-
1
-
-
0028169741
-
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain
-
Kaplitt MG et al. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat Genet 1994; 8: 148-154.
-
(1994)
Nat. Genet.
, vol.8
, pp. 148-154
-
-
Kaplitt, M.G.1
-
2
-
-
0030003480
-
Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector
-
McCown TJ et al. Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector. Brain Res 1996; 713: 99-107.
-
(1996)
Brain Res.
, vol.713
, pp. 99-107
-
-
McCown, T.J.1
-
3
-
-
0033585514
-
Adeno-associated virus-mediated gene transfer to the brain: Duration and modulation of expression
-
Lo WD et al. Adeno-associated virus-mediated gene transfer to the brain: duration and modulation of expression. Hum Gene Ther 1999; 10: 201-213.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 201-213
-
-
Lo, W.D.1
-
4
-
-
0033389722
-
Gene transfer into the CNS using recombinant adeno-associated virus: Analysis of vector DNA forms resulting in sustained expression
-
Clark KR et al. Gene transfer into the CNS using recombinant adeno-associated virus: analysis of vector DNA forms resulting in sustained expression. J Drug Target 1999; 7: 269-283.
-
(1999)
J. Drug Target.
, vol.7
, pp. 269-283
-
-
Clark, K.R.1
-
5
-
-
0031456051
-
Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats
-
Mandel RJ et al. Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats. Proc Natl Acad Sci USA 1997; 94: 14083-14088.
-
(1997)
Proc. Natl. Acad Sci. USA
, vol.94
, pp. 14083-14088
-
-
Mandel, R.J.1
-
6
-
-
0032553713
-
Behavioral recovery in 6-hydroxydompamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors
-
Fan DS et al. Behavioral recovery in 6-hydroxydompamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors. Hum Gene Ther 1998; 9: 2527-2535.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 2527-2535
-
-
Fan, D.S.1
-
7
-
-
0032758906
-
Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice
-
Skorupa AF et al. Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice. Exp Neurol 1999; 160: 17-27.
-
(1999)
Exp. Neurol.
, vol.160
, pp. 17-27
-
-
Skorupa, A.F.1
-
8
-
-
0032918107
-
Long-term actions of vector-derived nerve growth factor or brain-derived neurotrophic factor on choline acetyltransferase and Trk receptor levels in the adult rat basal forebrain
-
Klein RL et al. Long-term actions of vector-derived nerve growth factor or brain-derived neurotrophic factor on choline acetyltransferase and Trk receptor levels in the adult rat basal forebrain. Neuroscience 1999; 90: 815-821.
-
(1999)
Neuroscience
, vol.90
, pp. 815-821
-
-
Klein, R.L.1
-
9
-
-
0034088881
-
Recombinant adeno-associated virus-mediated correction of lysosomal storage within the central nervous system of the adult mucopolysaccharidosis type VII mouse
-
Sferra TJ et al. Recombinant adeno-associated virus-mediated correction of lysosomal storage within the central nervous system of the adult mucopolysaccharidosis type VII mouse. Hum Gene Ther 2000; 11: 507-519.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 507-519
-
-
Sferra, T.J.1
-
10
-
-
0034980351
-
Combined injection of rAAV with mannitol enhances gene expression in the rat brain
-
Mastakov MY et al. Combined injection of rAAV with mannitol enhances gene expression in the rat brain. Mol Ther 2001; 3: 225-232.
-
(2001)
Mol. Ther.
, vol.3
, pp. 225-232
-
-
Mastakov, M.Y.1
-
11
-
-
0031875751
-
In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector
-
During MJ et al. In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector. Gene Ther 1998; 5: 820-827.
-
(1998)
Gene Ther.
, vol.5
, pp. 820-827
-
-
During, M.J.1
-
12
-
-
0032550793
-
Selective and rapid uptake of adeno-associated virus type 2 in brain
-
Bartlett JS, Samulski RJ, McCown TJ. Selective and rapid uptake of adeno-associated virus type 2 in brain. Hum Gene Ther 1998; 9: 1181-1186.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 1181-1186
-
-
Bartlett, J.S.1
Samulski, R.J.2
McCown, T.J.3
-
13
-
-
0035120218
-
Heparin coinfusion during convection-enhanced delivery (CED) increases the distribution of the glial-derived neurotrophic factor (GDNF) ligand family in rat striatum and enhances the pharmacological activity of neurturin
-
Hamilton JF et al. Heparin coinfusion during convection-enhanced delivery (CED) increases the distribution of the glial-derived neurotrophic factor (GDNF) ligand family in rat striatum and enhances the pharmacological activity of neurturin. Exp Neurol 2001; 168: 155-161.
-
(2001)
Exp. Neurol.
, vol.168
, pp. 155-161
-
-
Hamilton, J.F.1
-
14
-
-
0035800208
-
Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain
-
Nguyen JB et al. Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain. Neuroreport 2001; 12: 1961-1964.
-
(2001)
Neuroreport.
, vol.12
, pp. 1961-1964
-
-
Nguyen, J.B.1
-
15
-
-
0036315299
-
Immunological aspects of recombinant adeno-associated virus delivery to the mammalian brain
-
Mastakov MY et al. Immunological aspects of recombinant adeno-associated virus delivery to the mammalian brain. J Virol 2002; 76: 8446-8454.
-
(2002)
J. Virol.
, vol.76
, pp. 8446-8454
-
-
Mastakov, M.Y.1
-
16
-
-
0032870158
-
Genetic capsid modifications allow efficient re-targeting of adeno- Associated virus type 2
-
Girod A et al. Genetic capsid modifications allow efficient re-targeting of adeno- associated virus type 2. Nat Med 1999; 5: 1052-1056.
-
(1999)
Nat. Med.
, vol.5
, pp. 1052-1056
-
-
Girod, A.1
-
17
-
-
0033851104
-
Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism
-
Wu P et al. Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism. J Virol 2000; 74: 8635-8647.
-
(2000)
J. Virol.
, vol.74
, pp. 8635-8647
-
-
Wu, P.1
-
18
-
-
0034814413
-
Insertional mutagenesis of the adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors targeted to alternative cell- surface receptors
-
Shi W, Arnold GS, Bartlett JS. Insertional mutagenesis of the adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors targeted to alternative cell- surface receptors. Hum Gene Ther 2001; 12: 1697-1711.
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 1697-1711
-
-
Shi, W.1
Arnold, G.S.2
Bartlett, J.S.3
-
19
-
-
0033007934
-
Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody
-
Bartlett JS et al. Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody. Nat Biotechnol 1999; 17: 181-186.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 181-186
-
-
Bartlett, J.S.1
-
20
-
-
0030841312
-
Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles
-
Chiorini JA et al. Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles. J Virol 1997; 71: 6823-6833.
-
(1997)
J. Virol.
, vol.71
, pp. 6823-6833
-
-
Chiorini, J.A.1
-
21
-
-
0031984786
-
Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2
-
Rutledge EA, Halbert CL, Russell DW. Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2. J Virol 1998; 72: 309-319.
-
(1998)
J. Virol.
, vol.72
, pp. 309-319
-
-
Rutledge, E.A.1
Halbert, C.L.2
Russell, D.W.3
-
22
-
-
0032959311
-
Cloning and characterization of adeno-associated virus type 5
-
Chiorini JA et al. Cloning and characterization of adeno-associated virus type 5. J Virol 1999; 73: 1309-1319.
-
(1999)
J. Virol.
, vol.73
, pp. 1309-1319
-
-
Chiorini, J.A.1
-
23
-
-
0032924185
-
Gene therapy vectors based on adeno-associated virus type 1
-
Xiao W et al. Gene therapy vectors based on adeno-associated virus type 1. J Virol 1999; 73: 3994-4003.
-
(1999)
J. Virol.
, vol.73
, pp. 3994-4003
-
-
Xiao, W.1
-
24
-
-
0036140216
-
Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity
-
Rabinowitz JE et al. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity. J Virol 2002; 76: 791-801.
-
(2002)
J. Virol.
, vol.76
, pp. 791-801
-
-
Rabinowitz, J.E.1
-
25
-
-
0037015049
-
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
-
Gao G-P et al. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proc Natl Acad Sci USA 2002; 99: 11854-11859.
-
(2002)
Proc. Natl. Acad Sci. USA
, vol.99
, pp. 11854-11859
-
-
Gao, G.-P.1
-
26
-
-
0034572459
-
Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors
-
Chao H et al. Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors. Mol Ther 2000; 2: 619-623.
-
(2000)
Mol. Ther.
, vol.2
, pp. 619-623
-
-
Chao, H.1
-
27
-
-
0034724209
-
Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system
-
Davidson BL et al. Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system. Proc Natl Acad Sci USA 2000; 97: 3428-3432.
-
(2000)
Proc. Natl. Acad Sci. USA
, vol.97
, pp. 3428-3432
-
-
Davidson, B.L.1
-
28
-
-
0035894739
-
Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: The retina as a model
-
Auricchio A et al. Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model. Hum Mol Genet 2001; 10: 3075-3081.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 3075-3081
-
-
Auricchio, A.1
-
29
-
-
0031906147
-
Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions
-
Summerford C, Samulski RJ. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J Virol 1998; 72: 1438-1445.
-
(1998)
J. Virol.
, vol.72
, pp. 1438-1445
-
-
Summerford, C.1
Samulski, R.J.2
-
30
-
-
0034957168
-
Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity
-
Kaludov N et al. Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity. J Virol 2001; 75: 6884-6893.
-
(2001)
J. Virol.
, vol.75
, pp. 6884-6893
-
-
Kaludov, N.1
-
31
-
-
0035827546
-
Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer
-
Walters RW et al. Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer. J Biol Chem 2001; 276: 20610-20616.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20610-20616
-
-
Walters, R.W.1
-
32
-
-
0033541640
-
Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses
-
Clark KR et al. Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses. Hum Gene Ther 1999; 10: 1031-1039.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 1031-1039
-
-
Clark, K.R.1
-
33
-
-
0032051603
-
Neuron-specific transduction in the rat sep-tohippocampal or nigrostriatal pathway by recombinat adeno-associated virus vectors
-
Klein RL et al. Neuron-specific transduction in the rat sep-tohippocampal or nigrostriatal pathway by recombinat adeno-associated virus vectors. Exp Neurol 1998; 150: 183-194.
-
(1998)
Exp. Neurol.
, vol.150
, pp. 183-194
-
-
Klein, R.L.1
-
34
-
-
0036703479
-
Distribution of a lysosomal enzyme in the adult brain by axonal transport and by cells of the rostral migratory stream
-
Passini MA et al. Distribution of a lysosomal enzyme in the adult brain by axonal transport and by cells of the rostral migratory stream. J Neurosci 2002; 22: 6437-6446.
-
(2002)
J. Neurosci.
, vol.22
, pp. 6437-6446
-
-
Passini, M.A.1
-
35
-
-
0036096542
-
Identification of neural stem cells in the adult vertebrate brain
-
Alvarez-Buylla A, Seri B, Doetsch F. Identification of neural stem cells in the adult vertebrate brain. Brain Res Bull 2002; 57: 751-758.
-
(2002)
Brain Res. Bull.
, vol.57
, pp. 751-758
-
-
Alvarez-Buylla, A.1
Seri, B.2
Doetsch, F.3
-
36
-
-
0033557611
-
Oligodendrocyte-specific gene expression in mouse brain: Use of a myelin-forming cell type-specific promoter in an adeno-associated virus
-
Chen H et al. Oligodendrocyte-specific gene expression in mouse brain: use of a myelin-forming cell type-specific promoter in an adeno-associated virus. J Neurosci Res 1999; 55: 504-513.
-
(1999)
J. Neurosci. Res.
, vol.55
, pp. 504-513
-
-
Chen, H.1
-
37
-
-
0028889443
-
Cell lines for the production of recombinant adeno-associated virus
-
Clark KR et al. Cell lines for the production of recombinant adeno-associated virus. Hum Gene Ther 1995; 6: 1329-1341.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 1329-1341
-
-
Clark, K.R.1
-
38
-
-
0023216839
-
A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication
-
Samulski RJ, Chang L-S, Shenk T. A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. J Virol 1987; 61: 3097-3101.
-
(1987)
J. Virol.
, vol.61
, pp. 3097-3101
-
-
Samulski, R.J.1
Chang, L.-S.2
Shenk, T.3
-
39
-
-
0033022953
-
Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield
-
Zolotukhin S et al. Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield. Gene Therapy 1999; 6: 973-985.
-
(1999)
Gene Therapy
, vol.6
, pp. 973-985
-
-
Zolotukhin, S.1
|