Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy

Acta Neuropathologica

Volumn 130, Issue 3, 2015, Pages 373-387

  Simon, Christian M ^a,e   Rauskolb, Stefanie ^a   Gunnersen, Jennifer M ^a,f   Holtmann, Bettina ^a,g   Drepper, Carsten ^a,h   Dombert, Benjamin ^a   Braga, Massimiliano ^a,b,c   Wiese, Stefan ^a,i   Jablonka, Sibylle ^a   Pühringer, Dirk ^a   Zielasek, Jürgen ^a,j   Hoeflich, Andreas ^d,k   Silani, Vincenzo ^c,l   Wolf, Eckhard ^d   Kneitz, Susanne ^a   Sommer, Claudia ^a   Toyka, Klaus V ^a   Sendtner, Michael ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b AO Desio e Vimercate   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d UNIVERSITY OF MUNICH   (Germany)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f UNIVERSITY OF MELBOURNE   (Australia)

^g UNIVERSITY OF HOHENHEIM   (Germany)

^h UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

ⁱ RUHR UNIVERSITY BOCHUM   (Germany)

^j Leibniz Institute for Farm Animal Biology ^*  (Germany)

^k LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

^l ISTITUTO AUXOLOGICO ITALIANO   (Italy)

more..

Author keywords

Axonal degeneration; Diabetic polyneuropathy; Motor nerve biopsy; Neuropathy; Neurotrophic factors

Indexed keywords

ACTIN; PROTEIN KINASE B; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; CARRIER PROTEIN; IGFBP5-INTERACTING PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEUROPATHY; HUMAN; HUMAN TISSUE; MOTONEURON; MOTOR NERVE; MOUSE; NERVE FIBER DEGENERATION; NERVE FIBER GROWTH; NEUROFILAMENT; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORY NERVE; SPINAL GANGLION; TRANSGENIC MOUSE; UPREGULATION; ANIMAL; AXON; CELL CULTURE; CELL ENLARGEMENT; CELL SURVIVAL; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; MOTOR ACTIVITY; NERVE DEGENERATION; PATHOLOGY; PATHOPHYSIOLOGY; PHRENIC NERVE; PHYSIOLOGY; SCIATIC NERVE; SENSATION;

ANIMALS; AXONS; CARRIER PROTEINS; CELL ENLARGEMENT; CELL SURVIVAL; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; HUMANS; MICE, TRANSGENIC; MOTOR ACTIVITY; MOTOR NEURONS; NERVE DEGENERATION; PHRENIC NERVE; RECEPTOR, IGF TYPE 1; SCIATIC NERVE; SENSATION;

EID: 84939575526     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-015-1446-8     Document Type: Article

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