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Volumn 51, Issue 3, 2013, Pages 523-534

The 'golden age' of DNA methylation in neurodegenerative diseases

(1)  Fuso, Andrea a  

a NONE

Author keywords

DNA methylation; Epigenetic assays; Epigenetics; Human disease; Neurodegeneration; One carbon metabolism

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID PRECURSOR PROTEIN; BETA GLUCOSIDASE; CHOLINE; CYANOCOBALAMIN; CYTOSINE; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; FOLIC ACID; FRAGILE X MENTAL RETARDATION PROTEIN; GENOMIC DNA; HOMOCYSTEINE; HUNTINGTIN; LEUCINE RICH REPEAT KINASE 2; PARKIN; PRESENILIN 1; PRESENILIN 2; PYRIDOXINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE;

EID: 84882417694     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2012-0618     Document Type: Conference Paper
Times cited : (41)

References (96)
  • 1
    • 0002947085 scopus 로고
    • The epigenotype
    • Waddington CH. The epigenotype. Endeavour 1942;1:18-20.
    • (1942) Endeavour , vol.1 , pp. 18-20
    • Waddington, C.H.1
  • 2
    • 0024059136 scopus 로고
    • Genomic imprinting
    • Monk M. Genomic imprinting. Genes Dev 1988;2:921-5.
    • (1988) Genes Dev , vol.2 , pp. 921-925
    • Monk, M.1
  • 4
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogs and DNA methylation
    • Jones PA, Taylor SM. Cellular differentiation, cytidine analogs and DNA methylation. Cell 1980;20:85-93.
    • (1980) Cell , vol.20 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 5
    • 0019944006 scopus 로고
    • X-chromosome inactivation in mammals
    • Martin GR. X-chromosome inactivation in mammals. Cell 1982;29:721-4.
    • (1982) Cell , vol.29 , pp. 721-724
    • Martin, G.R.1
  • 6
  • 7
    • 0025219432 scopus 로고
    • The role of DNA methylation in cancer
    • Jones PA, Buckley JD. The role of DNA methylation in cancer. Adv Cancer Res 1990;54:1-23.
    • (1990) Adv Cancer Res , vol.54 , pp. 1-23
    • Jones, P.A.1    Buckley, J.D.2
  • 8
    • 0030458551 scopus 로고    scopus 로고
    • Parental imprinting and human disease
    • Lalande M. Parental imprinting and human disease. Annu Rev Genet 1996;30:173-95.
    • (1996) Annu Rev Genet , vol.30 , pp. 173-195
    • Lalande, M.1
  • 9
    • 0034639857 scopus 로고    scopus 로고
    • Understanding the molecular basis of fragile X syndrome
    • Jin P, Warren ST. Understanding the molecular basis of fragile X syndrome. Hum Mol Genet 2000;9:901-8.
    • (2000) Hum Mol Genet , vol.9 , pp. 901-908
    • Jin, P.1    Warren, S.T.2
  • 10
    • 0033952930 scopus 로고    scopus 로고
    • Methylation moves into medicine
    • Hendrich B. Methylation moves into medicine. Curr Biol 2000;10:R60-3.
    • (2000) Curr Biol , vol.10
    • Hendrich, B.1
  • 11
    • 0033826769 scopus 로고    scopus 로고
    • Rett and ICF syndromes: Methylation moves into medicine
    • Kumar A. Rett and ICF syndromes: methylation moves into medicine. J Biosci 2000;25:213-4.
    • (2000) J Biosci , vol.25 , pp. 213-214
    • Kumar, A.1
  • 12
    • 0037068353 scopus 로고    scopus 로고
    • DNA methylation in cancer: Too much, but also too little
    • Ehrlich M. DNA methylation in cancer: too much, but also too little. Oncogene 2002;21:5400-13.
    • (2002) Oncogene , vol.21 , pp. 5400-5413
    • Ehrlich, M.1
  • 13
    • 0142153982 scopus 로고    scopus 로고
    • Profiling aberrant DNA methylation in hematologic neoplasms: A view from the tip of the iceberg
    • Esteller M. Profiling aberrant DNA methylation in hematologic neoplasms: a view from the tip of the iceberg. Clin Immunol 2003;109:80-8.
    • (2003) Clin Immunol , vol.109 , pp. 80-88
    • Esteller, M.1
  • 14
    • 1242329901 scopus 로고    scopus 로고
    • The rise and fall of genomic methylation in cancer
    • El-Osta A. The rise and fall of genomic methylation in cancer. Leukemia 2004;18:233-7.
    • (2004) Leukemia , vol.18 , pp. 233-237
    • El-Osta, A.1
  • 15
    • 79851510814 scopus 로고    scopus 로고
    • DNA methylation and cancer: Ghosts and angels above the genes
    • Sinćić N, Herceg Z. DNA methylation and cancer: ghosts and angels above the genes. Curr Opin Oncol 2011;23:69-76.
    • (2011) Curr Opin Oncol , vol.23 , pp. 69-76
    • Sinćić, N.1    Herceg, Z.2
  • 16
    • 77957350610 scopus 로고    scopus 로고
    • Identification of driver and passenger DNA methylation in cancer by epigenomic analysis
    • Kalari S, Pfeifer GP. Identification of driver and passenger DNA methylation in cancer by epigenomic analysis. Adv Genet 2010;70:277-308.
    • (2010) Adv Genet , vol.70 , pp. 277-308
    • Kalari, S.1    Pfeifer, G.P.2
  • 17
    • 77957366305 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • Kulis M, Esteller M. DNA methylation and cancer. Adv Genet 2010;70:27-56.
    • (2010) Adv Genet , vol.70 , pp. 27-56
    • Kulis, M.1    Esteller, M.2
  • 18
    • 79958285518 scopus 로고    scopus 로고
    • An introduction to epigenetics
    • Ballestar E. An introduction to epigenetics. Adv Exp Med Biol 2011;711:1-11.
    • (2011) Adv Exp Med Biol , vol.711 , pp. 1-11
    • Ballestar, E.1
  • 19
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Portela A, Esteller M. Epigenetic modifications and human disease. Nat Biotechnol 2010;28:1057-68.
    • (2010) Nat Biotechnol , vol.28 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 20
    • 14044252841 scopus 로고    scopus 로고
    • Gene-nutrient interactions in one-carbon metabolism
    • Friso S, Choi SW. Gene-nutrient interactions in one-carbon metabolism. Curr Drug Metab 2005;6:37-46.
    • (2005) Curr Drug Metab , vol.6 , pp. 37-46
    • Friso, S.1    Choi, S.W.2
  • 21
    • 84863011800 scopus 로고    scopus 로고
    • Nutritional influences on epigenetics and age-related disease
    • Park LK, Friso S, Choi SW. Nutritional influences on epigenetics and age-related disease. Proc Nutr Soc 2012;71:75-83.
    • (2012) Proc Nutr Soc , vol.71 , pp. 75-83
    • Park, L.K.1    Friso, S.2    Choi, S.W.3
  • 22
    • 0027342248 scopus 로고
    • Major techniques to study DNA methylation
    • Saluz H, Jost JP. Major techniques to study DNA methylation. EXS 1993;64:11-26.
    • (1993) EXS , vol.64 , pp. 11-26
    • Saluz, H.1    Jost, J.P.2
  • 23
    • 0032585866 scopus 로고    scopus 로고
    • DNA methylation analysis: A review of current methodologies
    • Oakeley EJ. DNA methylation analysis: a review of current methodologies. Pharmacol Ther 1999;84:389-400.
    • (1999) Pharmacol Ther , vol.84 , pp. 389-400
    • Oakeley, E.J.1
  • 24
    • 0025031568 scopus 로고
    • Use of a Hpall-polymerase chain reaction assay to study DNA methylation in the Pgk-1 CpG island of mouse embryos at the time of X-chromosome inactivation
    • Singer-Sam J, Grant M, Le Bon JM, Okuyama K, Chapman V, Monk M, et al. Use of a Hpall-polymerase chain reaction assay to study DNA methylation in the Pgk-1 CpG island of mouse embryos at the time of X-chromosome inactivation. Mol Cell Biol 1990;10:4987-9.
    • (1990) Mol Cell Biol , vol.10 , pp. 4987-4989
    • Singer-Sam, J.1    Grant, M.2    Le Bon, J.M.3    Okuyama, K.4    Chapman, V.5    Monk, M.6
  • 25
    • 32644458584 scopus 로고    scopus 로고
    • A reassessment of semiquantitative analytical procedures for DNA methylation: Comparison of bisulfite-and Hpall polymerasechain-reaction-based methods
    • Fuso A, Scarpa S, Grandoni F, Strom R, Lucarelli M. A reassessment of semiquantitative analytical procedures for DNA methylation: comparison of bisulfite-and Hpall polymerasechain-reaction-based methods. Anal Biochem 2006;350:24-31.
    • (2006) Anal Biochem , vol.350 , pp. 24-31
    • Fuso, A.1    Scarpa, S.2    Grandoni, F.3    Strom, R.4    Lucarelli, M.5
  • 26
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong Z, Laird PW. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res 1997;25:2532-4.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 27
    • 16544362680 scopus 로고    scopus 로고
    • Rapid analysis of CpG methylation patterns using RNase T1 cleavage and MALDI-TOF
    • Schatz P, Dietrich D, Schuster M. Rapid analysis of CpG methylation patterns using RNase T1 cleavage and MALDI-TOF. Nucleic Acids Res 2004;32:e167.
    • (2004) Nucleic Acids Res , vol.32
    • Schatz, P.1    Dietrich, D.2    Schuster, M.3
  • 28
    • 34247849498 scopus 로고    scopus 로고
    • Methylation-sensitive high resolution melting (MS-HRM): A new approach for sensitive and high-throughput assessment of methylation
    • Wojdacz TK, Dobrovic A. Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation. Nucleic Acids Res 2007;35:e41.
    • (2007) Nucleic Acids Res , vol.35
    • Wojdacz, T.K.1    Dobrovic, A.2
  • 29
    • 0033785853 scopus 로고    scopus 로고
    • Validation of a multiplex methylationsensitive PCR assay for the diagnosis of Prader-Willi and Angelman's syndromes
    • Buller A, Pandya A, Jackson-Cook C, Bodurtha J, Tekin M, Wilkinson DS, et al. Validation of a multiplex methylationsensitive PCR assay for the diagnosis of Prader-Willi and Angelman's syndromes. Mol Diagn 2000;5:239-43.
    • (2000) Mol Diagn , vol.5 , pp. 239-243
    • Buller, A.1    Pandya, A.2    Jackson-Cook, C.3    Bodurtha, J.4    Tekin, M.5    Wilkinson, D.S.6
  • 31
    • 0027723111 scopus 로고
    • Methylation profiles of genomic DNA of mouse developmental brain detected by restriction landmark genomic scanning (RLGS) method
    • Kawai J, Hirotsune S, Hirose K, Fushiki S, Watanabe S, Hayashizaki Y. Methylation profiles of genomic DNA of mouse developmental brain detected by restriction landmark genomic scanning (RLGS) method. Nucleic Acids Res 1993;21:5604-8.
    • (1993) Nucleic Acids Res , vol.21 , pp. 5604-5608
    • Kawai, J.1    Hirotsune, S.2    Hirose, K.3    Fushiki, S.4    Watanabe, S.5    Hayashizaki, Y.6
  • 33
    • 7044245948 scopus 로고    scopus 로고
    • Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites
    • Sadikovic B, Haines TR, Butcher DT, Rodenhiser DI. Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites. Breast Cancer Res 2004;6:R329-37.
    • (2004) Breast Cancer Res , vol.6
    • Sadikovic, B.1    Haines, T.R.2    Butcher, D.T.3    Rodenhiser, D.I.4
  • 34
    • 12244286046 scopus 로고    scopus 로고
    • Oligonucleotide-based microarray for DNA methylation analysis: Principles and applications
    • Shi H, Maier S, Nimmrich I, Yan PS, Caldwell CW, Olek A, et al. Oligonucleotide-based microarray for DNA methylation analysis: principles and applications. J Cell Biochem 2003;88:138-43.
    • (2003) J Cell Biochem , vol.88 , pp. 138-143
    • Shi, H.1    Maier, S.2    Nimmrich, I.3    Yan, P.S.4    Caldwell, C.W.5    Olek, A.6
  • 35
    • 78049450393 scopus 로고    scopus 로고
    • DNA methylation profiling using the methylated-CpG island recovery assay (MIRA)
    • Rauch TA, Pfeifer GP. DNA methylation profiling using the methylated-CpG island recovery assay (MIRA). Methods 2010;52:213-7.
    • (2010) Methods , vol.52 , pp. 213-217
    • Rauch, T.A.1    Pfeifer, G.P.2
  • 36
    • 78049427089 scopus 로고    scopus 로고
    • Introduction to epigenomics and epigenome-wide analysis
    • Fazzari MJ, Greally JM. Introduction to epigenomics and epigenome-wide analysis. Methods Mol Biol 2010;620:243-65.
    • (2010) Methods Mol Biol , vol.620 , pp. 243-265
    • Fazzari, M.J.1    Greally, J.M.2
  • 38
    • 73249152285 scopus 로고    scopus 로고
    • Immunoprecipitation of methylated DNA
    • Sorensen AL, Collas P. Immunoprecipitation of methylated DNA. Methods Mol Biol 2009;567:249-62.
    • (2009) Methods Mol Biol , vol.567 , pp. 249-262
    • Sorensen, A.L.1    Collas, P.2
  • 39
    • 79251598990 scopus 로고    scopus 로고
    • Comprehensive analysis of DNA-methylation in mammalian tissues using MeDIP-chip
    • Palmke N, Santacruz D, Walter J. Comprehensive analysis of DNA-methylation in mammalian tissues using MeDIP-chip. Methods 2011;53:175-84.
    • (2011) Methods , vol.53 , pp. 175-184
    • Palmke, N.1    Santacruz, D.2    Walter, J.3
  • 42
    • 78149433116 scopus 로고    scopus 로고
    • Role of epigenetics in Alzheimer's and Parkinson's disease
    • Kwok JB. Role of epigenetics in Alzheimer's and Parkinson's disease. Epigenomics 2010;2:671-82.
    • (2010) Epigenomics , vol.2 , pp. 671-682
    • Kwok, J.B.1
  • 44
    • 77958491286 scopus 로고    scopus 로고
    • Summary and discussion: Methodologies to assess long-term effects of nutrition on brain function
    • De Jager CA, Kovatcheva A. Summary and discussion: methodologies to assess long-term effects of nutrition on brain function. Nutr Rev 2010;68:S53-8.
    • (2010) Nutr Rev , vol.68
    • De Jager, C.A.1    Kovatcheva, A.2
  • 45
    • 79955675256 scopus 로고    scopus 로고
    • Diet induced epigenetic changes and their implications for health
    • McKay JA, Mathers JC. Diet induced epigenetic changes and their implications for health. Acta Physiol 2011;202:103-18.
    • (2011) Acta Physiol , vol.202 , pp. 103-118
    • McKay, J.A.1    Mathers, J.C.2
  • 46
    • 79951768624 scopus 로고    scopus 로고
    • Epigenetics and maternal nutrition: Nature v. nurture
    • Simmons R. Epigenetics and maternal nutrition: nature v. nurture. Proc Nutr Soc 2011;70:73-81.
    • (2011) Proc Nutr Soc , vol.70 , pp. 73-81
    • Simmons, R.1
  • 47
    • 79958766232 scopus 로고    scopus 로고
    • One-carbon metabolism and Alzheimer's disease: Is it all a methylation matter?
    • Fuso A, Scarpa S. One-carbon metabolism and Alzheimer's disease: is it all a methylation matter? Neurobiol Aging 2011;32:1192-5.
    • (2011) Neurobiol Aging , vol.32 , pp. 1192-1195
    • Fuso, A.1    Scarpa, S.2
  • 48
    • 84865587194 scopus 로고    scopus 로고
    • Environmental triggers and epigenetic deregulation in autoimmune disease
    • Javierre BM, Hernando H, Ballestar E. Environmental triggers and epigenetic deregulation in autoimmune disease. Discov Med 2011;12:535-45.
    • (2011) Discov Med , vol.12 , pp. 535-545
    • Javierre, B.M.1    Hernando, H.2    Ballestar, E.3
  • 49
    • 84862794288 scopus 로고    scopus 로고
    • Epigenetics, asthma, and allergic diseases: A review of the latest advancements
    • Lovinsky-Desir S, Miller RL. Epigenetics, asthma, and allergic diseases: a review of the latest advancements. Curr Allergy Asthma Rep 2012;12:211-20.
    • (2012) Curr Allergy Asthma Rep , vol.12 , pp. 211-220
    • Lovinsky-Desir, S.1    Miller, R.L.2
  • 50
    • 0037136537 scopus 로고    scopus 로고
    • The effect of infections on susceptibility to autoimmune and allergic diseases
    • Bach JF. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med 2002;347:911-20.
    • (2002) N Engl J Med , vol.347 , pp. 911-920
    • Bach, J.F.1
  • 53
    • 77956642106 scopus 로고    scopus 로고
    • Variation, patterns, and temporal stability of DNA methylation: Considerations for epigenetic epidemiology
    • Talens RP, Boomsma DI, Tobi EW, Kremer D, Jukema JW, Willemsen G, et al. Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology. FASEBJ 2010;24:3135-44.
    • (2010) FASEBJ , vol.24 , pp. 3135-3144
    • Talens, R.P.1    Boomsma, D.I.2    Tobi, E.W.3    Kremer, D.4    Jukema, J.W.5    Willemsen, G.6
  • 54
    • 73249133400 scopus 로고    scopus 로고
    • Epigenetics: A molecular link between environmental factors and type 2 diabetes
    • Ling C, Groop L. Epigenetics: a molecular link between environmental factors and type 2 diabetes. Diabetes 2009;58:2718-25.
    • (2009) Diabetes , vol.58 , pp. 2718-2725
    • Ling, C.1    Groop, L.2
  • 56
    • 36348971786 scopus 로고    scopus 로고
    • Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene
    • Jamaluddin MD, Chen I, Yang F, Jiang X, Jan M, Liu X, et al. Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. Blood 2007;110:3648-55.
    • (2007) Blood , vol.110 , pp. 3648-3655
    • Jamaluddin, M.D.1    Chen, I.2    Yang, F.3    Jiang, X.4    Jan, M.5    Liu, X.6
  • 57
    • 70450251955 scopus 로고    scopus 로고
    • DNA methyltransferase inhibition induces mouse embryonic stem cell differentiation into endothelial cells
    • Banerjee S, Bacanamwo M. DNA methyltransferase inhibition induces mouse embryonic stem cell differentiation into endothelial cells. Exp Cell Res 2010;316:172-80.
    • (2010) Exp Cell Res , vol.316 , pp. 172-180
    • Banerjee, S.1    Bacanamwo, M.2
  • 58
    • 84857842836 scopus 로고    scopus 로고
    • Epigenetics: A tool to understand diet-related cardiovascular risk?
    • Zaina S, Lund G. Epigenetics: a tool to understand diet-related cardiovascular risk? J Nutrigenet Nutrigenomics 2011;4:261-74.
    • (2011) J Nutrigenet Nutrigenomics , vol.4 , pp. 261-274
    • Zaina, S.1    Lund, G.2
  • 59
    • 36549037764 scopus 로고    scopus 로고
    • Shared epigenetic mechanisms control virulence factors in protozoan parasites
    • Lopez-Rubio JJ, Riviere L, Scherf A. Shared epigenetic mechanisms control virulence factors in protozoan parasites. Curr Opin Microbiol 2007;10:560-8.
    • (2007) Curr Opin Microbiol , vol.10 , pp. 560-568
    • Lopez-Rubio, J.J.1    Riviere, L.2    Scherf, A.3
  • 60
    • 63449109908 scopus 로고    scopus 로고
    • Microbe-induced epigenetic alterations in host cells: The coming era of patho-epigenetics of microbial infections. A review
    • Minarovits J. Microbe-induced epigenetic alterations in host cells: the coming era of patho-epigenetics of microbial infections. A review. Acta Microbiol Immunol Hung 2009;56:1-19.
    • (2009) Acta Microbiol Immunol Hung , vol.56 , pp. 1-19
    • Minarovits, J.1
  • 61
    • 84856200093 scopus 로고    scopus 로고
    • Towards unveiling the genetics of neurodegenerative diseases
    • Lill CM, Bertram L. Towards unveiling the genetics of neurodegenerative diseases. Semin Neurol 2011;31:531-41.
    • (2011) Semin Neurol , vol.31 , pp. 531-541
    • Lill, C.M.1    Bertram, L.2
  • 62
    • 67649185049 scopus 로고    scopus 로고
    • Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases
    • Migliore L, Coppede F. Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases. Mutat Res 2009;667:82-97.
    • (2009) Mutat Res , vol.667 , pp. 82-97
    • Migliore, L.1    Coppede, F.2
  • 64
  • 66
    • 33646747001 scopus 로고    scopus 로고
    • Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia
    • Obeid R, Herrmann W. Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia. FEBS Lett 2006;580:2994-3005.
    • (2006) FEBS Lett , vol.580 , pp. 2994-3005
    • Obeid, R.1    Herrmann, W.2
  • 67
    • 70350432817 scopus 로고    scopus 로고
    • The LEARn model: An epigenetic explanation for idiopathic neurobiological diseases
    • Lahiri DK, Maloney B, Zawia NH. The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases. Mol Psychiatry 2009;14:992-1003.
    • (2009) Mol Psychiatry , vol.14 , pp. 992-1003
    • Lahiri, D.K.1    Maloney, B.2    Zawia, N.H.3
  • 68
    • 70349798896 scopus 로고    scopus 로고
    • The epigenetic bottleneck of neurodegenerative and psychiatric diseases
    • Sananbenesi F, Fischer A. The epigenetic bottleneck of neurodegenerative and psychiatric diseases. Biol Chem 2009;390:1145-53.
    • (2009) Biol Chem , vol.390 , pp. 1145-1153
    • Sananbenesi, F.1    Fischer, A.2
  • 70
    • 79957623760 scopus 로고    scopus 로고
    • Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss
    • Klein CJ, Botuyan MV, Wu Y, Ward CJ, Nicholson GA, Hammans S, et al. Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. Nat Genet 2011;43:595-600.
    • (2011) Nat Genet , vol.43 , pp. 595-600
    • Klein, C.J.1    Botuyan, M.V.2    Wu, Y.3    Ward, C.J.4    Nicholson, G.A.5    Hammans, S.6
  • 71
    • 84860491605 scopus 로고    scopus 로고
    • Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy
    • Winkelmann J, Lin L, Schormair B, Kornum BR, Faraco J, Plazzi G, et al. Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy. Hum Mol Genet 2012;21:2205-10.
    • (2012) Hum Mol Genet , vol.21 , pp. 2205-2210
    • Winkelmann, J.1    Lin, L.2    Schormair, B.3    Kornum, B.R.4    Faraco, J.5    Plazzi, G.6
  • 74
    • 84878113388 scopus 로고    scopus 로고
    • Epigenetic mechanisms governing the process of neurodegeneration
    • Jul. 7. DOI
    • Qureshi IA, Mehler MF. Epigenetic mechanisms governing the process of neurodegeneration. Mol Aspects Med 2012 Jul. 7. DOI: http://dx.doi.org/10. 10167j.mam.2012.06.011.
    • (2012) Mol Aspects Med
    • Qureshi, I.A.1    Mehler, M.F.2
  • 76
    • 84860843024 scopus 로고    scopus 로고
    • Epigenetics DNA methylation in the core ataxin-2 gene promoter: Novel physiological and pathological implications
    • Laffita-Mesa JM, Bauer PO, Kourf V, Pena Serrano L, Roskams J, Almaguer Gotay D, et al. Epigenetics DNA methylation in the core ataxin-2 gene promoter: novel physiological and pathological implications. Hum Genet 2012;131:625-38.
    • (2012) Hum Genet , vol.131 , pp. 625-638
    • Laffita-Mesa, J.M.1    Bauer, P.O.2    Kourf, V.3    Pena Serrano, L.4    Roskams, J.5    Almaguer Gotay, D.6
  • 77
    • 80054787664 scopus 로고    scopus 로고
    • What genetics tells us about the causes and mechanisms of Parkinson's disease
    • Corti O, Lesage S, Brice A. What genetics tells us about the causes and mechanisms of Parkinson's disease. Physiol Rev 2011;91:1161-218.
    • (2011) Physiol Rev , vol.91 , pp. 1161-1218
    • Corti, O.1    Lesage, S.2    Brice, A.3
  • 78
    • 77951842993 scopus 로고    scopus 로고
    • Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains
    • Jowaed A, Schmitt I, Kaut O, Wullner U. Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains. J Neurosci 2010;30:6355-9.
    • (2010) J Neurosci , vol.30 , pp. 6355-6359
    • Jowaed, A.1    Schmitt, I.2    Kaut, O.3    Wullner, U.4
  • 79
    • 78649652766 scopus 로고    scopus 로고
    • CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease
    • Matsumoto L, Takuma H, Tamaoka A, Kurisaki H, Date H, Tsuji S, et al. CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease. PLoS One 2010;5:e15522.
    • (2010) PLoS One , vol.5
    • Matsumoto, L.1    Takuma, H.2    Tamaoka, A.3    Kurisaki, H.4    Date, H.5    Tsuji, S.6
  • 80
    • 79959851714 scopus 로고    scopus 로고
    • International Parkinson's Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2). A two-stage meta-analysis identifies several new loci for Parkinson's disease
    • International Parkinson's Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2). A two-stage meta-analysis identifies several new loci for Parkinson's disease. PLoS Genet 2011;7:e1002142.
    • (2011) PLoS Genet , vol.7
  • 82
    • 41149090082 scopus 로고    scopus 로고
    • DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons
    • Siegmund KD, Connor CM, Campan M, Long TI, Weisenberger DJ, Biniszkiewicz D, et al. DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PLoS ONE 2007;2:e895.
    • (2007) PLoS ONE , vol.2
    • Siegmund, K.D.1    Connor, C.M.2    Campan, M.3    Long, T.I.4    Weisenberger, D.J.5    Biniszkiewicz, D.6
  • 83
    • 49949108971 scopus 로고    scopus 로고
    • Age-specific epigenetic drift in late-onset Alzheimer's disease
    • Wang SC, Oelze B, Schumacher A. Age-specific epigenetic drift in late-onset Alzheimer's disease. PLoS ONE 2008;3:e2698.
    • (2008) PLoS ONE , vol.3
    • Wang, S.C.1    Oelze, B.2    Schumacher, A.3
  • 84
    • 84859412462 scopus 로고    scopus 로고
    • Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex
    • Bakulski KM, Dolinoy DC, Sartor MA, Paulson HL, Konen JR, Lieberman AP, et al. Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex. J Alzheimers Dis 2012;29:571-88.
    • (2012) J Alzheimers Dis , vol.29 , pp. 571-588
    • Bakulski, K.M.1    Dolinoy, D.C.2    Sartor, M.A.3    Paulson, H.L.4    Konen, J.R.5    Lieberman, A.P.6
  • 85
    • 84860368886 scopus 로고    scopus 로고
    • S-adenosylmethionine reduces the progress of the Alzheimerlike features induced by B-vitamin deficiency in mice
    • Fuso A, Nicolia V, Ricceri L, Cavallaro RA, Isopi E, Mangia F, et al. S-adenosylmethionine reduces the progress of the Alzheimerlike features induced by B-vitamin deficiency in mice. Neurobiol Aging 2012;33:1482. e1-16.
    • (2012) Neurobiol Aging , vol.33
    • Fuso, A.1    Nicolia, V.2    Ricceri, L.3    Cavallaro, R.A.4    Isopi, E.5    Mangia, F.6
  • 86
    • 77149130504 scopus 로고    scopus 로고
    • B vitamin deficiency promotes tau phosphorylation through regulation of GSK3beta and PP2A
    • Nicolia V, Fuso A, Cavallaro RA, Di Luzio A, Scarpa S. B vitamin deficiency promotes tau phosphorylation through regulation of GSK3beta and PP2A. J Alzheimers Dis 2010;19:895-907.
    • (2010) J Alzheimers Dis , vol.19 , pp. 895-907
    • Nicolia, V.1    Fuso, A.2    Cavallaro, R.A.3    Di Luzio, A.4    Scarpa, S.5
  • 88
    • 80555122780 scopus 로고    scopus 로고
    • Amyloid proteinmediated differential DNA methylation status regulates gene expression in Alzheimer's disease model cell line
    • Sung HY, Choi EN, Ahn Jo S, Oh S, Ahn JH. Amyloid proteinmediated differential DNA methylation status regulates gene expression in Alzheimer's disease model cell line. Biochem Biophys Res Commun 2011;414:700-5.
    • (2011) Biochem Biophys Res Commun , vol.414 , pp. 700-705
    • Sung, H.Y.1    Choi, E.N.2    Ahn Jo, S.3    Oh, S.4    Ahn, J.H.5
  • 89
    • 84869223239 scopus 로고    scopus 로고
    • The APP family members are key players in S-adenosylmethionine formation by MAT2A and modify BACE1 and PSEN1 gene expression - Relevance for Alzheimer's disease
    • Aug. 9. DOI: 10.1074/mcp. M112.019364 mcp. M112.019364
    • Schrotter A, Pfeiffer K, El Magraoui F, Platta H, Erdmann R, Meyer HE, et al. The APP family members are key players in S-adenosylmethionine formation by MAT2A and modify BACE1 and PSEN1 gene expression - relevance for Alzheimer's disease. Mol Cell Proteomics 2012 Aug. 9. DOI: 10.1074/mcp. M112.019364 mcp. M112.019364.
    • (2012) Mol Cell Proteomics
    • Schrotter, A.1    Pfeiffer, K.2    El Magraoui, F.3    Platta, H.4    Erdmann, R.5    Meyer, H.E.6
  • 90
    • 82255192294 scopus 로고    scopus 로고
    • 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging
    • Szulwach KE, Li X, Li Y, Song CX, Wu H, Dai Q, et al. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci 2011;14:1607-16.
    • (2011) Nat Neurosci , vol.14 , pp. 1607-1616
    • Szulwach, K.E.1    Li, X.2    Li, Y.3    Song, C.X.4    Wu, H.5    Dai, Q.6
  • 91
    • 84861123503 scopus 로고    scopus 로고
    • Applying epigenetics to Alzheimer's disease via the latent early-life associated regulation (LEARn) model
    • Maloney B, Sambamurti K, Zawia N, Lahiri DK. Applying epigenetics to Alzheimer's disease via the latent early-life associated regulation (LEARn) model. Curr Alzheimer Res 2012;9:589-99.
    • (2012) Curr Alzheimer Res , vol.9 , pp. 589-599
    • Maloney, B.1    Sambamurti, K.2    Zawia, N.3    Lahiri, D.K.4
  • 93
    • 68949096744 scopus 로고    scopus 로고
    • Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease
    • Mastroeni D, McKee A, Grover A, Rogers J, Coleman PD. Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease. PLoS One 2009;4:e6617.
    • (2009) PLoS One , vol.4
    • Mastroeni, D.1    McKee, A.2    Grover, A.3    Rogers, J.4    Coleman, P.D.5
  • 94
    • 84858294466 scopus 로고    scopus 로고
    • What monozygotic twins discordant for phenotype illustrate about mechanisms influencing genetic forms of neurodegeneration
    • Ketelaar ME, Hofstra EM, Hayden MR. What monozygotic twins discordant for phenotype illustrate about mechanisms influencing genetic forms of neurodegeneration. Clin Genet 2012;81:325-33.
    • (2012) Clin Genet , vol.81 , pp. 325-333
    • Ketelaar, M.E.1    Hofstra, E.M.2    Hayden, M.R.3
  • 95


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.