Homozygous deletion of the LGI1 gene in mice leads to developmental abnormalities resulting in cortical dysplasia

Brain Pathology

Volumn 25, Issue 5, 2015, Pages 587-597

  Silva, Jeane ^a   Sharma, Suash ^a   Cowell, John K ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

cortical dysplasia; LGI1; mouse model; neurite outgrowth

Indexed keywords

LGI1 PROTEIN; PROTEIN; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXP2; TRANSCRIPTION FACTOR TBR1; UNCLASSIFIED DRUG; LGI1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; AUDITORY CORTEX; BRAIN CELL; BRAIN CORTEX; CELL COUNT; CELL MIGRATION; CONTROLLED STUDY; CORTICAL DYSPLASIA; DENDRITE; DEVELOPMENTAL DISORDER; ELECTRON MICROSCOPY; GENE DELETION; GOLGI COMPLEX; GOLGI STAIN; HIPPOCAMPUS; HOMOZYGOTE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; MOUSE; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVE FIBER; NERVE FIBER GROWTH; NEURAL STEM CELL; NEURITE; NISSL STAINING; NONHUMAN; PHENOTYPE; POSTSYNAPTIC DENSITY; PROTEIN DEPLETION; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; SOMATOSENSORY CORTEX; SYNAPSE; ANIMAL; AXON; CELL MOTION; DENDRITIC SPINE; GENETICS; PATHOLOGY; ULTRASTRUCTURE;

ANIMALS; AXONS; CELL MOVEMENT; DENDRITIC SPINES; GENE DELETION; HOMOZYGOTE; MALFORMATIONS OF CORTICAL DEVELOPMENT; MICE; NEURITES; PROTEINS; SYNAPSES;

EID: 84939470224     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/bpa.12225     Document Type: Article

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