메뉴 건너뛰기




Volumn 128, Issue 15, 2015, Pages 3055-3067

The homeobox gene DLX4 regulates erythro-megakaryocytic differentiation by stimulating IL-1ß and NF-κB signaling

Author keywords

Cytokine; Erythroid; Homeobox gene; Megakaryocyte; NF B

Indexed keywords

HEMOGLOBIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DLX4; UNCLASSIFIED DRUG; DLX4 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; IL1B PROTEIN, HUMAN;

EID: 84939543314     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.168187     Document Type: Article
Times cited : (13)

References (58)
  • 2
    • 50949090908 scopus 로고    scopus 로고
    • EKLF restricts megakaryocytic differentiation at the benefit of erythrocytic differentiation
    • Bouilloux, F., Juban, G., Cohet, N., Buet, D., Guyot, B., Vainchenker, W., Louache, F. and Morlé, F. (2008). EKLF restricts megakaryocytic differentiation at the benefit of erythrocytic differentiation. Blood 112, 576-584.
    • (2008) Blood , vol.112 , pp. 576-584
    • Bouilloux, F.1    Juban, G.2    Cohet, N.3    Buet, D.4    Guyot, B.5    Vainchenker, W.6    Louache, F.7    Morlé, F.8
  • 4
    • 84864072058 scopus 로고    scopus 로고
    • Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation
    • Cai, M., Langer, E. M., Gill, J. G., Satpathy, A. T., Albring, J. C., Murphy, T. L. and Murphy, K. M. (2012). Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation. Blood 120, 335-346.
    • (2012) Blood , vol.120 , pp. 335-346
    • Cai, M.1    Langer, E.M.2    Gill, J.G.3    Satpathy, A.T.4    Albring, J.C.5    Murphy, T.L.6    Murphy, K.M.7
  • 5
    • 77954232924 scopus 로고    scopus 로고
    • Protein-arginine methyltransferase 1 suppresses megakaryocytic differentiation via modulation of the p38 MAPK pathway in K562 cells
    • Chang, Y.-I., Hua, W.-K., Yao, C.-L., Hwang, S.-M., Hung, Y.-C., Kuan, C.-J., Leou, J.-S. and Lin, W.-J. (2010). Protein-arginine methyltransferase 1 suppresses megakaryocytic differentiation via modulation of the p38 MAPK pathway in K562 cells. J. Biol. Chem. 285, 20595-20606.
    • (2010) J. Biol. Chem. , vol.285 , pp. 20595-20606
    • Chang, Y.-I.1    Hua, W.-K.2    Yao, C.-L.3    Hwang, S.-M.4    Hung, Y.-C.5    Kuan, C.-J.6    Leou, J.-S.7    Lin, W.-J.8
  • 8
    • 0033566308 scopus 로고    scopus 로고
    • Constitutive HOXA5 expression inhibits erythropoiesis and increases myelopoiesis from human hematopoietic progenitors
    • Crooks, G. M., Fuller, J., Petersen, D., Izadi, P., Malik, P., Pattengale, P. K., Kohn, D. B. and Gasson, J. C. (1999). Constitutive HOXA5 expression inhibits erythropoiesis and increases myelopoiesis from human hematopoietic progenitors. Blood 94, 519-528.
    • (1999) Blood , vol.94 , pp. 519-528
    • Crooks, G.M.1    Fuller, J.2    Petersen, D.3    Izadi, P.4    Malik, P.5    Pattengale, P.K.6    Kohn, D.B.7    Gasson, J.C.8
  • 9
    • 0142124320 scopus 로고    scopus 로고
    • Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor
    • Dahl, R., Walsh, J. C., Lancki, D., Laslo, P., Iyer, S. R., Singh, H. and Simon, M. C. (2003). Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor. Nat. Immunol. 4, 1029-1036.
    • (2003) Nat. Immunol. , vol.4 , pp. 1029-1036
    • Dahl, R.1    Walsh, J.C.2    Lancki, D.3    Laslo, P.4    Iyer, S.R.5    Singh, H.6    Simon, M.C.7
  • 14
    • 78650671103 scopus 로고    scopus 로고
    • Hoxa9 regulates Flt3 in lymphohematopoietic progenitors
    • Gwin, K., Frank, E., Bossou, A. and Medina, K. L. (2010). Hoxa9 regulates Flt3 in lymphohematopoietic progenitors. J. Immunol. 185, 6572-6583.
    • (2010) J. Immunol. , vol.185 , pp. 6572-6583
    • Gwin, K.1    Frank, E.2    Bossou, A.3    Medina, K.L.4
  • 16
    • 0037417892 scopus 로고    scopus 로고
    • The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12
    • Hall, M. A., Curtis, D. J., Metcalf, D., Elefanty, A. G., Sourris, K., Robb, L., Gothert, J. R., Jane, S. M. and Begley, C. G. (2003). The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12. Proc. Natl. Acad. Sci. USA 100, 992-997.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 992-997
    • Hall, M.A.1    Curtis, D.J.2    Metcalf, D.3    Elefanty, A.G.4    Sourris, K.5    Robb, L.6    Gothert, J.R.7    Jane, S.M.8    Begley, C.G.9
  • 17
    • 0029121366 scopus 로고
    • PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene
    • Hohaus, S., Petrovick, M. S., Voso, M. T., Sun, Z., Zhang, D. E. and Tenen, D. G. (1995). PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene. Mol. Cell. Biol. 15, 5830-5845.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5830-5845
    • Hohaus, S.1    Petrovick, M.S.2    Voso, M.T.3    Sun, Z.4    Zhang, D.E.5    Tenen, D.G.6
  • 18
    • 33646490285 scopus 로고    scopus 로고
    • Lineage-specific hematopoietic growth factors
    • Kaushansky, K. (2006). Lineage-specific hematopoietic growth factors. N. Eng. J. Med. 354, 2034-2045.
    • (2006) N. Eng. J. Med. , vol.354 , pp. 2034-2045
    • Kaushansky, K.1
  • 19
    • 0025647249 scopus 로고
    • Interleukin-1 beta (IL-1 beta) induces thrombocytosis in mice: possible implication of IL-6
    • Kimura, H., Ishibashi, T., Shikama, Y., Okano, A., Akiyama, Y., Uchida, T. and Maruyama, Y. (1990). Interleukin-1 beta (IL-1 beta) induces thrombocytosis in mice: possible implication of IL-6. Blood 76, 2493-2500.
    • (1990) Blood , vol.76 , pp. 2493-2500
    • Kimura, H.1    Ishibashi, T.2    Shikama, Y.3    Okano, A.4    Akiyama, Y.5    Uchida, T.6    Maruyama, Y.7
  • 20
    • 34548008184 scopus 로고    scopus 로고
    • Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: clinical and therapeutic implications
    • Lambert, M. P., Rauova, L., Bailey, M., Sola-Visner, M. C., Kowalska, M. A. and Poncz, M. (2007). Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: clinical and therapeutic implications. Blood 110, 1153-1160.
    • (2007) Blood , vol.110 , pp. 1153-1160
    • Lambert, M.P.1    Rauova, L.2    Bailey, M.3    Sola-Visner, M.C.4    Kowalska, M.A.5    Poncz, M.6
  • 21
    • 0038819964 scopus 로고    scopus 로고
    • Erythroid gene suppression by NF-kappa B
    • Liu, J.-J., Hou, S.-C. and Shen, C.-K. J. (2003). Erythroid gene suppression by NF-kappa B. J. Biol. Chem. 278, 19534-19540.
    • (2003) J. Biol. Chem. , vol.278 , pp. 19534-19540
    • Liu, J.-J.1    Hou, S.-C.2    Shen, C.-K.J.3
  • 23
    • 84880010050 scopus 로고    scopus 로고
    • The incredible journey: from megakaryocyte development to platelet formation
    • Machlus, K. R. and Italiano, J. E. (2013). The incredible journey: from megakaryocyte development to platelet formation. J. Cell Biol. 201, 785-796.
    • (2013) J. Cell Biol. , vol.201 , pp. 785-796
    • Machlus, K.R.1    Italiano, J.E.2
  • 25
    • 0036464649 scopus 로고    scopus 로고
    • Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release
    • Mattia, G., Vulcano, F., Milazzo, L., Barca, A., Macioce, G., Giampaolo, A. and Hassan, H. J. (2002). Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release. Blood 99, 888-897.
    • (2002) Blood , vol.99 , pp. 888-897
    • Mattia, G.1    Vulcano, F.2    Milazzo, L.3    Barca, A.4    Macioce, G.5    Giampaolo, A.6    Hassan, H.J.7
  • 26
    • 0026504525 scopus 로고
    • Homeobox genes and axial patterning
    • McGinnis,W. and Krumlauf, R. (1992). Homeobox genes and axial patterning. Cell 68, 283-302.
    • (1992) Cell , vol.68 , pp. 283-302
    • McGinnis, W.1    Krumlauf, R.2
  • 27
    • 0026526803 scopus 로고
    • Inhibition of human erythroid colony-forming units by interleukin-1 is mediated by gamma interferon
    • Means, R. T., Dessypris, E. N. and Krantz, S. B. (1992). Inhibition of human erythroid colony-forming units by interleukin-1 is mediated by gamma interferon. J. Cell Physiol. 150, 59-64.
    • (1992) J. Cell Physiol. , vol.150 , pp. 59-64
    • Means, R.T.1    Dessypris, E.N.2    Krantz, S.B.3
  • 32
    • 0038115243 scopus 로고    scopus 로고
    • Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene
    • Okada, Y., Nagai, R., Sato, T., Matsuura, E., Minami, T., Morita, I. and Doi, T. (2003). Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene. Blood 101, 4748-4756.
    • (2003) Blood , vol.101 , pp. 4748-4756
    • Okada, Y.1    Nagai, R.2    Sato, T.3    Matsuura, E.4    Minami, T.5    Morita, I.6    Doi, T.7
  • 33
    • 70349684846 scopus 로고    scopus 로고
    • Integrating extrinsic and intrinsic cues into a minimal model of lineage commitment for hematopoietic progenitors
    • Palani, S. and Sarkar, C. A. (2009). Integrating extrinsic and intrinsic cues into a minimal model of lineage commitment for hematopoietic progenitors. PLoS Comput. Biol. 5, e1000518.
    • (2009) PLoS Comput. Biol. , vol.5
    • Palani, S.1    Sarkar, C.A.2
  • 34
    • 0036796883 scopus 로고    scopus 로고
    • Developmental functions of the Distal-less/Dlx homeobox genes
    • Panganiban, G. and Rubenstein, J. L. (2002). Developmental functions of the Distal-less/Dlx homeobox genes. Development 129, 4371-4386.
    • (2002) Development , vol.129 , pp. 4371-4386
    • Panganiban, G.1    Rubenstein, J.L.2
  • 35
    • 84856213846 scopus 로고    scopus 로고
    • The diverse and complex roles of NF-κB subunits in cancer
    • Perkins, N. D. (2012). The diverse and complex roles of NF-κB subunits in cancer. Nat. Rev. Cancer 12, 121-132.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 121-132
    • Perkins, N.D.1
  • 36
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl, M.W. (2001). A new mathematical model for relative quantification in real-time RT-PCR. Nucl. Acids Res. 29, e45.
    • (2001) Nucl. Acids Res. , vol.29 , pp. e45
    • Pfaffl, M.W.1
  • 37
    • 0030772376 scopus 로고    scopus 로고
    • Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
    • Pierce, J.W., Schoenleber, R., Jesmok, G., Best, J., Moore, S. A., Collins, T. and Gerritsen, M. E. (1997). Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J. Biol. Chem. 272, 21096-21103.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21096-21103
    • Pierce, J.W.1    Schoenleber, R.2    Jesmok, G.3    Best, J.4    Moore, S.A.5    Collins, T.6    Gerritsen, M.E.7
  • 38
    • 77950986252 scopus 로고    scopus 로고
    • Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage
    • Randrianarison-Huetz, V., Laurent, B., Bardet, V., Blobe, G. C., Huetz, F. and Duménil, D. (2010). Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage. Blood 115, 2784-2795.
    • (2010) Blood , vol.115 , pp. 2784-2795
    • Randrianarison-Huetz, V.1    Laurent, B.2    Bardet, V.3    Blobe, G.C.4    Huetz, F.5    Duménil, D.6
  • 41
    • 0023610252 scopus 로고
    • Tumor necrosis factor-alpha and hematopoietic progenitors: effects of tumor necrosis factor on the growth of erythroid progenitors CFU-E and BFU-E and the hematopoietic cell lines K562, HL60 and HEL cells
    • Roodman, G. D., Bird, A., Hutzler, D. and Montgomery, W. (1987). Tumor necrosis factor-alpha and hematopoietic progenitors: effects of tumor necrosis factor on the growth of erythroid progenitors CFU-E and BFU-E and the hematopoietic cell lines K562, HL60 and HEL cells. Exp. Hematol. 15, 928-935.
    • (1987) Exp. Hematol. , vol.15 , pp. 928-935
    • Roodman, G.D.1    Bird, A.2    Hutzler, D.3    Montgomery, W.4
  • 42
    • 82555172154 scopus 로고    scopus 로고
    • Integration of cytokine and transcription factor signals in hematopoietic stem cell commitment
    • Sarrazin, S. and Sieweke, M. (2011). Integration of cytokine and transcription factor signals in hematopoietic stem cell commitment. Semin. Immunol. 23, 326-334.
    • (2011) Semin. Immunol. , vol.23 , pp. 326-334
    • Sarrazin, S.1    Sieweke, M.2
  • 43
    • 0024847874 scopus 로고
    • In vivo treatment with erythroid differentiation factor (EDF/activin A) increases erythroid precursors (CFU-E and BFU-E) in mice
    • Shiozaki, M., Sakai, R., Tabuchi, M., Eto, Y., Kosaka, M. and Shibai, H. (1989). In vivo treatment with erythroid differentiation factor (EDF/activin A) increases erythroid precursors (CFU-E and BFU-E) in mice. Biochem. Biophys. Res.Comm. 165, 1155-1161.
    • (1989) Biochem. Biophys. Res.Comm. , vol.165 , pp. 1155-1161
    • Shiozaki, M.1    Sakai, R.2    Tabuchi, M.3    Eto, Y.4    Kosaka, M.5    Shibai, H.6
  • 45
    • 0029793902 scopus 로고    scopus 로고
    • PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells
    • Smith, L. T., Hohaus, S., Gonzalez, D. A., Dziennis, S. E. and Tenen, D. G. (1996). PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells. Blood 88, 1234-1247.
    • (1996) Blood , vol.88 , pp. 1234-1247
    • Smith, L.T.1    Hohaus, S.2    Gonzalez, D.A.3    Dziennis, S.E.4    Tenen, D.G.5
  • 46
  • 48
    • 0032528484 scopus 로고    scopus 로고
    • Role of GATA-1 in proliferation and differentiation of definitive erythroid and megakaryocytic cells in vivo
    • Takahashi, S., Komeno, T., Suwabe, N., Yoh, K., Nakajima, O., Nishimura, S., Kuroha, T., Nagasawa, T. and Yamamoto, M. (1998). Role of GATA-1 in proliferation and differentiation of definitive erythroid and megakaryocytic cells in vivo. Blood 92, 434-442.
    • (1998) Blood , vol.92 , pp. 434-442
    • Takahashi, S.1    Komeno, T.2    Suwabe, N.3    Yoh, K.4    Nakajima, O.5    Nishimura, S.6    Kuroha, T.7    Nagasawa, T.8    Yamamoto, M.9
  • 50
    • 79958776867 scopus 로고    scopus 로고
    • Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-ß cytostatic program and blocks the antiproliferative effect of TGF-ß
    • Trinh, B. Q., Barengo, N. and Naora, H. (2011). Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-ß cytostatic program and blocks the antiproliferative effect of TGF-ß. Oncogene 30, 2718-2729.
    • (2011) Oncogene , vol.30 , pp. 2718-2729
    • Trinh, B.Q.1    Barengo, N.2    Naora, H.3
  • 51
    • 0031472234 scopus 로고    scopus 로고
    • FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation
    • Tsang, A. P., Visvader, J. E., Turner, C. A., Fujiwara, Y., Yu, C., Weiss, M. J., Crossley, M. and Orkin, S. H. (1997). FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell 90, 109-119.
    • (1997) Cell , vol.90 , pp. 109-119
    • Tsang, A.P.1    Visvader, J.E.2    Turner, C.A.3    Fujiwara, Y.4    Yu, C.5    Weiss, M.J.6    Crossley, M.7    Orkin, S.H.8
  • 52
    • 0032821235 scopus 로고    scopus 로고
    • A combination of megakaryocyte growth and development factor and interleukin-1 is sufficient to culture large numbers of megakaryocytic progenitors and megakaryocytes for transfusion purposes
    • van den Oudenrijn, S., de Haas, M., Calafat, J., van der Schoot, C. E. and von dem Borne, A. E. G. (1999). A combination of megakaryocyte growth and development factor and interleukin-1 is sufficient to culture large numbers of megakaryocytic progenitors and megakaryocytes for transfusion purposes. Br. J. Haematol. 106, 553-563.
    • (1999) Br. J. Haematol. , vol.106 , pp. 553-563
    • van den Oudenrijn, S.1    de Haas, M.2    Calafat, J.3    van der Schoot, C.E.4    von dem Borne, A.E.G.5
  • 53
    • 0031000626 scopus 로고    scopus 로고
    • Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase
    • Whalen, A. M., Galasinski, S. C., Shapiro, P. S., Nahreini, T. S. and Ahn, N. G. (1997). Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase. Mol. Cell. Biol. 17, 1947-1958.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1947-1958
    • Whalen, A.M.1    Galasinski, S.C.2    Shapiro, P.S.3    Nahreini, T.S.4    Ahn, N.G.5
  • 54
    • 0348143180 scopus 로고    scopus 로고
    • A random variance model for detection of differential gene expression in small microarray experiments
    • Wright, G. W. and Simon, R. M. (2003). A random variance model for detection of differential gene expression in small microarray experiments. Bioinformatics 19, 2448-2455.
    • (2003) Bioinformatics , vol.19 , pp. 2448-2455
    • Wright, G.W.1    Simon, R.M.2
  • 55
    • 0023598057 scopus 로고
    • Importance of FSH-releasing protein and inhibin in erythrodifferentiation
    • Yu, J., Shao, L.-E., Lemas, V., Yu, A. L., Vaughan, J., Rivier, J. and Vale, W. (1987). Importance of FSH-releasing protein and inhibin in erythrodifferentiation. Nature 330, 765-767.
    • (1987) Nature , vol.330 , pp. 765-767
    • Yu, J.1    Shao, L.-E.2    Lemas, V.3    Yu, A.L.4    Vaughan, J.5    Rivier, J.6    Vale, W.7
  • 57
    • 0028120907 scopus 로고
    • The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor
    • Zhang, D. E., Hetherington, C. J., Chen, H. M. and Tenen, D. G. (1994). The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor. Mol. Cell. Biol. 14, 373-381.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 373-381
    • Zhang, D.E.1    Hetherington, C.J.2    Chen, H.M.3    Tenen, D.G.4
  • 58
    • 0025786584 scopus 로고
    • Activation of the erythropoietin receptor promoter by transcription factor GATA-1
    • Zon, L. I., Youssoufian, H., Mather, C., Lodish, H. F. and Orkin, S. H. (1991). Activation of the erythropoietin receptor promoter by transcription factor GATA-1. Proc. Natl. Acad. Sci. USA 88, 10638-10641.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10638-10641
    • Zon, L.I.1    Youssoufian, H.2    Mather, C.3    Lodish, H.F.4    Orkin, S.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.