Enhanced expression of interleukin (IL)-1 and IL-6 messenger RNA and bioactive protein after hypoxia-ischemia in neonatal rats

Pediatric Research

Volumn 40, Issue 4, 1996, Pages 603-609

  Hagberg, H ^a,c   Gilland, E ^a   Bona, E ^a   Hanson, L A ^a   Hahn Zoric, M ^a   Blennow, M ^b   Holst, M ^b   McRae, A ^a   Soder O ^b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; POLYADENYLATED RNA; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOREGULATION; NEWBORN; NEWBORN DISEASE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0029762336     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199610000-00015     Document Type: Article

References (48)

1. Clark WM, Madden KP, Rothlein R, Zivin JA 1991 Reduction of central nervous system ischemic injury in rabbits using leukocyte adhesion antibody treatment. Stroke 22:877-883
2. Jiang N, Zhang R-L, Chen H, Chopp M 1994 Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient (2 h) but not after permanent MCA occlusion in the rat brain. Neurosci Res Commun 15:85-93
3. Giulian D, Robertson C 1990 Inhibition of mononuclear phagocytes reduces ischemic injury in the spinal cord. Ann Neurol 27:33-42
4. Rothwell NJ, Relton JK 1993 Involvement of interleukin-1 and lipocortin-1 in ischaemic brain damage. Cerebrovasc Brain Metab Rev 5:178-198
5. Yabuuchi K, Minami M, Katsumata S, Satoh M 1994 Localization of type I interleukin-1 receptor mRNA in the rat brain. Mol Brain Res 27:27-36
6. Liu T, McDonnell PC, Young PR, White RF, Siren AL, Hallenback JM, Barone FC, Feuerstein GZ 1993 Interleukin-1β mRNA expression in ischemic rat cortex. Stroke 24:1746-1750
7. Buttini M, Sauter A, Boddeke HWGM 1994 Induction of interleukin-1β mRNA after focal cerebral ischaemia in the rat. Mol Brain Res 23:126-134
8. Tarkowski E, Rosengren L, Blomstrand C, Wikkelsö C, Jensen C, Ekholm S, Tarkowski A 1995 Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke. Stroke 26:1393-1398
9. Fassbender K, Rossol S, Kammer T, Daffertshofer M, Wirth S, Dollman M, Hennerici M 1994 Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease. J Neurol Sci 122:135-139
10. Relton JK, Rothwell NJ 1992 Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat. Brain Res Bull 29:243-246
11. Betz AL, Yang G-Y, Davidson BL 1995 Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. J Cereb Blood Flow Metab 15:547-551
12. Pillay V, Savage N, Laburn H 1993 Interleukin-1 receptor antagonist in newborn babies and pregnant women. Pflugers Arch 424:549-551
13. lck modulation in CD3- or CD2-activated T cells from neonates. Pediatr Res 37:64-69
14. Leviton A 1993 Preterm birth and cerebral palsy: is tumor necrosis factor the missing link? Dev Med Child Neurol 35:549-558
15. Szaflarski J, Burtrum D, Silverstein FS 1995 Cerebral hypoxia-ischemia stimulates cytokine gene expression in the perinatal rats. Stroke 26:1-8
16. Martin D, Chinookoswong N, Miller G 1994 The interleukin-1 receptor antagonist (rhIL-1ra) protects against cerebral infarction in a rat model of hypoxia-ischemia. Exp Neurol 130:362-367
17. Dinarello CA 1994 Interleukin-1. In: Thomson AW (ed) The Cytokine Handbook. Academic Press, Boston, pp 31-57
18. Dwyer BE, Nishimura RN, Powell CL, Mailheau SL 1987 Focal protein synthesis inhibition in a model of neonatal hypoxic-ischemic brain injury. Exp Neurol 95:277-289
19. Li Y, Chopp M, Zhang ZG, Zaloga C, Niewenhuis L, Gautam S 1994 p53-Immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats. Stroke 25:849-856
20. Hopkins SJ, Rothwell NJ 1995 Cytokines and the nervous system. I. Expression and recognition. Trends Neurosci 18:83-88
21. Aderka DJML, Vilcek J 1989 IL-6 inhibits lipopolysaccharide-induced tumour necrosis factor production in cultured human monocytes, U937 cells, and mice. J Immunol 143:3517-3523
22. Tilg H, Trehu E, Atkins MB, Dinarello CA, Mier JW 1994 Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumour necrosis factor receptor p55. Blood 83:113-118
23. Rodriguez M, Pavelko KD, McKinney CW, Leibowitz JL 1994 Recombinant human IL-6 suppresses demyelination in a viral model of multiple sclerosis. J Immunol 153:3811-3821
24. Rothwell NJ, Hopkins SJ 1995 Cytokines and the nervous system II: actions and mechanisms of action. Trends Neurosci 18:130-136
25. Rice JE, Vannucci RC, Brierley JB 1981 The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol 9:131-141
26. Andiné P, Thordstein M, Kjellmer I, Nordborg C, Thiringer K, Wennberg E, Hagberg H 1990 Evaluation of brain damage in a rat model of neonatal hypoxic-ischemia. J Neurosci Methods 35:253-260
27. Granholm T, Fröysa B, Lundström C, Wahab A, Midtvedt T, Söder O 1992 Cytokine responsiveness in germfree and conventional NMRI mice. Cytokine 4:545-550
28. Gustafsson K, Söder O, Pöllänen P, Ritzén EM 1988 Isolation and partial characterization of interleukin-1-like factor from rat testis interstitial fluid. J Reprod Immunol 14:139-150
29. VanSnick J, Cayphas S, Vink A, Uyttenhove C, Coulie PG, Rubira MR. Simpson RJ 1986 Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas. Proc Natl Acad Sci USA 83:9679-9683
30. Minami M, Kurashi Y, Yabuuchi K, Yamazaki A, Satoh M 1992 Induction of interleukin-1β mRNA in rat brain after transient forebrain ischemia. J Neurochem 58:390-392
31. Yabuuchi K, Minami M, Katsumata S, Yamazaki A, Satoh M 1994 An in situ hybridization study on inlerleukin-1β mRNA induced by transient forebrain ischemia in the rat. Mol Brain Res 26:135-142
32. Yamasaki Y, Matsuura N, Shozuhara H, Onodera H, Itoyama Y, Kogure K 1995 Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats. Stroke 26:676-681
33. Vannucci RC 1993 Experimental models of perinatal hypoxic-ischemic brain damage. APMIS Suppl 101:89-95
34. Amould T, Michiels C, Remacle J 1993 Increased PMN adherence on endothelial cells after hypoxia: involvement of PAF, CD18/CD11b, and ICAM-1. Am J Physiol 264:C1102-C1110
35. Kim JS, Chopp M, Chen H, Levine SR, Carey JL, Welch KMA 1995 Adhesive glycoproteins CD11a and CD 18 are upregulated in the leukocytes from patients with ischemic attacks. J Neurol Sci 128:45-50
36. McRae A, Gilland E, Bona E, Hagberg H 1994 Microglia activation after neonatal hypoxic-ischemia. Dev Brain Res 84:245-252
37. Gehrmann J, Matsumoto Y, Kreutzberg GW 1995 Microglia: intrinsic immunoeffector cell of the brain. Brain Res Rev 20:269-287
38. Gelbard HA, Dzenko KA, DiLoeto D, del Cerro C, del Cerro M, Epstein LG 1993 Neurotoxic effects of tumor necrosis factor alpha in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: implications for AIDS neuropathogenesis. Dev Neurosci 15:417-422
39. Chao CC, Hu S 1994 Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures. Dev Neurosci 16:172-179
40. Giulian D, Li J, Li X, George J, Rutecki PA 1994 The impact of microglia-derived cytokines upon gliosis in the CNS. Dev Neurosci 16:128-136
41. Kuroda Y, Shimamoto Y 1991 Human tumor necrosis factor-α augments experimental allergic encephalomyelitis in rats. J Neuroimmunol 34:159-164
42. Selmaj KW, Raine CS 1988 Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 23:339-346
43. Schotanus K, Tilders FJH, Berkenbosch F 1993 Human recombinant interleukin-1 receptor antagonist prevents adrenocorticotropin, but not interleukin-6 responses to bacterial endotoxin. Endocrinology 133:2461-2468
44. Shohami E, Novikov M, Bass R, Yamin A, Gallily R 1994 Closed head injury triggers early production of TNFα and IL-6 by brain tissue. J Cereb Blood Flow Metab 14:615-619
45. Kishimoto T, Akira A, Taga T 1992 Interleukin-6 and its receptor: a paradigm for cytokines. Science 258:593-597
46. Adinolfi M 1993 Infectious diseases in pregnancy cytokines and neurological impairment: an hypotesis. Dev Med Child Neurol 35:549-558
47. Nishida T, Nishono N, Takano M, Sekiguchi Y, Kawai K, Mizuno K, Nakai S, Masui Y, Harai Y 1989 Molecular cloning and expression of rat interleukin-1α cDNA. J Biochem 105:351-357
48. Northermann W, Braciak TA, Hattori M, Lee F, Fey GH 1989 Structure of the rat interleukin 6 gene and its expression in macrophage-derived cells. J Biol Chem 264:16072-16082