Poly(I : C) induces expressions of MMP-1, -2, and -3 through various signaling pathways including IRF3 in human skin fibroblasts

Journal of Dermatological Science

Volumn 80, Issue 1, 2015, Pages 54-60

  Yao, Cheng ^a,b,c   Lee, Dong Hun ^a,b,c   Oh, Jang Hee ^a,b,c   Kim, Min Kyoung ^a,b,c   Kim, Kyu Han ^a,b,c   Park, Chi Hyun ^a,b,c   Chung, Jin Ho ^a,b,c  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Seoul National University Hospital   (South Korea)

Author keywords

IRF3; MMP; Poly(I:C); TLR3

Indexed keywords

GELATINASE A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERSTITIAL COLLAGENASE; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; SMALL INTERFERING RNA; STROMELYSIN; I KAPPA B; IRF3 PROTEIN, HUMAN; MATRIX METALLOPROTEINASE; NF-KAPPAB INHIBITOR ALPHA; POLYNUCLEOTIDE; POLYRIBOINOSINIC-POLYRIBOCYTIDYLIC ACID; TLR3 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 3;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MMP 1 GENE; MMP 2 GENE; MMP 3 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN FIBROBLAST; WESTERN BLOTTING; CELL CULTURE; CUTANEOUS PARAMETERS; DRUG EFFECTS; FIBROBLAST; MALE; METABOLISM; SIGNAL TRANSDUCTION; SKIN;

CELLS, CULTURED; FIBROBLASTS; HUMANS; I-KAPPA B PROTEINS; INTERFERON REGULATORY FACTOR-3; MALE; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASES, SECRETED; POLYNUCLEOTIDES; SKIN; SKIN AGING; TOLL-LIKE RECEPTOR 3;

EID: 84939483721     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2015.06.017     Document Type: Article

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