The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study

BMC Cancer

Volumn 12, Issue , 2012, Pages

  Rutkowski, Piotr ^a   Bylina, Elzbieta ^a   Klimczak, Anna ^a   Świtaj, Tomasz ^a   Falkowski, Sławomir ^a   Kroc, Jacek ^b   Ługowska, Iwona ^a   Brzeskwiniewicz, Magdalena ^c   Melerowicz, Wojciech ^d   Osuch, Czesław ^e   Mierzejewska, Ewa ^f   Wasielewski, Kacper ^c   Woźniak, Agnieszka ^g   Grzesiakowska, Urszula ^a   Nowecki, Zbigniew I ^a   Siedlecki, Janusz A ^a   Limon, Janusz ^c  

^a INSTITUTE OF ONCOLOGY   (Poland)

^b Pfizer Poland   (Poland)

^c MEDICAL UNIVERSITY OF GDANSK   (Poland)

^d GreaterPoland Oncological Center   (Poland)

^e JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^f INSTITUTE OF MOTHER AND CHILD   (Poland)

^g UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Arterial hypertension; Genotype; GIST; Predictive factors; Prognosis; Sunitinib

Indexed keywords

IMATINIB; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; STEM CELL FACTOR RECEPTOR; SUNITINIB; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; VEGFA PROTEIN, HUMAN;

ADOLESCENT; ADULT; ADVANCED CANCER; AGED; ALLELE; ANEMIA; ANOREXIA; ARTICLE; BLEEDING; BLOOD TOXICITY; CARCINOGENESIS; CLINICAL STUDY; CONTINUOUS INFUSION; CONTROLLED STUDY; DIARRHEA; DRUG DOSE REDUCTION; DRUG FATALITY; DYSGEUSIA; DYSPEPSIA; EXON; FATIGUE; FEMALE; FOLLOW UP; GASTROINTESTINAL STROMAL TUMOR; GENE; GENETIC VARIABILITY; GENOTYPE; HAIR DISCOLORATION; HAND FOOT SYNDROME; HIGH RISK PATIENT; HUMAN; HYPERTENSION; HYPOTHYROIDISM; INTESTINE PERFORATION; KIT GENE; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; MUTATIONAL ANALYSIS; NEUTROPENIA; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PDGFRA GENE; PREDICTION; PROGRESSION FREE SURVIVAL; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN DISCOLORATION; THROMBOCYTOPENIA; TREATMENT DURATION; TREATMENT FAILURE; TUMOR PERFORATION; VEGFA GENE; VEGFR2 GENE; DISEASE FREE SURVIVAL; GASTROINTESTINAL TUMOR; GENETICS; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOLOGY; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; DISEASE-FREE SURVIVAL; FEMALE; GASTROINTESTINAL NEOPLASMS; GASTROINTESTINAL STROMAL TUMORS; HUMANS; INDOLES; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PIPERAZINES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN KINASE INHIBITORS; PYRIMIDINES; PYRROLES; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; YOUNG ADULT;

EID: 84858713323     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-12-107     Document Type: Article

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