Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNγ/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis

Journal of Neuroimmune Pharmacology

Volumn 10, Issue 3, 2015, Pages 457-467

  Vilisaar, Janek ^a   Kawabe, Kiyokazu ^a   Braitch, Manjit ^a   Aram, Jehan ^a   Furtun, Yasemin ^a   Fahey, Angela J ^a   Chopra, Mark ^a   Tanasescu, Radu ^a,b   Tighe, Patrick J ^a   Gran, Bruno ^a   Pothoulakis, Charalabos ^c   Constantinescu, Cris S ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Human; IL 12; IL 23; Neurokinin 1 receptor; PBMC; Substance P; Tachykinins

Indexed keywords

CD3 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 23 P40; INTERLEUKIN 23P19; LUCIFERASE; MESSENGER RNA; NEUROKININ 1 RECEPTOR; SUBSTANCE P; UNCLASSIFIED DRUG;

ARTICLE; CD4+ T LYMPHOCYTE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INFLAMMATION; JURKAT CELL LINE; LUCIFERASE ASSAY; MULTIPLE SCLEROSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; UPREGULATION; CELL LINE; METABOLISM; MONONUCLEAR CELL; NORMAL HUMAN; T LYMPHOCYTE;

CELL LINE; HEALTHY VOLUNTEERS; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P35; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-17; INTERLEUKIN-23; INTERLEUKIN-23 SUBUNIT P19; LEUKOCYTES, MONONUCLEAR; RECEPTORS, NEUROKININ-1; SUBSTANCE P; T-LYMPHOCYTES;

EID: 84939563690     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-015-9589-x     Document Type: Article

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