Endothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells

Journal of Cell Science

Volumn 128, Issue 15, 2015, Pages 2983-2988

  Ding, Bi Sen ^a   Gomi, Kazunori ^a   Rafii, Shahin ^a   Crystal, Ronald G ^a   Walters, Matthew S ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Airway basal cell; Crosstalk; Endothelial cell; MMP14; Progenitor cell

Indexed keywords

ENDOTHELIAL CELL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 11; FIBROBLAST GROWTH FACTOR 13; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 5; MATRIX METALLOPROTEINASE 14; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VASCULOTROPIN A; FGF5 PROTEIN, HUMAN; FGFR1 PROTEIN, HUMAN; FIBROBLAST GROWTH FACTOR RECEPTOR 1; LIGAND; MMP14 PROTEIN, HUMAN;

ANCHORAGE INDEPENDENT GROWTH; ANTIBODY MEDIATED REJECTION; ARTICLE; CELL INTERACTION; CELL PROLIFERATION; CELL STIMULATION; COCULTURE; CONTROLLED STUDY; EPITHELIUM BASAL CELL; GENE SILENCING; HUMAN; HUMAN CELL; LUNG ENDOTHELIUM; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY EPITHELIUM; RNA SEQUENCE; SEQUENCE ANALYSIS; STEM CELL CULTURE; UMBILICAL VEIN ENDOTHELIAL CELL; BASEMENT MEMBRANE; BIOSYNTHESIS; CYTOLOGY; ENDOTHELIUM CELL; GENETICS; HIGH THROUGHPUT SEQUENCING; METABOLISM; STROMA CELL;

BASEMENT MEMBRANE; CELL PROLIFERATION; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 5; FIBROBLAST GROWTH FACTORS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LIGANDS; MATRIX METALLOPROTEINASE 14; PARACRINE COMMUNICATION; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; STROMAL CELLS;

EID: 84939542069     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.168179     Document Type: Article

References (25)

1. Allerstorfer, S., Sonvilla, G., Fischer, H., Spiegl-Kreinecker, S., Gauglhofer, C., Setinek, U., Czech, T., Marosi, C., Buchroithner, J., Pichler, J. et al. (2008). FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities. Oncogene 27, 4180-4190.
2. Belov, A. A. and Mohammadi, M. (2013). Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology. Cold Spring Harb. Perspect. Biol. 5, a015958.
3. Carter, E. P., Fearon, A. E. and Grose, R. P. (2015). Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction. Trends Cell Biol. 25, 221-233.
4. Crystal, R. G., Randell, S. H., Engelhardt, J. F., Voynow, J. and Sunday, M. E. (2008). Airway epithelial cells: current concepts and challenges. Proc. Am. Thorac. Soc. 5, 772-777.
5. Curradi, G.,Walters, M. S., Ding, B.-S., Rafii, S., Hackett, N. R. and Crystal, R. G. (2012). Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells. Cell. Mol. Life Sci. 69, 2217-2231.
6. Ding, B.-S., Nolan, D. J., Guo, P., Babazadeh, A. O., Cao, Z., Rosenwaks, Z., Crystal, R. G., Simons, M., Sato, T. N., Worgall, S. et al. (2011). Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell 147, 539-553.
7. Evans, M. J., Van Winkle, L. S., Fanucchi, M. V. and Plopper, C. G. (2001). Cellular and molecular characteristics of basal cells in airway epithelium. Exp. Lung Res. 27, 401-415.
8. Hackett, N. R., Shaykhiev, R., Walters, M. S., Wang, R., Zwick, R. K., Ferris, B., Witover, B., Salit, J. and Crystal, R. G. (2011). The human airway epithelial basal cell transcriptome. PLoS ONE 6, e18378.
9. Hajj, R., Baranek, T., Le Naour, R., Lesimple, P., Puchelle, E. and Coraux, C. (2007). Basal cells of the human adult airway surface epithelium retain transitamplifying cell properties. Stem Cells 25, 139-148.
10. Hogan, B. L. M., Barkauskas, C. E., Chapman, H. A., Epstein, J. A., Jain, R., Hsia, C. C.W., Niklason, L., Calle, E., Le, A., Randell, S. H. et al. (2014). Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function. Cell Stem Cell 15, 123-138.
11. Knight, D. A. and Holgate, S. T. (2003). The airway epithelium: structural and functional properties in health and disease. Respirology 8, 432-446.
12. Kobayashi, H., Butler, J.M.,O'Donnell,R.,Kobayashi,M., Ding,B.-S.,Bonner, B., Chiu, V. K., Nolan, D. J., Shido, K., Benjamin, L. et al. (2010). Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Nat. Cell Biol. 12, 1046-1056.
13. Kranenburg, A. R., de Boer, W. I., Van Krieken, J. H., Mooi, W. J., Walters, J. E., Saxena, P. R., Sterk, P. J. and Sharma, H. S. (2002). Enhanced expression of fibroblast growth factors and receptor FGFR-1 during vascular remodeling in chronic obstructive pulmonary disease. Am. J. Respir. Cell Mol. Biol. 27, 517-525.
14. Kranenburg, A. R., Willems-Widyastuti, A., Mooi, W. J., Saxena, P. R., Sterk, P. J., de Boer, W. I. and Sharma, H. S. (2005). Chronic obstructive pulmonary disease is associated with enhanced bronchial expression of FGF-1, FGF-2, and FGFR-1. J. Pathol. 206, 28-38.
15. Lieu, C., Heymach, J., Overman, M., Tran, H. and Kopetz, S. (2011). Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis. Clin. Cancer Res. 17, 6130-6139.
16. Olsen, S. K., Garbi, M., Zampieri, N., Eliseenkova, A. V., Ornitz, D. M., Goldfarb, M. and Mohammadi, M. (2003). Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs. J. Biol. Chem. 278, 34226-34236.
17. Presta, M., Dell'Era, P., Mitola, S., Moroni, E., Ronca, R. and Rusnati, M. (2005). Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. Cytokine Growth Factor Rev. 16, 159-178.
18. Rock, J. R., Onaitis, M. W., Rawlins, E. L., Lu, Y., Clark, C. P., Xue, Y., Randell, S. H. and Hogan, B. L. M. (2009). Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc. Natl. Acad. Sci. USA 106, 12771-12775.
19. Rock, J. R., Randell, S. H. and Hogan, B. L. M. (2010). Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling. Dis. Model. Mech. 3, 545-556.
20. Ryan, D. M.,Vincent,T. L.,Salit, J.,Walters,M. S.,Agosto-Perez, F.,Shaykhiev, R., Strulovici-Barel, Y., Downey, R. J., Buro-Auriemma, L. J., Staudt, M. R. et al. (2014). Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2. PLoS ONE 9, e88051.
21. Shaykhiev, R., Zuo, W.-L., Chao, I., Fukui, T., Witover, B., Brekman, A. and Crystal, R. G. (2013). EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype. Proc. Natl. Acad. Sci. USA 110, 12102-12107.
22. Soltani, A., Reid, D. W., Sohal, S. S., Wood-Baker, R., Weston, S., Muller, H. K. and Walters, E. H. (2010). Basement membrane and vascular remodelling in smokers and chronic obstructive pulmonary disease: a cross-sectional study. Respir. Res. 11, 105.
23. Staudt, M. R., Buro-Auriemma, L. J., Walters, M. S., Salit, J., Vincent, T., Shaykhiev, R., Mezey, J. G., Tilley, A. E., Kaner, R. J., Ho, M.W. Y. et al. (2014). Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 190, 955-958.
24. Tam, A., Wadsworth, S., Dorscheid, D., Man, S. F. P. and Sin, D. D. (2011). The airway epithelium: more than just a structural barrier. Ther. Adv. Respir. Dis. 5, 255-273.
25. Walters, M. S.,Gomi, K., Ashbridge, B., Moore,M.A. S., Arbelaez, V., Heldrich, J., Ding, B.-S., Rafii, S., Staudt, M. R. and Crystal, R. G. (2013). Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity. Respir. Res. 14, 135.