Early upregulation of NLRP3 in the brain of neonatal mice exposed to hypoxia-ischemia: No early neuroprotective effects of NLRP3 deficiency

Neonatology

Volumn 108, Issue 3, 2015, Pages 211-219

  Ystgaard, Martin Bogale ^a   Sejersted, Yngve ^a   Løberg, Else Marit ^b   Lien, Egil ^d,e   Yndestad, Arne ^b,c   Saugstad, Ola Didrik ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

^d NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Hypoxia ischemia; Neonatal brain; NLRP3 inflammasome

Indexed keywords

CRYOPYRIN; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; MESSENGER RNA; TRIPHENYLTETRAZOLIUM; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; IL1B PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD LEVEL; BRAIN DAMAGE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN REGION; CAROTID ARTERY LIGATION; CONTROLLED STUDY; CORPUS STRIATUM; DENTATE GYRUS; ENZYME LINKED IMMUNOSORBENT ASSAY; HABENULA; HEMISPHERE; HIPPOCAMPUS; HISTOPATHOLOGY; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IMMUNOHISTOCHEMISTRY; MICROGLIA; MOUSE; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; THALAMUS; UPREGULATION; ANIMAL; BLOOD; BRAIN; C57BL MOUSE; GENETICS; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BRAIN; CARRIER PROTEINS; HYPOXIA-ISCHEMIA, BRAIN; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-18; INTERLEUKIN-1BETA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; UP-REGULATION;

EID: 84939516010     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000437247     Document Type: Article

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