Salidroside improves endothelial function and alleviates atherosclerosis by activating a mitochondria-related AMPK/PI3K/Akt/eNOS pathway

Vascular Pharmacology

Volumn 72, Issue , 2015, Pages 141-152

  Xing, Sha Sha ^a,b   Yang, Xiao Yan ^a,b   Zheng, Tao ^a,b   Li, Wen Jing ^a,b   Wu, Dan ^a,b   Chi, Jiang Yang ^a,b   Bian, Fang ^a,b   Bai, Xiang Li ^a,b   Wu, Guang Jie ^a,b   Zhang, You Zhi ^a,b   Zhang, Cun Tai ^a,b   Zhang, Yong Hui ^a,b   Li, Yong Sheng ^a,b   Jin, Si ^a,b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Key Laboratory for Drug Target Researches and Pharmacodynamic Evaluation of Hubei Province   (China)

Author keywords

Atherosclerosis; Endothelial dysfunction; Mitochondria; Salidroside

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENYLATE KINASE; CARDIOVASCULAR AGENT; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SALIDROSIDE; TRIACYLGLYCEROL; ADENOSINE TRIPHOSPHATE; GLUCOSIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; NITRIC OXIDE; PHENOL DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIATHEROGENIC EFFECT; AORTA DISEASE; AORTA SINUS; AORTIC SINUS LESION; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SYNTHESIS; EXPERIMENTAL ATHEROSCLEROSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID DIET; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RANDOMIZATION; RAT; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; ATHEROSCLEROSIS; DRUG EFFECTS; ENDOTHELIUM CELL; METABOLISM; MITOCHONDRION; PHOSPHORYLATION; WISTAR RAT;

ADENOSINE TRIPHOSPHATE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ATHEROSCLEROSIS; DIET, HIGH-FAT; ENDOTHELIAL CELLS; GLUCOSIDES; MALE; MICE; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHENOLS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 84939566421     PISSN: 15371891     EISSN: 18793649     Source Type: Journal    
DOI: 10.1016/j.vph.2015.07.004     Document Type: Article

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