메뉴 건너뛰기




Volumn 367, Issue 1, 2015, Pages 26-33

Exosomes: Emerging biomarkers and targets for ovarian cancer

Author keywords

Exosomes; Ovarian cancer; Protein; RNA

Indexed keywords

BIOLOGICAL MARKER; CURCUMIN; RAB PROTEIN; RAB27A PROTEIN; ANTINEOPLASTIC AGENT; TUMOR MARKER;

EID: 84939269936     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2015.07.014     Document Type: Review
Times cited : (139)

References (69)
  • 1
    • 0020956787 scopus 로고
    • Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor
    • Pan B.T., Johnstone R.M. Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Cell 1983, 33:967-978.
    • (1983) Cell , vol.33 , pp. 967-978
    • Pan, B.T.1    Johnstone, R.M.2
  • 2
    • 0023645106 scopus 로고
    • Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)
    • Johnstone R.M., Adam M., Hammond J.R., Orr L., Turbide C. Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J. Biol. Chem 1987, 262:9412-9420.
    • (1987) J. Biol. Chem , vol.262 , pp. 9412-9420
    • Johnstone, R.M.1    Adam, M.2    Hammond, J.R.3    Orr, L.4    Turbide, C.5
  • 3
    • 79960096964 scopus 로고    scopus 로고
    • Exosomes: secreted vesicles and intercellular communications
    • Théry C. Exosomes: secreted vesicles and intercellular communications. F1000 Biol. Rep 2011, 3:15.
    • (2011) F1000 Biol. Rep , vol.3 , pp. 15
    • Théry, C.1
  • 4
    • 68849129712 scopus 로고    scopus 로고
    • Membrane vesicles as conveyors of immune responses
    • Théry C., Ostrowski M., Segura E. Membrane vesicles as conveyors of immune responses. Nat. Rev. Immunol 2009, 9:581-593.
    • (2009) Nat. Rev. Immunol , vol.9 , pp. 581-593
    • Théry, C.1    Ostrowski, M.2    Segura, E.3
  • 7
    • 84886387008 scopus 로고    scopus 로고
    • Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
    • Christianson H.C., Svensson K.J., van Kuppevelt T.H., Li J.P., Belting M. Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:17380-17385.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 17380-17385
    • Christianson, H.C.1    Svensson, K.J.2    van Kuppevelt, T.H.3    Li, J.P.4    Belting, M.5
  • 8
    • 84879046970 scopus 로고    scopus 로고
    • Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1
    • Svensson K.J., Christianson H.C., Wittrup A., Bourseau-Guilmain E., Lindqvist E., Svensson L.M., et al. Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1. J. Biol. Chem 2013, 288:17713-17724.
    • (2013) J. Biol. Chem , vol.288 , pp. 17713-17724
    • Svensson, K.J.1    Christianson, H.C.2    Wittrup, A.3    Bourseau-Guilmain, E.4    Lindqvist, E.5    Svensson, L.M.6
  • 9
    • 84890904610 scopus 로고    scopus 로고
    • Body fluid exosomes promote secretion of inflammatory cytokines in monocytic cells via Toll-like receptor signaling
    • Bretz N.P., Ridinger J., Rupp A.K., Rimbach K., Keller S., Rupp C., et al. Body fluid exosomes promote secretion of inflammatory cytokines in monocytic cells via Toll-like receptor signaling. J. Biol. Chem 2013, 288:36691-36702.
    • (2013) J. Biol. Chem , vol.288 , pp. 36691-36702
    • Bretz, N.P.1    Ridinger, J.2    Rupp, A.K.3    Rimbach, K.4    Keller, S.5    Rupp, C.6
  • 10
    • 79955548092 scopus 로고    scopus 로고
    • Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC
    • Battke C., Ruiss R., Welsch U., Wimberger P., Lang S., Jochum S., et al. Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC. Cancer Immunol. Immunother 2011, 60:639-648.
    • (2011) Cancer Immunol. Immunother , vol.60 , pp. 639-648
    • Battke, C.1    Ruiss, R.2    Welsch, U.3    Wimberger, P.4    Lang, S.5    Jochum, S.6
  • 11
    • 79551610187 scopus 로고    scopus 로고
    • Exosomes in the ascites of ovarian cancer patients: origin and effects on anti-tumor immunity
    • Peng P., Yan Y., Keng S. Exosomes in the ascites of ovarian cancer patients: origin and effects on anti-tumor immunity. Oncol. Rep 2011, 25:749-762.
    • (2011) Oncol. Rep , vol.25 , pp. 749-762
    • Peng, P.1    Yan, Y.2    Keng, S.3
  • 13
    • 24644435853 scopus 로고    scopus 로고
    • Dexosomes as a therapeutic cancer vaccine: from bench to bedside
    • Le Pecq J.B. Dexosomes as a therapeutic cancer vaccine: from bench to bedside. Blood Cells Mol. Dis 2005, 35:129-135.
    • (2005) Blood Cells Mol. Dis , vol.35 , pp. 129-135
    • Le Pecq, J.B.1
  • 14
    • 21244465706 scopus 로고    scopus 로고
    • An analysis of variability in the manufacturing of dexosomes: implications for development of an autologous therapy
    • Patel S., Mehta-Damani A., Shu H., Le Pecq J.B. An analysis of variability in the manufacturing of dexosomes: implications for development of an autologous therapy. Biotechnol. Bioeng 2005, 92:238-249.
    • (2005) Biotechnol. Bioeng , vol.92 , pp. 238-249
    • Patel, S.1    Mehta-Damani, A.2    Shu, H.3    Le Pecq, J.B.4
  • 16
    • 67650481175 scopus 로고    scopus 로고
    • Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease
    • Di Vizio D., Kim J., Hager M.H., Morello M., Yang W., Lafargue C.J., et al. Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Res 2009, 69:5601-5609.
    • (2009) Cancer Res , vol.69 , pp. 5601-5609
    • Di Vizio, D.1    Kim, J.2    Hager, M.H.3    Morello, M.4    Yang, W.5    Lafargue, C.J.6
  • 17
    • 84874600636 scopus 로고    scopus 로고
    • Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids
    • Tauro B.J., Greening D.W., Mathias R.A., Mathivanan S., Ji H., Simpson R.J. Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Mol. Cell. Proteomics 2013, 12:587-598.
    • (2013) Mol. Cell. Proteomics , vol.12 , pp. 587-598
    • Tauro, B.J.1    Greening, D.W.2    Mathias, R.A.3    Mathivanan, S.4    Ji, H.5    Simpson, R.J.6
  • 19
    • 77955406553 scopus 로고    scopus 로고
    • Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg)
    • Szajnik M., Czystowska M., Szczepanski M.J., Mandapathil M., Whiteside T.L. Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg). PLoS ONE 2010, 5:e11469.
    • (2010) PLoS ONE , vol.5 , pp. e11469
    • Szajnik, M.1    Czystowska, M.2    Szczepanski, M.J.3    Mandapathil, M.4    Whiteside, T.L.5
  • 20
    • 36348935057 scopus 로고    scopus 로고
    • Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM
    • Runz S., Keller S., Rupp C., Stoeck A., Issa Y., Koensgen D., et al. Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM. Gynecol. Oncol 2007, 107:563-571.
    • (2007) Gynecol. Oncol , vol.107 , pp. 563-571
    • Runz, S.1    Keller, S.2    Rupp, C.3    Stoeck, A.4    Issa, Y.5    Koensgen, D.6
  • 21
    • 31544437691 scopus 로고    scopus 로고
    • A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44
    • Stoeck A., Keller S., Riedle S., Sanderson M.P., Runz S., Le Naour F., et al. A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44. Biochem. J. 2006, 393:609-618.
    • (2006) Biochem. J. , vol.393 , pp. 609-618
    • Stoeck, A.1    Keller, S.2    Riedle, S.3    Sanderson, M.P.4    Runz, S.5    Le Naour, F.6
  • 22
    • 84874413414 scopus 로고    scopus 로고
    • Characterization and proteomic analysis of ovarian cancer-derived exosomes
    • Liang B., Peng P., Chen S., Li L., Zhang M., Cao D., et al. Characterization and proteomic analysis of ovarian cancer-derived exosomes. J. Proteomics 2013, 80:171-182.
    • (2013) J. Proteomics , vol.80 , pp. 171-182
    • Liang, B.1    Peng, P.2    Chen, S.3    Li, L.4    Zhang, M.5    Cao, D.6
  • 24
    • 0037318306 scopus 로고    scopus 로고
    • ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles
    • Gutwein P., Mechtersheimer S., Riedle S., Stoeck A., Gast D., Joumaa S., et al. ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles. FASEB J. 2003, 17:292-294.
    • (2003) FASEB J. , vol.17 , pp. 292-294
    • Gutwein, P.1    Mechtersheimer, S.2    Riedle, S.3    Stoeck, A.4    Gast, D.5    Joumaa, S.6
  • 25
    • 84939287429 scopus 로고    scopus 로고
    • Ectodomain of ADAM15 is shed from secretory exosomes
    • pii: 2901
    • Lee H.D., Kim Y.H., Koo B.H., Kim D.S. Ectodomain of ADAM15 is shed from secretory exosomes. BMB Rep 2014, pii: 2901.
    • (2014) BMB Rep
    • Lee, H.D.1    Kim, Y.H.2    Koo, B.H.3    Kim, D.S.4
  • 26
    • 63649092087 scopus 로고    scopus 로고
    • Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes
    • Keller S., König A.K., Marmé F., Runz S., Wolterink S., Koensgen D., et al. Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes. Cancer Lett 2009, 278:73-81.
    • (2009) Cancer Lett , vol.278 , pp. 73-81
    • Keller, S.1    König, A.K.2    Marmé, F.3    Runz, S.4    Wolterink, S.5    Koensgen, D.6
  • 29
    • 45449093192 scopus 로고    scopus 로고
    • MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
    • Taylor D.D., Gercel-Taylor C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol. Oncol 2008, 110:13-21.
    • (2008) Gynecol. Oncol , vol.110 , pp. 13-21
    • Taylor, D.D.1    Gercel-Taylor, C.2
  • 30
    • 84891514593 scopus 로고    scopus 로고
    • Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200
    • Kobayashi M., Salomon C., Tapia J., Illanes S.E., Mitchell M.D., Rice G.E. Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200. J. Transl. Med 2014, 12:4.
    • (2014) J. Transl. Med , vol.12 , pp. 4
    • Kobayashi, M.1    Salomon, C.2    Tapia, J.3    Illanes, S.E.4    Mitchell, M.D.5    Rice, G.E.6
  • 31
    • 84860802273 scopus 로고    scopus 로고
    • Exosomes in cancer microenvironment and beyond: have we overlooked these extracellular messengers?
    • Ge R., Tan E., Sharghi-Namini S., Asada H.H. Exosomes in cancer microenvironment and beyond: have we overlooked these extracellular messengers?. Cancer Microenviron 2012, 5:323-332.
    • (2012) Cancer Microenviron , vol.5 , pp. 323-332
    • Ge, R.1    Tan, E.2    Sharghi-Namini, S.3    Asada, H.H.4
  • 32
    • 84896735649 scopus 로고    scopus 로고
    • Exosomes: an overview of biogenesis, composition and role in ovarian cancer
    • Beach A., Zhang H.G., Ratajczak M.Z., Kakar S.S. Exosomes: an overview of biogenesis, composition and role in ovarian cancer. J. Ovarian Res 2014, 7:14.
    • (2014) J. Ovarian Res , vol.7 , pp. 14
    • Beach, A.1    Zhang, H.G.2    Ratajczak, M.Z.3    Kakar, S.S.4
  • 33
    • 84929939631 scopus 로고    scopus 로고
    • The passenger strand, miR-21-3p, plays a role in mediating cisplatin resistance in ovarian cancer cells
    • Pink R.C., Samuel P., Massa D., Caley D.P., Brooks S.A., Carter D.R. The passenger strand, miR-21-3p, plays a role in mediating cisplatin resistance in ovarian cancer cells. Gynecol. Oncol 2015, 137:143-151.
    • (2015) Gynecol. Oncol , vol.137 , pp. 143-151
    • Pink, R.C.1    Samuel, P.2    Massa, D.3    Caley, D.P.4    Brooks, S.A.5    Carter, D.R.6
  • 34
    • 84906834990 scopus 로고    scopus 로고
    • Exosome-derived miRNAs and ovarian carcinoma progression
    • Vaksman O., Tropé C., Davidson B., Reich R. Exosome-derived miRNAs and ovarian carcinoma progression. Carcinogenesis 2014, 35:2113-2120.
    • (2014) Carcinogenesis , vol.35 , pp. 2113-2120
    • Vaksman, O.1    Tropé, C.2    Davidson, B.3    Reich, R.4
  • 35
    • 84892674862 scopus 로고    scopus 로고
    • Exosomes in plasma of patients with ovarian carcinoma: potential biomarkers of tumor progression and response to therapy
    • Szajnik M., Derbis M., Lach M., Patalas P., Michalak M., Drzewiecka H., et al. Exosomes in plasma of patients with ovarian carcinoma: potential biomarkers of tumor progression and response to therapy. Gynecol. Obstet. (Sunnyvale) 2013, 3(Suppl. 4).
    • (2013) Gynecol. Obstet. (Sunnyvale) , vol.3
    • Szajnik, M.1    Derbis, M.2    Lach, M.3    Patalas, P.4    Michalak, M.5    Drzewiecka, H.6
  • 36
    • 84863010943 scopus 로고    scopus 로고
    • Secretion of annexin A3 from ovarian cancer cells and its association with platinum resistance in ovarian cancer patients
    • Yin J., Yan X., Yao X., Zhang Y., Shan Y., Mao N., et al. Secretion of annexin A3 from ovarian cancer cells and its association with platinum resistance in ovarian cancer patients. J. Cell. Mol. Med 2012, 16:337-348.
    • (2012) J. Cell. Mol. Med , vol.16 , pp. 337-348
    • Yin, J.1    Yan, X.2    Yao, X.3    Zhang, Y.4    Shan, Y.5    Mao, N.6
  • 37
    • 80054717963 scopus 로고    scopus 로고
    • Exosomes from ovarian cancer cells induce adipose tissue-derived mesenchymal stem cells to acquire the physical and functional characteristics of tumor-supporting myofibroblasts
    • Cho J.A., Park H., Lim E.H., Kim K.H., Choi J.S., Lee J.H., et al. Exosomes from ovarian cancer cells induce adipose tissue-derived mesenchymal stem cells to acquire the physical and functional characteristics of tumor-supporting myofibroblasts. Gynecol. Oncol 2011, 123:379-386.
    • (2011) Gynecol. Oncol , vol.123 , pp. 379-386
    • Cho, J.A.1    Park, H.2    Lim, E.H.3    Kim, K.H.4    Choi, J.S.5    Lee, J.H.6
  • 38
    • 20244390010 scopus 로고    scopus 로고
    • Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells
    • Gutwein P., Stoeck A., Riedle S., Gast D., Runz S., Condon T.P., et al. Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells. Clin. Cancer Res 2005, 11:2492-2501.
    • (2005) Clin. Cancer Res , vol.11 , pp. 2492-2501
    • Gutwein, P.1    Stoeck, A.2    Riedle, S.3    Gast, D.4    Runz, S.5    Condon, T.P.6
  • 39
    • 27644524811 scopus 로고    scopus 로고
    • Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells
    • Safaei R., Larson B.J., Cheng T.C., Gibson M.A., Otani S., Naerdemann W. Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells. Mol. Cancer Ther 2005, 4:1595-1604.
    • (2005) Mol. Cancer Ther , vol.4 , pp. 1595-1604
    • Safaei, R.1    Larson, B.J.2    Cheng, T.C.3    Gibson, M.A.4    Otani, S.5    Naerdemann, W.6
  • 40
    • 14844334129 scopus 로고    scopus 로고
    • Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects
    • Taylor D.D., Gercel-Taylor C. Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects. Br. J. Cancer 2005, 92:305-311.
    • (2005) Br. J. Cancer , vol.92 , pp. 305-311
    • Taylor, D.D.1    Gercel-Taylor, C.2
  • 41
    • 84862007577 scopus 로고    scopus 로고
    • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
    • Peinado H., Alečković M., Lavotshkin S., Matei I., Costa-Silva B., Moreno-Bueno G., et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat. Med 2012, 18:883-891.
    • (2012) Nat. Med , vol.18 , pp. 883-891
    • Peinado, H.1    Alečković, M.2    Lavotshkin, S.3    Matei, I.4    Costa-Silva, B.5    Moreno-Bueno, G.6
  • 42
    • 84861589643 scopus 로고    scopus 로고
    • Mesenchymal cell interaction with ovarian cancer cells triggers pro-metastatic properties
    • Lis R., Touboul C., Raynaud C.M., Malek J.A., Suhre K., Mirshahi M., et al. Mesenchymal cell interaction with ovarian cancer cells triggers pro-metastatic properties. PLoS ONE 2012, 7:e38340.
    • (2012) PLoS ONE , vol.7 , pp. e38340
    • Lis, R.1    Touboul, C.2    Raynaud, C.M.3    Malek, J.A.4    Suhre, K.5    Mirshahi, M.6
  • 43
    • 0024549349 scopus 로고
    • Induction of angiogenesis during the transition from hyperplasia to neoplasia
    • Folkman J., Watson K., Ingber D., Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 1989, 339:58-61.
    • (1989) Nature , vol.339 , pp. 58-61
    • Folkman, J.1    Watson, K.2    Ingber, D.3    Hanahan, D.4
  • 44
    • 84879419464 scopus 로고    scopus 로고
    • Leukemia cell to endothelial cell communication via exosomal miRNAs
    • Umezu T., Ohyashiki K., Kuroda M., Ohyashiki J.H. Leukemia cell to endothelial cell communication via exosomal miRNAs. Oncogene 2013, 32:2747-2755.
    • (2013) Oncogene , vol.32 , pp. 2747-2755
    • Umezu, T.1    Ohyashiki, K.2    Kuroda, M.3    Ohyashiki, J.H.4
  • 45
    • 84876927914 scopus 로고    scopus 로고
    • Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
    • Kucharzewska P., Christianson H.C., Welch J.E., Svensson K.J., Fredlund E., Ringnér M., et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:7312-7317.
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 7312-7317
    • Kucharzewska, P.1    Christianson, H.C.2    Welch, J.E.3    Svensson, K.J.4    Fredlund, E.5    Ringnér, M.6
  • 47
    • 84872110263 scopus 로고    scopus 로고
    • Assessing the risk of ovarian malignancy in asymptomatic women with abnormal CA 125 and transvaginal ultrasound scans in the prostate, lung, colorectal, and ovarian screening trial
    • Partridge E.E., Greenlee R.T., Riley T.L., Commins J., Ragard L., Xu J.L., et al. Assessing the risk of ovarian malignancy in asymptomatic women with abnormal CA 125 and transvaginal ultrasound scans in the prostate, lung, colorectal, and ovarian screening trial. Obstet. Gynecol 2013, 121:25-31.
    • (2013) Obstet. Gynecol , vol.121 , pp. 25-31
    • Partridge, E.E.1    Greenlee, R.T.2    Riley, T.L.3    Commins, J.4    Ragard, L.5    Xu, J.L.6
  • 49
    • 84900307606 scopus 로고    scopus 로고
    • Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
    • Im H., Shao H., Park Y.I., Peterson V.M., Castro C.M., Weissleder R., et al. Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor. Nat. Biotechnol 2014, 32:490-495.
    • (2014) Nat. Biotechnol , vol.32 , pp. 490-495
    • Im, H.1    Shao, H.2    Park, Y.I.3    Peterson, V.M.4    Castro, C.M.5    Weissleder, R.6
  • 51
    • 84911966357 scopus 로고    scopus 로고
    • Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis
    • Melo S.A., Sugimoto H., O'Connell J.T., Kato N., Villanueva A., Vidal A., et al. Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Cancer Cell 2014, 26:707-721.
    • (2014) Cancer Cell , vol.26 , pp. 707-721
    • Melo, S.A.1    Sugimoto, H.2    O'Connell, J.T.3    Kato, N.4    Villanueva, A.5    Vidal, A.6
  • 52
    • 84939287430 scopus 로고    scopus 로고
    • Integrated systems for exosome investigation
    • pii: S1046-2023(15)00161-00169. [Epub ahead of print]
    • Peterson M.F., Otoc N., Sethi J.K., Gupta A., Antes T.J. Integrated systems for exosome investigation. Methods 2015, pii: S1046-2023(15)00161-00169. [Epub ahead of print].
    • (2015) Methods
    • Peterson, M.F.1    Otoc, N.2    Sethi, J.K.3    Gupta, A.4    Antes, T.J.5
  • 55
    • 75749091133 scopus 로고    scopus 로고
    • Microfluidic isolation and transcriptome analysis of serum microvesicles
    • Chen C., Skog J., Hsu C.H., Lessard R.T., Balaj L., Wurdinger T., et al. Microfluidic isolation and transcriptome analysis of serum microvesicles. Lab Chip 2010, 10:505-511.
    • (2010) Lab Chip , vol.10 , pp. 505-511
    • Chen, C.1    Skog, J.2    Hsu, C.H.3    Lessard, R.T.4    Balaj, L.5    Wurdinger, T.6
  • 56
    • 84870918654 scopus 로고    scopus 로고
    • Microfluidic filtration system to isolate extracellular vesicles from blood
    • Davies R.T., Kim J., Jang S.C., Choi E.J., Gho Y.S., Park J. Microfluidic filtration system to isolate extracellular vesicles from blood. Lab Chip 2012, 12:5202-5210.
    • (2012) Lab Chip , vol.12 , pp. 5202-5210
    • Davies, R.T.1    Kim, J.2    Jang, S.C.3    Choi, E.J.4    Gho, Y.S.5    Park, J.6
  • 57
    • 84906700936 scopus 로고    scopus 로고
    • Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology
    • He M., Crow J., Roth M., Zeng Y., Godwin A.K. Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology. Lab Chip 2014, 14:3773-3780.
    • (2014) Lab Chip , vol.14 , pp. 3773-3780
    • He, M.1    Crow, J.2    Roth, M.3    Zeng, Y.4    Godwin, A.K.5
  • 58
    • 84891363865 scopus 로고    scopus 로고
    • Magnetic nanosensor for detection and profiling of erythrocyte-derived microvesicles
    • Rho J., Chung J., Im H., Liong M., Shao H., Castro C.M., et al. Magnetic nanosensor for detection and profiling of erythrocyte-derived microvesicles. ACS Nano 2013, 7:11227-11233.
    • (2013) ACS Nano , vol.7 , pp. 11227-11233
    • Rho, J.1    Chung, J.2    Im, H.3    Liong, M.4    Shao, H.5    Castro, C.M.6
  • 60
    • 84863199863 scopus 로고    scopus 로고
    • Get on the exosome bus with ALIX
    • Hurley J.H., Odorizzi G. Get on the exosome bus with ALIX. Nat. Cell Biol 2012, 14:654-655.
    • (2012) Nat. Cell Biol , vol.14 , pp. 654-655
    • Hurley, J.H.1    Odorizzi, G.2
  • 61
    • 79952281752 scopus 로고    scopus 로고
    • Tumor immune surveillance and ovarian cancer: lessons on immune mediated tumor rejection or tolerance
    • Kandalaft L.E., Motz G.T., Duraiswamy J., Coukos G. Tumor immune surveillance and ovarian cancer: lessons on immune mediated tumor rejection or tolerance. Cancer Metastasis Rev 2011, 30:141-151.
    • (2011) Cancer Metastasis Rev , vol.30 , pp. 141-151
    • Kandalaft, L.E.1    Motz, G.T.2    Duraiswamy, J.3    Coukos, G.4
  • 63
    • 18144372419 scopus 로고    scopus 로고
    • Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of the first phase I clinical trial
    • Escudier B., Dorval T., Chaput N., André F., Caby M.P., Novault S., et al. Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of the first phase I clinical trial. J. Transl. Med 2005, 3:10.
    • (2005) J. Transl. Med , vol.3 , pp. 10
    • Escudier, B.1    Dorval, T.2    Chaput, N.3    André, F.4    Caby, M.P.5    Novault, S.6
  • 64
    • 18144369346 scopus 로고    scopus 로고
    • A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer
    • Morse M.A., Garst J., Osada T., Khan S., Hobeika A., Clay T.M., et al. A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer. J. Transl. Med 2005, 3:9.
    • (2005) J. Transl. Med , vol.3 , pp. 9
    • Morse, M.A.1    Garst, J.2    Osada, T.3    Khan, S.4    Hobeika, A.5    Clay, T.M.6
  • 67
    • 77956264919 scopus 로고    scopus 로고
    • A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes
    • Sun D., Zhuang X., Xiang X., Liu Y., Zhang S., Liu C., et al. A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes. Mol. Ther 2010, 18:1606-1614.
    • (2010) Mol. Ther , vol.18 , pp. 1606-1614
    • Sun, D.1    Zhuang, X.2    Xiang, X.3    Liu, Y.4    Zhang, S.5    Liu, C.6
  • 68
    • 84879686252 scopus 로고    scopus 로고
    • Grape exosome-like nanoparticles induce intestinal stem cells and protect mice from DSS-induced colitis
    • Ju S., Mu J., Dokland T., Zhuang X., Wang Q., Jiang H., et al. Grape exosome-like nanoparticles induce intestinal stem cells and protect mice from DSS-induced colitis. Mol. Ther 2013, 21:1345-1357.
    • (2013) Mol. Ther , vol.21 , pp. 1345-1357
    • Ju, S.1    Mu, J.2    Dokland, T.3    Zhuang, X.4    Wang, Q.5    Jiang, H.6
  • 69
    • 84885450849 scopus 로고    scopus 로고
    • Combined effects of curcumin and triptolide on an ovarian cancer cell line
    • Cai Y.Y., Lin W.P., Li A.P., Xu J.Y. Combined effects of curcumin and triptolide on an ovarian cancer cell line. Asian Pac. J. Cancer Prev 2013, 14:4267-4271.
    • (2013) Asian Pac. J. Cancer Prev , vol.14 , pp. 4267-4271
    • Cai, Y.Y.1    Lin, W.P.2    Li, A.P.3    Xu, J.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.