2009) Cell Research , pp. 99-108
    • Cao, Y.1    Li, H.2    Liu, H.3    Zheng, C.4    Ji, H.5
  • 8
    • 80054726323 scopus 로고    scopus 로고
    • The Liver Kinase B1 Is a Central Regulator of T Cell Development, Activation, and Metabolism
    • doi: 10.4049/jimmunol.1100367
    • MacIver NJ, Blagih J, Saucillo DC, Tonelli L, Griss T, et al. (2011) The Liver Kinase B1 Is a Central Regulator of T Cell Development, Activation, and Metabolism. The Journal of Immunology 187: 4187-4198 doi:10.4049/jimmunol.1100367.
    • (2011) The Journal of Immunology , vol.187 , pp. 4187-4198
    • MacIver, N.J.1    Blagih, J.2    Saucillo, D.C.3    Tonelli, L.4    Griss, T.5
  • 9
    • 79956132815 scopus 로고    scopus 로고
    • LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
    • doi: 10.1038/emboj.2011.116
    • Cao Y, Li H, Liu H, Zhang M, Hua Z, et al. (2011) LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection. The EMBO Journal pp. 1-11 doi:10.1038/emboj.2011.116.
    • (2011) The EMBO Journal , pp. 1-11
    • Cao, Y.1    Li, H.2    Liu, H.3    Zhang, M.4    Hua, Z.5
  • 10
    • 84858782079 scopus 로고    scopus 로고
    • AMPK: a nutrient and energy sensor that maintains energy homeostasis
    • doi: 10.1038/nrm3311
    • Hardie DG, Ross FA, Hawley SA, (2012) AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nature Publishing Group 13: 251-262 doi:10.1038/nrm3311.
    • (2012) Nature Publishing Group , vol.13 , pp. 251-262
    • Hardie, D.G.1    Ross, F.A.2    Hawley, S.A.3
  • 11
    • 44849141880 scopus 로고    scopus 로고
    • AMP-activated protein kinase regulates lymphocyte responses to metabolic stress but is largely dispensable for immune cell development and function
    • doi: 10.1002/eji.200738045
    • Mayer A, Denanglaire S, Viollet B, Leo O, Andris F, (2008) AMP-activated protein kinase regulates lymphocyte responses to metabolic stress but is largely dispensable for immune cell development and function. Eur J Immunol 38: 948-956 doi:10.1002/eji.200738045.
    • (2008) Eur J Immunol , vol.38 , pp. 948-956
    • Mayer, A.1    Denanglaire, S.2    Viollet, B.3    Leo, O.4    Andris, F.5
  • 12
    • 79959646651 scopus 로고    scopus 로고
    • Signal integration and crosstalk during thymocyte migration and emigration
    • doi: 10.1038/nri2989
    • Love PE, Bhandoola A, (2011) Signal integration and crosstalk during thymocyte migration and emigration. Nature Reviews Immunology 11: 469-477 doi:10.1038/nri2989.
    • (2011) Nature Reviews Immunology , vol.11 , pp. 469-477
    • Love, P.E.1    Bhandoola, A.2
  • 13
    • 67651166585 scopus 로고    scopus 로고
    • Themis, a T cell-specific protein important for late thymocyte development
    • doi: 10.1038/ni.1768
    • Lesourne R, Uehara S, Lee J, Song K-D, Li L, et al. (2009) Themis, a T cell-specific protein important for late thymocyte development. Nature Immunology 10: 840-847 doi:10.1038/ni.1768.
    • (2009) Nature Immunology , vol.10 , pp. 840-847
    • Lesourne, R.1    Uehara, S.2    Lee, J.3    Song, K.-D.4    Li, L.5
  • 14
    • 78650645408 scopus 로고    scopus 로고
    • Temporal Differences in the Dependency on Phosphoinositide-Dependent Kinase 1 Distinguish the Development of Invariant V 14 NKT Cells and Conventional T Cells
    • Available:
    • Finlay DK, Kelly AP, Clarke R, Sinclair LV, Deak M, et al. (2010) Temporal Differences in the Dependency on Phosphoinositide-Dependent Kinase 1 Distinguish the Development of Invariant V 14 NKT Cells and Conventional T Cells. 185: 5973-5982 Available:http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1000827.
    • (2010) , vol.185 , pp. 5973-5982
    • Finlay, D.K.1    Kelly, A.P.2    Clarke, R.3    Sinclair, L.V.4    Deak, M.5
  • 15
    • 77953939928 scopus 로고    scopus 로고
    • c-Myc controls the development of CD8 TCR intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15-dependent survival
    • doi: 10.1182/blood-2009-11-254698
    • Jiang W, Ferrero I, Laurenti E, Trumpp A, MacDonald HR, (2010) c-Myc controls the development of CD8 TCR intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15-dependent survival. Blood 115: 4431-4438 doi:10.1182/blood-2009-11-254698.
    • (2010) Blood , vol.115 , pp. 4431-4438
    • Jiang, W.1    Ferrero, I.2    Laurenti, E.3    Trumpp, A.4    MacDonald, H.R.5
  • 16
    • 66649128115 scopus 로고    scopus 로고
    • Intrathymic proliferation wave essential for Valpha14+ natural killer T cell development depends on c-Myc
    • doi: 10.1073/pnas.0812255106
    • Dose M, Sleckman BP, Han J, Bredemeyer AL, Bendelac A, et al. (2009) Intrathymic proliferation wave essential for Valpha14+ natural killer T cell development depends on c-Myc. Proc Natl Acad Sci USA 106: 8641-8646 doi:10.1073/pnas.0812255106.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8641-8646
    • Dose, M.1    Sleckman, B.P.2    Han, J.3    Bredemeyer, A.L.4    Bendelac, A.5
  • 17
    • 0028863870 scopus 로고
    • Positive selection of thymocytes involves sustained interactions with the thymic microenvironment
    • Wilkinson RW, Anderson G, Owen JJ, Jenkinson EJ, (1995) Positive selection of thymocytes involves sustained interactions with the thymic microenvironment. J Immunol 155: 5234-5240.
    • (1995) J Immunol , vol.155 , pp. 5234-5240
    • Wilkinson, R.W.1    Anderson, G.2    Owen, J.J.3    Jenkinson, E.J.4
  • 18
    • 12144287284 scopus 로고    scopus 로고
    • LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
    • doi: 10.1038/sj.emboj.7600110
    • Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, et al. (2004) LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. The EMBO Journal 23: 833-843 doi:10.1038/sj.emboj.7600110.
    • (2004) The EMBO Journal , vol.23 , pp. 833-843
    • Lizcano, J.M.1    Göransson, O.2    Toth, R.3    Deak, M.4    Morrice, N.A.5
  • 19
    • 77953653569 scopus 로고    scopus 로고
    • New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion
    • doi: 10.1126/scisignal.2000616
    • Zagorska A, Deak M, Campbell DG, Banerjee S, Hirano M, et al. (2010) New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion. Science Signaling 3: ra25-ra25 doi:10.1126/scisignal.2000616.
    • (2010) Science Signaling , vol.3
    • Zagorska, A.1    Deak, M.2    Campbell, D.G.3    Banerjee, S.4    Hirano, M.5
  • 20
    • 84859167179 scopus 로고    scopus 로고
    • Deregulated MYC expression induces dependence upon AMPK-related kinase 5
    • doi: 10.1038/nature10927
    • Liu L, Ulbrich J, Müller J, Wüstefeld T, Aeberhard L, et al. (2013) Deregulated MYC expression induces dependence upon AMPK-related kinase 5. Nature 483: 608-612 doi:10.1038/nature10927.
    • (2013) Nature , vol.483 , pp. 608-612
    • Liu, L.1    Ulbrich, J.2    Müller, J.3    Wüstefeld, T.4    Aeberhard, L.5
  • 21
    • 20044370885 scopus 로고    scopus 로고
    • Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
    • Available:
    • Sakamoto K, McCarthy A, Smith D, Green KA, Grahame Hardie D, et al. (2005) Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction. The EMBO Journal 24: 1810-1820 Available:http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=15889149&retmode=ref&cmd=prlinks.
    • (2005) The EMBO Journal , vol.24 , pp. 1810-1820
    • Sakamoto, K.1    McCarthy, A.2    Smith, D.3    Green, K.A.4    Grahame Hardie, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.