Differential interaction of hGDH1 and hGDH2 with manganese: Implications for metabolism and toxicity

Neurochemistry International

Volumn 88, Issue , 2015, Pages 60-65

  Dimovasili, Christina ^a   Aschner, Michael ^b   Plaitakis, Andreas ^a   Zaganas, Ioannis ^a  

^a UNIVERSITY OF CRETE   (Greece)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

ADP; Glutamate dehydrogenase; hGDH1; hGDH2; Manganese; Mitochondria

Indexed keywords

ADENOSINE DIPHOSPHATE; CALCIUM; DIVALENT CATION; GLUTAMATE DEHYDROGENASE; GLUTAMATE DEHYDROGENASE 1; GLUTAMATE DEHYDROGENASE 2; ISOENZYME; MAGNESIUM; MANGANESE; MITOCHONDRIAL ENZYME; UNCLASSIFIED DRUG; ENZYME INHIBITOR; GLUD1 PROTEIN, HUMAN; GLUD2 PROTEIN, HUMAN; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; CHEMICAL INTERACTION; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME INHIBITION; HILL COEFFICIENT; HUMAN; IC50; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL RESPIRATION; NEUROTOXICITY; NEUROTRANSMISSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; TOXICITY TESTING; ANIMAL; ANTAGONISTS AND INHIBITORS; DOSE RESPONSE; METABOLISM; PHYSIOLOGY; SPODOPTERA;

MAMMALIA;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUTAMATE DEHYDROGENASE; HUMANS; MANGANESE; PROTEIN BINDING; SPODOPTERA;

EID: 84939574170     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2015.03.004     Document Type: Article

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