An analysis of the effects of Mn2+ on oxidative phosphorylation in liver, brain, and heart mitochondria using state 3 oxidation rate assays

Toxicology and Applied Pharmacology

Volumn 249, Issue 1, 2010, Pages 65-75

  Gunter, Thomas E ^a   Gerstner, Brent ^a   Lester, Tobias ^a   Wojtovich, Andrew P ^a   Malecki, Jon ^a   Swarts, Steven G ^a   Brookes, Paul S ^a   Gavin, Claire E ^b   Gunter, Karlene K ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b NONE

Author keywords

Inhibition of Ca2+ activation; Mitochondrial differences; Mn toxicity; Oxidative phosphorylation; TCA cycle

Indexed keywords

ADENOSINE TRIPHOSPHATE; FUMARATE HYDRATASE; GLUTAMIC ACID; MALIC ACID; MANGANESE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SUCCINIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN MITOCHONDRION; CITRIC ACID CYCLE; CONTROLLED STUDY; FEMALE; HEART MITOCHONDRION; LIVER MITOCHONDRION; METABOLIC INHIBITION; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATION; OXIDATIVE PHOSPHORYLATION; RAT; ANIMAL; BIOSYNTHESIS; BRAIN; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; OXIDATION REDUCTION REACTION; SPRAGUE DAWLEY RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; BRAIN; FEMALE; MANGANESE; MITOCHONDRIA, HEART; MITOCHONDRIA, LIVER; OXIDATION-REDUCTION; OXIDATIVE PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77957888842     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.08.018     Document Type: Article

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