Sensing Cardiac Electrical Activity with a Cardiac Myocyte-Targeted Optogenetic Voltage Indicator

Circulation Research

Volumn 117, Issue 5, 2015, Pages 401-412

  Liao, Mei Ling Chang ^a,c,d   De Boer, Teun P ^e   Mutoh, Hiroki ^f   Raad, Nour ^b,c,g   Richter, Claudia ^g   Wagner, Eva ^b,c   Downie, Bryan R ^a   Unsöld, Bernhard ^b,i   Arooj, Iqra ^e   Streckfuss Bömeke, Katrin ^b,c   Döker, Stephan ^a   Luther, Stefan ^c,g   Guan, Kaomei ^b,c   Wagner, Stefan ^b,h,i   Lehnart, Stephan E ^b,c   Maier, Lars S ^b,i   Stühmer, Walter ^c   Wettwer, Erich ^a   Van Veen, Toon ^e   Morlock, Michael M ^d   Knöpfel, Thomas ^f,j   Zimmermann, Wolfram Hubertus ^a,c   more..

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b Clinic for Cardiology and Pulmonology   (United States)

^c DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^d HAMBURG UNIVERSITY OF TECHNOLOGY   (Germany)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^g Max Planck Institutes for Dynamics and Self Organization   (Germany)

^h MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

ⁱ UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^j IMPERIAL COLLEGE LONDON   (United Kingdom)

more..

Author keywords

arrhythmias, cardiac; electrophysiology; heart; myocytes, cardiac; optical imaging; optogenetics; stem cells

Indexed keywords

CALCIUM CHANNEL L TYPE; FLUORESCENT DYE; MYOSIN HEAVY CHAIN ALPHA; PEPTIDES AND PROTEINS; RYANODINE RECEPTOR 2; UNCLASSIFIED DRUG; VOLTAGE SENSITIVE FLUORESCENCE PROTEIN 2.3;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CELL MATURATION; CONTROLLED STUDY; ECHOCARDIOGRAPHY; EMBRYO; EX VIVO STUDY; EXCITATION CONTRACTION COUPLING; FEMALE; FIBER OPTICS; HEART ARRHYTHMIA; HEART EXCITATION; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HEART MUSCLE POTENTIAL; HEART RATE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OPTOGENETICS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SARCOPLASMIC RETICULUM; VOLTAGE SENSITIVE DYE IMAGING; ANIMAL; HUMAN; MEMBRANE POTENTIAL; PHYSIOLOGY; PROCEDURES; TRANSGENIC MOUSE;

ANIMALS; HUMANS; MEMBRANE POTENTIALS; MICE; MICE, TRANSGENIC; MYOCYTES, CARDIAC; OPTOGENETICS; VOLTAGE-SENSITIVE DYE IMAGING;

EID: 84939551716     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.117.306143     Document Type: Article

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