Methylenetetrahydrofolate reductase C677T polymorphism is associated with increased risk of coronary artery disease in young South African Indians

Gene

Volumn 571, Issue 1, 2015, Pages 28-32

  Ramkaran, Prithiksha ^a   Phulukdaree, Alisa ^b   Khan, Sajidah ^c   Moodley, Devapregasan ^a   Chuturgoon, Anil A ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b UNIVERSITY OF PRETORIA   (South Africa)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

Homocysteine; Methylenetetrahydrofolate reductase; MTHFR C677T; Premature coronary artery disease; Single nucleotide polymorphism

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); C REACTIVE PROTEIN; CHOLESTEROL; FOLIC ACID; GLUCOSE; HEMOGLOBIN A1C; HOMOCYSTEINE; INSULIN; LOW DENSITY LIPOPROTEIN; METHIONINE; METHYLENETETRAHYDROFOLIC ACID; TRIACYLGLYCEROL; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MTHFR PROTEIN, HUMAN;

ADULT; ARTICLE; CARDIOVASCULAR MORTALITY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FOLATE METABOLISM; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HIGH RISK PATIENT; HUMAN; INDIAN; MAJOR CLINICAL STUDY; MALE; METHYLATION; METHYLENETETRAHYDROFOLATE REDUCTASE GENE; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH AFRICAN; AMERICAN INDIAN; BLACK PERSON; ETHNOLOGY; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; RISK FACTOR; SOUTH AFRICA; YOUNG ADULT;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; CORONARY ARTERY DISEASE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INDIANS, SOUTH AMERICAN; LINKAGE DISEQUILIBRIUM; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SOUTH AFRICA; YOUNG ADULT;

EID: 84939267933     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2015.06.044     Document Type: Article

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