Personalized medicine in gastrointestinal stromal tumor (GIST): Clinical implications of the somatic and germline DNA analysis

International Journal of Molecular Sciences

Volumn 16, Issue 7, 2015, Pages 15592-15608

  Ravegnini, Gloria ^a   Nannini, Margherita ^b   Sammarini, Giulia ^a   Astolfi, Annalisa ^a   Biasco, Guido ^a,b   Pantaleo, Maria A ^a,b   Hrelia, Patrizia ^a   Angelini, Sabrina ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Biomarkers; Drug resistance; GIST; KIT PDGFRA mutant GIST; Personalized therapy; Polymorphisms; WT GIST

Indexed keywords

IMATINIB; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN TYROSINE KINASE INHIBITOR; REGORAFENIB; SUNITINIB; DNA; PROTEIN KINASE INHIBITOR; STEM CELL FACTOR RECEPTOR;

CLINICAL TRIAL (TOPIC); DNA DETERMINATION; DRUG EFFICACY; DRUG SAFETY; GASTROINTESTINAL STROMAL TUMOR; GENOTYPE; HUMAN; LIFE EXPECTANCY; MOLECULAR GENETICS; NEXT GENERATION SEQUENCING; PERSONALIZED MEDICINE; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; ANTAGONISTS AND INHIBITORS; GASTROINTESTINAL NEOPLASMS; GASTROINTESTINAL STROMAL TUMORS; GENETICS; METABOLISM; PATHOLOGY;

DNA, NEOPLASM; GASTROINTESTINAL NEOPLASMS; GASTROINTESTINAL STROMAL TUMORS; HUMANS; IMATINIB MESYLATE; PRECISION MEDICINE; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA;

EID: 84939529271     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160715592     Document Type: Review

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