메뉴 건너뛰기




Volumn 8, Issue 5, 2015, Pages 1118-1130

Deficiency of autophagy protein Map1-LC3b mediates IL-17-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; MAP1 LC3B PROTEIN; UNCLASSIFIED DRUG; IL17A PROTEIN, MOUSE; IL1B PROTEIN, MOUSE; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN;

EID: 84939560242     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2015.3     Document Type: Article
Times cited : (71)

References (50)
  • 1
    • 0344153462 scopus 로고    scopus 로고
    • Recent trends in severe respiratory syncytial virus (RSV) among US infants, 1997 to 2000
    • Leader, S. & Kohlhase, K. Recent trends in severe respiratory syncytial virus (RSV) among US infants, 1997 to 2000. J. Pediatr. 143, S127-S132 (2003).
    • (2003) J. Pediatr. , vol.143 , pp. S127-S132
    • Leader, S.1    Kohlhase, K.2
  • 2
    • 84855425514 scopus 로고    scopus 로고
    • Respiratory syncytial virus-associated hospitalizations among infants and young children in the United States, 1997-2006
    • Stockman, L.J., Curns, A.T., Anderson, L.J. & Fischer-Langley, G. Respiratory syncytial virus-associated hospitalizations among infants and young children in the United States, 1997-2006. Pediatr. Infect. Dis. J. 31, 5-9 (2012).
    • (2012) Pediatr. Infect. Dis. J. , vol.31 , pp. 5-9
    • Stockman, L.J.1    Curns, A.T.2    Anderson, L.J.3    Fischer-Langley, G.4
  • 3
    • 17644392071 scopus 로고    scopus 로고
    • Respiratory syncytial virus infection in elderly and high-risk adults
    • Falsey, A.R., Hennessey, P.A., Formica, M.A., Cox, C. & Walsh, E.E. Respiratory syncytial virus infection in elderly and high-risk adults. N. Engl. J. Med. 352, 1749-1759 (2005).
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1749-1759
    • Falsey, A.R.1    Hennessey, P.A.2    Formica, M.A.3    Cox, C.4    Walsh, E.E.5
  • 4
    • 13244268584 scopus 로고    scopus 로고
    • Viruses in asthma exacerbations
    • Tan, W.C. Viruses in asthma exacerbations. Curr. Opin. Pulm. Med. 11, 21-26 (2005).
    • (2005) Curr. Opin. Pulm. Med. , vol.11 , pp. 21-26
    • Tan, W.C.1
  • 5
    • 9644294626 scopus 로고    scopus 로고
    • Role of viruses in exacerbations of chronic obstructive pulmonary disease
    • Wedzicha, J.A. Role of viruses in exacerbations of chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 1, 115-120 (2004).
    • (2004) Proc. Am. Thorac. Soc. , vol.1 , pp. 115-120
    • Wedzicha, J.A.1
  • 6
    • 12144272208 scopus 로고    scopus 로고
    • Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13
    • Sigurs, N. et al. Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am. J. Respir. Crit. Care Med. 171, 137-141 (2005).
    • (2005) Am. J. Respir. Crit. Care Med. , vol.171 , pp. 137-141
    • Sigurs, N.1
  • 8
    • 33845709027 scopus 로고    scopus 로고
    • The histopathology of fatal untreated human respiratory syncytial virus infection
    • Johnson, J.E., Gonzales, R.A.,Olson, S.J., Wright,P.F. & Graham,B.S. The histopathology of fatal untreated human respiratory syncytial virus infection. Mod. Pathol. 20, 108-119 (2006).
    • (2006) Mod. Pathol. , vol.20 , pp. 108-119
    • Johnson, J.E.1    Gonzales, R.A.2    Olson, S.J.3    Wright, P.F.4    Graham, B.S.5
  • 9
    • 70349436096 scopus 로고    scopus 로고
    • Risk factors for respiratory failure associated with respiratory syncytial virus infection in adults
    • Duncan, C.B.,Walsh, E.E., Peterson,D.R., Lee, F. E.-H. & Falsey, A.R.Risk factors for respiratory failure associated with respiratory syncytial virus infection in adults. J. Infect. Dis. 200, 1242-1246 (2009).
    • (2009) J. Infect. Dis. , vol.200 , pp. 1242-1246
    • Duncan, C.B.1    Walsh, E.E.2    Peterson, D.R.3    Lee, F.E.-H.4    Falsey, A.R.5
  • 10
    • 80052508971 scopus 로고    scopus 로고
    • IL-17-induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease
    • Mukherjee, S. et al. IL-17-induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease. Am. J. Pathol. 179, 248-258 (2011).
    • (2011) Am. J. Pathol. , vol.179 , pp. 248-258
    • Mukherjee, S.1
  • 11
    • 84891743754 scopus 로고    scopus 로고
    • Novel inflammatory markers, clinical risk factors and virus type associated with severe respiratory syncytial virus infection
    • Tabarani, C.M. et al. Novel inflammatory markers, clinical risk factors and virus type associated with severe respiratory syncytial virus infection. Pediatr. Infect. Dis. J. 32, e437-e442 (2013).
    • (2013) Pediatr. Infect. Dis. J. , vol.32 , pp. e437-e442
    • Tabarani, C.M.1
  • 12
    • 80054741184 scopus 로고    scopus 로고
    • Th17 cytokines are critical for respiratory syncytial virusassociated airway hyperreponsiveness through regulation by complement C3a and tachykinins
    • Bera, M.M. et al. Th17 cytokines are critical for respiratory syncytial virusassociated airway hyperreponsiveness through regulation by complement C3a and tachykinins. J. Immunol. 187, 4245-4255 (2011).
    • (2011) J. Immunol. , vol.187 , pp. 4245-4255
    • Bera, M.M.1
  • 13
    • 81455135812 scopus 로고    scopus 로고
    • IL-17 boosts proinflammatory outcome of antiviral response in human cells
    • Ryzhakov, G. et al. IL-17 boosts proinflammatory outcome of antiviral response in human cells. J. Immunol. 187, 5357-5362 (2011).
    • (2011) J. Immunol. , vol.187 , pp. 5357-5362
    • Ryzhakov, G.1
  • 14
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E. et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441, 235-238 (2006).
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1
  • 15
    • 33646560950 scopus 로고    scopus 로고
    • Transforming growth factor-beta induces development of the T(H)17 lineage
    • Mangan, P.R. et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 441, 231-234 (2006).
    • (2006) Nature , vol.441 , pp. 231-234
    • Mangan, P.R.1
  • 16
    • 34548125305 scopus 로고    scopus 로고
    • Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
    • Acosta-Rodriguez, E.V., Napolitani, G., Lanzavecchia, A. & Sallusto, F. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat. Immunol. 8, 942-949 (2007).
    • (2007) Nat. Immunol. , vol.8 , pp. 942-949
    • Acosta-Rodriguez, E.V.1    Napolitani, G.2    Lanzavecchia, A.3    Sallusto, F.4
  • 17
    • 84355162720 scopus 로고    scopus 로고
    • Priming microenvironments dictate cytokine requirements for T helper 17 cell lineage commitment
    • Hu, W., Troutman, T.D., Edukulla, R. & Pasare, C. Priming microenvironments dictate cytokine requirements for T helper 17 cell lineage commitment. Immunity 35, 1010-1022 (2011).
    • (2011) Immunity , vol.35 , pp. 1010-1022
    • Hu, W.1    Troutman, T.D.2    Edukulla, R.3    Pasare, C.4
  • 18
    • 84867284676 scopus 로고    scopus 로고
    • Autophagy regulates IL-23 secretion and innate Tcell responses through effects on IL-1 secretion
    • de Castro, C.P. et al. Autophagy regulates IL-23 secretion and innate Tcell responses through effects on IL-1 secretion. J. Immunol. 189, 4144-4153 (2012).
    • (2012) J. Immunol. , vol.189 , pp. 4144-4153
    • De Castro, C.P.1
  • 19
    • 84878237993 scopus 로고    scopus 로고
    • Activation and regulation of the inflammasomes
    • Latz, E., Xiao, T.S. & Stutz, A. Activation and regulation of the inflammasomes. Nat. Rev. Immunol. 13, 397-411 (2013).
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 397-411
    • Latz, E.1    Xiao, T.S.2    Stutz, A.3
  • 20
    • 79953176280 scopus 로고    scopus 로고
    • Autophagy controls IL-1b secretion by targeting pro-IL-1b for degradation
    • Harris, J. et al. Autophagy controls IL-1b secretion by targeting pro-IL-1b for degradation. J. Biol. Chem. 286, 9587-9597 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 9587-9597
    • Harris, J.1
  • 21
    • 84857195479 scopus 로고    scopus 로고
    • Activation of autophagy by inflammatory signals limits IL-1b production by targeting ubiquitinated inflammasomes for destruction
    • Shi, C.-S. et al. Activation of autophagy by inflammatory signals limits IL-1b production by targeting ubiquitinated inflammasomes for destruction. Nat. Immunol. 13, 255-263 (2012).
    • (2012) Nat. Immunol. , vol.13 , pp. 255-263
    • Shi, C.-S.1
  • 22
    • 84871392549 scopus 로고    scopus 로고
    • Human respiratory syncytial virus viroporin SH: A viral recognition pathway used by the host to signal inflammasome activation
    • Triantafilou, K., Kar, S., Vakakis, E., Kotecha, S. & Triantafilou, M. Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation. Thorax 68, 66-75 (2013).
    • (2013) Thorax , vol.68 , pp. 66-75
    • Triantafilou, K.1    Kar, S.2    Vakakis, E.3    Kotecha, S.4    Triantafilou, M.5
  • 23
    • 84856249966 scopus 로고    scopus 로고
    • TLR2/MyD88/NF-kB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC Inflammasome during respiratory syncytial virus infection
    • Segovia, J. et al. TLR2/MyD88/NF-kB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC Inflammasome during respiratory syncytial virus infection. PLoS ONE 7, e29695 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e29695
    • Segovia, J.1
  • 24
    • 80054739227 scopus 로고    scopus 로고
    • Autophagy-mediated dendritic cell activation is essential for innate cytokine production and APC function with respiratory syncytial virus responses
    • Morris, S. et al. Autophagy-mediated dendritic cell activation is essential for innate cytokine production and APC function with respiratory syncytial virus responses. J. Immunol. 187, 3953-3961 (2011).
    • (2011) J. Immunol. , vol.187 , pp. 3953-3961
    • Morris, S.1
  • 25
    • 84883367287 scopus 로고    scopus 로고
    • Autophagy-inducing protein Beclin-1 in dendritic cells regulates CD4 T cell responses and disease severity during respiratory syncytial virus infection
    • Reed, M. et al. Autophagy-inducing protein Beclin-1 in dendritic cells regulates CD4 T cell responses and disease severity during respiratory syncytial virus infection. J. Immunol. 191, 2526-2537 (2013).
    • (2013) J. Immunol. , vol.191 , pp. 2526-2537
    • Reed, M.1
  • 26
    • 79951642032 scopus 로고    scopus 로고
    • Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
    • Nakahira, K. et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat. Immunol. 12, 222-230 (2011).
    • (2011) Nat. Immunol. , vol.12 , pp. 222-230
    • Nakahira, K.1
  • 27
    • 77956942677 scopus 로고    scopus 로고
    • Respiratory virus-induced TLR7 activation controls IL-17-associated increased mucus via IL-23 regulation
    • Lukacs, N.W. et al. Respiratory virus-induced TLR7 activation controls IL-17-associated increased mucus via IL-23 regulation. J. Immunol. 185, 2231-2239 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 2231-2239
    • Lukacs, N.W.1
  • 28
    • 84878191150 scopus 로고    scopus 로고
    • IRF4 transcription factor-dependent CD11b dendritic cells in human and mouse control mucosal IL-17 cytokine responses
    • Schlitzer, A. et al. IRF4 transcription factor-dependent CD11b dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity 38, 970-983 (2013).
    • (2013) Immunity , vol.38 , pp. 970-983
    • Schlitzer, A.1
  • 29
    • 84878167904 scopus 로고    scopus 로고
    • IRF4 transcription-factor-dependent CD103() CD11b() dendritic cells drive mucosal T helper 17 cell differentiation
    • Persson, E.K. et al. IRF4 transcription-factor-dependent CD103() CD11b() dendritic cells drive mucosal T helper 17 cell differentiation. Immunity 38, 958-969 (2013).
    • (2013) Immunity , vol.38 , pp. 958-969
    • Persson, E.K.1
  • 30
    • 78650434097 scopus 로고    scopus 로고
    • Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smokeinduced emphysema
    • Chen, Z.-H. et al. Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smokeinduced emphysema. Proc. Natl Acad. Sci. USA 107, 18880-18885 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 18880-18885
    • Chen, Z.-H.1
  • 31
    • 84859383698 scopus 로고    scopus 로고
    • Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death
    • Tanaka, A. et al. Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death. Am. J. Respir. Cell Mol. Biol. 46, 507-514 (2012).
    • (2012) Am. J. Respir. Cell Mol. Biol. , vol.46 , pp. 507-514
    • Tanaka, A.1
  • 32
    • 84896262503 scopus 로고    scopus 로고
    • The inositol requiring enzyme 1 inhibits respiratory syncytial virus replication
    • Hassan, I. et al. The inositol requiring enzyme 1 inhibits respiratory syncytial virus replication. J. Biol. Chem. 289, 7537-7546 (2014).
    • (2014) J. Biol. Chem. , vol.289 , pp. 7537-7546
    • Hassan, I.1
  • 33
    • 84856857478 scopus 로고    scopus 로고
    • ER stress activates the NLRP3 inflammasome via an UPRindependent pathway
    • Menu, P. et al. ER stress activates the NLRP3 inflammasome via an UPRindependent pathway. Cell Death Dis. 3, e261 (2012).
    • (2012) Cell Death Dis. , vol.3 , pp. e261
    • Menu, P.1
  • 34
  • 35
    • 81055125976 scopus 로고    scopus 로고
    • The potential role of interleukin-17 in severe asthma
    • Wang, Y.-H. & Wills-Karp, M. The potential role of interleukin-17 in severe asthma. Curr. Allergy Asthma Rep. 11, 388-394 (2011).
    • (2011) Curr. Allergy Asthma Rep. , vol.11 , pp. 388-394
    • Wang, Y.-H.1    Wills-Karp, M.2
  • 36
    • 75949114864 scopus 로고    scopus 로고
    • Critical role of IL-17RA in immunopathology of influenza infection
    • Crowe, C.R. et al. Critical role of IL-17RA in immunopathology of influenza infection. J. Immunol. 183, 5301-5310 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 5301-5310
    • Crowe, C.R.1
  • 37
    • 84886023028 scopus 로고    scopus 로고
    • Local IL-17A potentiates early neutrophil recruitment to the respiratory tract during severe RSV infection
    • Stoppelenburg, A.J. et al. Local IL-17A potentiates early neutrophil recruitment to the respiratory tract during severe RSV infection. PLoS One 8, e78461 (2013).
    • (2013) PLoS One , vol.8 , pp. e78461
    • Stoppelenburg, A.J.1
  • 38
    • 84860997738 scopus 로고    scopus 로고
    • Specific increase in local IL-17 production during recovery from primary RSV bronchiolitis
    • Faber, T.E., Groen, H., Welfing, M., Jansen, K.J.G. & Bont, L.J. Specific increase in local IL-17 production during recovery from primary RSV bronchiolitis. J. Med. Virol. 84, 1084-1088 (2012).
    • (2012) J. Med. Virol. , vol.84 , pp. 1084-1088
    • Faber, T.E.1    Groen, H.2    Welfing, M.3    Jansen, K.J.G.4    Bont, L.J.5
  • 39
    • 0037592950 scopus 로고    scopus 로고
    • Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop
    • Chen, Y. et al. Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop. J. Biol. Chem. 278, 17036-17043 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 17036-17043
    • Chen, Y.1
  • 40
    • 67349269904 scopus 로고    scopus 로고
    • Autophagy enhances the presentation of endogenous viral antigens on MHC class i molecules during HSV-1 infection
    • English, L. et al. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat. Immunol. 10, 480-487 (2009).
    • (2009) Nat. Immunol. , vol.10 , pp. 480-487
    • English, L.1
  • 41
    • 79958765451 scopus 로고    scopus 로고
    • Alternative pathways for MHC class i presentation: A new function for autophagy
    • Chemali, M., Radtke, K., Desjardins, M. & English, L. Alternative pathways for MHC class I presentation: a new function for autophagy. Cell. Mol. Life Sci. 68, 1533-1541 (2011).
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 1533-1541
    • Chemali, M.1    Radtke, K.2    Desjardins, M.3    English, L.4
  • 42
    • 33846461678 scopus 로고    scopus 로고
    • A critical role for the autophagy gene Atg5 in Tcell survival and proliferation
    • Pua, H.H., Dzhagalov, I., Chuck, M., Mizushima, N. & He, Y.-W. A critical role for the autophagy gene Atg5 in Tcell survival and proliferation. J. Exp. Med. 204, 25-31 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 25-31
    • Pua, H.H.1    Dzhagalov, I.2    Chuck, M.3    Mizushima, N.4    He, Y.-W.5
  • 43
    • 64249123646 scopus 로고    scopus 로고
    • Autophagy isessential formitochondrial clearance in mature T lymphocytes
    • Pua,H.H.,Guo,J.,Komatsu,M. & He,Y.-W.Autophagy isessential formitochondrial clearance in mature T lymphocytes. J. Immunol. 182, 4046-4055 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 4046-4055
    • Pua, H.H.1    Guo, J.2    Komatsu, M.3    He, Y.-W.4
  • 44
    • 84887446052 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation
    • Heid, M.E. et al. Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. J. Immunol. 191, 5230-5238 (2013).
    • (2013) J. Immunol. , vol.191 , pp. 5230-5238
    • Heid, M.E.1
  • 45
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou, R., Yazdi, A.S., Menu, P. & Tschopp, J. A role for mitochondria in NLRP3 inflammasome activation. Nature 469, 221-225 (2011).
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4
  • 46
    • 84893451103 scopus 로고    scopus 로고
    • Ciliary dyskinesia is an early feature of respiratory syncytial virus infection
    • Smith, C.M. et al. Ciliary dyskinesia is an early feature of respiratory syncytial virus infection. Eur. Respir. J. 43, 485-496 (2013).
    • (2013) Eur. Respir. J. , vol.43 , pp. 485-496
    • Smith, C.M.1
  • 47
    • 33845459165 scopus 로고    scopus 로고
    • Autophagy is activated for cell survival after endoplasmic reticulum stress
    • Ogata, M. et al. Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol. Cell Biol. 26, 9220-9231 (2006).
    • (2006) Mol. Cell Biol. , vol.26 , pp. 9220-9231
    • Ogata, M.1
  • 48
    • 33749579383 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress triggers autophagy
    • Yorimitsu, T., Nair, U., Yang, Z. & Klionsky, D.J. Endoplasmic reticulum stress triggers autophagy. J. Biol. Chem. 281, 30299-30304 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 30299-30304
    • Yorimitsu, T.1    Nair, U.2    Yang, Z.3    Klionsky, D.J.4
  • 49
    • 80455173839 scopus 로고    scopus 로고
    • BAX inhibitor-1 regulates autophagy by controlling the IRE1a branch of the unfolded protein response
    • Castillo,K. et al.BAX inhibitor-1 regulates autophagy by controlling the IRE1a branch of the unfolded protein response. EMBO J. 30, 4465-4478 (2011).
    • (2011) EMBO J. , vol.30 , pp. 4465-4478
    • Castillo, K.1
  • 50
    • 2142808245 scopus 로고    scopus 로고
    • Respiratory syncytial virus-induced chemokine production: Linking viral replication to chemokine production in vitro and in vivo
    • Miller, A.L., Bowlin, T.L. & Lukacs, N.W. Respiratory syncytial virus-induced chemokine production: linking viral replication to chemokine production in vitro and in vivo. J. Infect. Dis. 189, 1419-1430 (2004).
    • (2004) J. Infect. Dis. , vol.189 , pp. 1419-1430
    • Miller, A.L.1    Bowlin, T.L.2    Lukacs, N.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.