메뉴 건너뛰기




Volumn 135, Issue 4, 2012, Pages 506-512

Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians

Author keywords

Cad; Case control; Gene polymorphism; Homocysteine; MTHFR; Risk factors

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CHOLESTEROL; CYANOCOBALAMIN; EDETIC ACID; FOLIC ACID; HIGH DENSITY LIPOPROTEIN; HOMOCYSTEINE; LOW DENSITY LIPOPROTEIN;

EID: 84861925980     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (37)

References (34)
  • 1
    • 0033028586 scopus 로고    scopus 로고
    • Hyperhomocysteinemia, atherosclerosis and thrombosis
    • Cattaneo M. Hyperhomocysteinemia, atherosclerosis and thrombosis. Thromb Haemost 1999; 81: 165-76.
    • (1999) Thromb Haemost , vol.81 , pp. 165-176
    • Cattaneo, M.1
  • 2
    • 0028219672 scopus 로고
    • Relation of serum homocysteine and lipoprotein (a) concentrations to atherosclerotic disease in a prospective Finnish population based study
    • Alfthan G, Pekkanan J, Jauhiainen M, Pitkäniemi J, Karvonem M, Tuomilehto J. Relation of serum homocysteine and lipoprotein (a) concentrations to atherosclerotic disease in a prospective Finnish population based study. Atherosclerosis 1994; 106: 9-19.
    • (1994) Atherosclerosis , vol.106 , pp. 9-19
    • Alfthan, G.1    Pekkanan, J.2    Jauhiainen, M.3    Pitkäniemi, J.4    Karvonem, M.5    Tuomilehto, J.6
  • 3
    • 0037345584 scopus 로고    scopus 로고
    • Hyper homocysteinemia: A million ways to lose control
    • Faraci FM. Hyper homocysteinemia: A million ways to lose control. Arterioscler Thromb Basic Biol 2003; 23: 371-373.
    • (2003) Arterioscler Thromb Basic Biol , vol.23 , pp. 371-373
    • Faraci, F.M.1
  • 4
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: Evidence of causality from meta-analysis
    • Wald DS, Low M, Marris JK. Homocysteine and cardiovascular disease: evidence of causality from meta-analysis. BMJ 2002; 325: 1202-1206.
    • (2002) BMJ , vol.325 , pp. 1202-1206
    • Wald, D.S.1    Low, M.2    Marris, J.K.3
  • 5
    • 0035969545 scopus 로고    scopus 로고
    • Decrease rate of Coronary re-stenosis after lowering plasma homocysteine levels
    • Schnyder G, Roff M, Pin R, Flammer Y, Lange H, Eberli FR, et al. Decrease rate of Coronary re-stenosis after lowering plasma homocysteine levels. N Engl J Med 2001; 345: 1593-1600.
    • (2001) N Engl J Med , vol.345 , pp. 1593-1600
    • Schnyder, G.1    Roff, M.2    Pin, R.3    Flammer, Y.4    Lange, H.5    Eberli, F.R.6
  • 6
    • 27744471516 scopus 로고    scopus 로고
    • Meta-analysis of MTHFR 677 C→T polymorphism and coronary heart disease. Does totality of evidence support casual role for homocysteine and preventive potential of folate
    • Lewis SJ, Shah E, Smith GD. Meta-analysis of MTHFR 677 C→T polymorphism and coronary heart disease. Does totality of evidence support casual role for homocysteine and preventive potential of folate. BMJ 2005; 331: 1053-1070.
    • (2005) BMJ , vol.331 , pp. 1053-1070
    • Lewis, S.J.1    Shah, E.2    Smith, G.D.3
  • 7
    • 84857711683 scopus 로고    scopus 로고
    • Homocysteine and coronary heart disease: Meta-analysis of MTHFR case-control studies, avoiding publication bias
    • Clarke R, Bennett DA, Parish S, Verhoef P, Dötsch-Klerk M, et al. Homocysteine and coronary heart disease: Meta-analysis of MTHFR case-control studies, avoiding publication bias. PLoS Med 2012; 9 (2): e1001177.
    • (2012) PLoS Med , vol.9 , Issue.2
    • Clarke, R.1    Bennett, D.A.2    Parish, S.3    Verhoef, P.4    Dötsch-Klerk, M.5
  • 8
    • 0031662210 scopus 로고    scopus 로고
    • MTHFR association with arteriosclerotic vascular disease?
    • Fletcher O, Kessling AM. MTHFR association with arteriosclerotic vascular disease? Hum Genet 1999; 103: 11-21.
    • (1999) Hum Genet , vol.103 , pp. 11-21
    • Fletcher, O.1    Kessling, A.M.2
  • 9
    • 84861942486 scopus 로고    scopus 로고
    • Methylene tetra hydrofolatate reductase gene polymorphism and hyperhomocysteinemia as risk factors for coronary heart disease in Indian population
    • Sastry BKS, Nair KG, Nair SR, Ashavaid TF, Dalal JJ, Eghilm FF. Methylene tetra hydrofolatate reductase gene polymorphism and hyperhomocysteinemia as risk factors for coronary heart disease in Indian population. J Assoc Physicians India 2002; 24: 509-515.
    • (2002) J Assoc Physicians India , vol.24 , pp. 509-515
    • Sastry, B.K.S.1    Nair, K.G.2    Nair, S.R.3    Ashavaid, T.F.4    Dalal, J.J.5    Eghilm, F.F.6
  • 10
    • 0035223194 scopus 로고    scopus 로고
    • Absence of association between serum homocysteine levels and coronary artery disease in South Indian males
    • Deepa R, Velmurugan K, Saravanan G, Karkuzhali K, Dwarkanath V, Mohan V, et al. Absence of association between serum homocysteine levels and coronary artery disease in South Indian males. Indian Heart J 2001; 53: 44-47.
    • (2001) Indian Heart J , vol.53 , pp. 44-47
    • Deepa, R.1    Velmurugan, K.2    Saravanan, G.3    Karkuzhali, K.4    Dwarkanath, V.5    Mohan, V.6
  • 12
    • 0032061999 scopus 로고    scopus 로고
    • Plasma homocysteine levels in patients with coronary heart disease
    • Chako KA. Plasma homocysteine levels in patients with coronary heart disease. Indian Heart J 1998; 50: 295-299.
    • (1998) Indian Heart J , vol.50 , pp. 295-299
    • Chako, K.A.1
  • 13
    • 0034639623 scopus 로고    scopus 로고
    • Plasma homocysteine concentrations and risk of coronary heart disease in UK, Indian Asians and Europeans
    • Chambers JL, Obeid OA, Refsum H, Ueland P, Hackell D, Hooper J, et al. Plasma homocysteine concentrations and risk of coronary heart disease in UK, Indian Asians and Europeans. Lancet 2000; 355: 523-527.
    • (2000) Lancet , vol.355 , pp. 523-527
    • Chambers, J.L.1    Obeid, O.A.2    Refsum, H.3    Ueland, P.4    Hackell, D.5    Hooper, J.6
  • 15
    • 7244247022 scopus 로고    scopus 로고
    • Combination of Thrombophilia markers in acute myocardial infarction
    • Khare A, Ghosh K, Shetty S, Kulkarni B, Mohanty D. Combination of Thrombophilia markers in acute myocardial infarction. Indian J Med Sci 2004; 58: 381-388.
    • (2004) Indian J Med Sci , vol.58 , pp. 381-388
    • Khare, A.1    Ghosh, K.2    Shetty, S.3    Kulkarni, B.4    Mohanty, D.5
  • 16
    • 0036559670 scopus 로고    scopus 로고
    • MTHFR gene mutation and hyperhomocysteinemia as risk factors in coronary heart disease in Indian population
    • Nair KG, Nair SR, Ashavaid TF, Dalai JS, Eghlin FF. MTHFR gene mutation and hyperhomocysteinemia as risk factors in coronary heart disease in Indian population. J Assoc Physicians India 2002; 50: 9-15.
    • (2002) J Assoc Physicians India , vol.50 , pp. 9-15
    • Nair, K.G.1    Nair, S.R.2    Ashavaid, T.F.3    Dalai, J.S.4    Eghlin, F.F.5
  • 18
    • 0034934781 scopus 로고    scopus 로고
    • Homocysteine and elevated methylmalonic acid indicate a high prevalence of cobalamin defciency in Asian Indian
    • Refsum H, Yajnik CS, Gadkari M, Schneede J, Vollset stein E, Orning L, et al. Homocysteine and elevated methylmalonic acid indicate a high prevalence of cobalamin defciency in Asian Indian. Am J Clin Nutr 2001; 74: 233-241.
    • (2001) Am J Clin Nutr , vol.74 , pp. 233-241
    • Refsum, H.1    Yajnik, C.S.2    Gadkari, M.3    Schneede, J.4    Vollset Stein, E.5    Orning, L.6
  • 19
    • 73449147003 scopus 로고    scopus 로고
    • MTHFR gene C677T and A 1298C polymorphisms and homocysteine levels in primary open angle and primary closed angle glaucoma
    • Micheal S, Qamar R, Akhtar F, Khan MI, Khan WA, Ahmed A. MTHFR gene C677T and A 1298C polymorphisms and homocysteine levels in primary open angle and primary closed angle glaucoma. Mol Vis 2009; 15: 2268-2278.
    • (2009) Mol Vis , vol.15 , pp. 2268-2278
    • Micheal, S.1    Qamar, R.2    Akhtar, F.3    Khan, M.I.4    Khan, W.A.5    Ahmed, A.6
  • 20
    • 0142124397 scopus 로고    scopus 로고
    • NCEP ATP III guidelines incorporates global risk assessment
    • Gotto AM, NCEP ATP III guidelines incorporates global risk assessment. Am J Manag Care 2003; (Suppl): 1, 3.
    • (2003) Am J Manag Care , vol.1 , Issue.SUPPL. , pp. 3
    • Gotto, A.M.1
  • 23
    • 0034745480 scopus 로고    scopus 로고
    • Homozygocity For the C677→T Mutation of 5, 10-methylene Tetrahydrofolate Reductase and Total Plasma Homocysteine Are Not Associated With Greater Than Normal Risk of a First Myocardial Infarction In Northern Sweden
    • Thögersen AM, Nilsson TK, Dahlen GJ, Jan-Håkans K, Huhtasaari F, Hallmans G. Homozygocity for the C677→T mutation of 5, 10-methylene tetrahydrofolate reductase and total plasma homocysteine are not associated with greater than normal risk of a first myocardial infarction in Northern Sweden. Coron Artery Dis 2001; 12: 85-90.
    • (2001) Coron Artery Dis , vol.12 , pp. 85-90
    • Thögersen, A.M.1    Nilsson, T.K.2    Dahlen, G.J.3    Jan-Håkans, K.4    Huhtasaari, F.5    Hallmans, G.6
  • 24
    • 17644443495 scopus 로고    scopus 로고
    • Homocysteine and the methylene tetrahydrafolate reductase C677T allele in premature coronary artery disease. Case control and family studies
    • Pinto X, Vilaseca MA, Garcia - Giralt N, Ferrer I, Pala M, Meco JF, et al. Homocysteine and the methylene tetrahydrafolate reductase C677T allele in premature coronary artery disease. Case control and family studies. Eur J Clin Invest 2001; 31: 24-30.
    • (2001) Eur J Clin Invest , vol.31 , pp. 24-30
    • Pinto, X.1    Vilaseca, M.A.2    Garcia-Giralt, N.3    Ferrer, I.4    Pala, M.5    Meco, J.F.6
  • 25
    • 4444224055 scopus 로고    scopus 로고
    • Prevalence of methylene tetrahydrofolate polymorphism in South Indian population
    • Rama Devi RA, Govindhiah V, Ramakrishna G, Nausad SM. Prevalence of methylene tetrahydrofolate polymorphism in South Indian population. Curr Sci 2004; 86: 440-443.
    • (2004) Curr Sci , vol.86 , pp. 440-443
    • Rama Devi, R.A.1    Govindhiah, V.2    Ramakrishna, G.3    Nausad, S.M.4
  • 26
    • 0042769170 scopus 로고    scopus 로고
    • Relationship of systolic blood pressure with plasma homocysteine: Importance smoking status
    • Kennedys BP, Farag NH, Zieglar MG, Mills PJ. Relationship of systolic blood pressure with plasma homocysteine: importance smoking status. J Hypertens 2003, 21: 1307-1312.
    • (2003) J Hypertens , vol.21 , pp. 1307-1312
    • Kennedys, B.P.1    Farag, N.H.2    Zieglar, M.G.3    Mills, P.J.4
  • 27
    • 0035212179 scopus 로고    scopus 로고
    • The C677T mutation of the methylene tetrahydrofolate reductase gene is not associated with the risk of coronary artery disease or venous thrombosis among Chinese in Taiwan
    • Hsu LA, Ko YL, Wang SM, Chang CJ, Hsu TS, Chiang CW, et al. The C677T mutation of the methylene tetrahydrofolate reductase gene is not associated with the risk of coronary artery disease or venous thrombosis among Chinese in Taiwan. Hum Hered 2001; 51: 41-45.
    • (2001) Hum Hered , vol.51 , pp. 41-45
    • Hsu, L.A.1    Ko, Y.L.2    Wang, S.M.3    Chang, C.J.4    Hsu, T.S.5    Chiang, C.W.6
  • 28
    • 34248358966 scopus 로고    scopus 로고
    • Homocysteine, 5,10-methylene tetrehydrofolate reductase 677 C>T polymorphism, nutrient intake and incident cardiovascular disease in 24968 initially healthy women
    • Robert Y.L. ZEE, Samia Mora, Suzanne Cheng, Henry A Erlich, Klaus Lindpaintner, Nader R, et al. Homocysteine, 5,10-methylene tetrehydrofolate reductase 677 C>T polymorphism, nutrient intake and incident cardiovascular disease in 24968 initially healthy women. Clin Chem 2007; 53: 845-851.
    • (2007) Clin Chem , vol.53 , pp. 845-851
    • Zee, R.Y.L.1    Mora, S.2    Cheng, S.3    Erlich, H.A.4    Lindpaintner, K.5    Nader, R.6
  • 29
    • 58149399868 scopus 로고    scopus 로고
    • High plasma homocysteine is associated with the risk of coronary artery disease independent of methylene tetrahydrofolate reductase 677 C→T genes
    • Lin PT, Huang MC, Lee BJ, Chang CH, Tsai TP, Huang YC, et al. High plasma homocysteine is associated with the risk of coronary artery disease independent of methylene tetrahydrofolate reductase 677 C→T genes. Asia Pac J Clin Nutr 2008; 17: 330-338.
    • (2008) Asia Pac J Clin Nutr , vol.17 , pp. 330-338
    • Lin, P.T.1    Huang, M.C.2    Lee, B.J.3    Chang, C.H.4    Tsai, T.P.5    Huang, Y.C.6
  • 30
    • 46649094604 scopus 로고    scopus 로고
    • Plasma homocysteine levels and 677 C→T methylene tetrahydrofolate reductase gene polymorphism in patients with coronary artery disease of different severity
    • Rossoul F, Richter V, Hertschal B, Geisel J, Hermann W, Kuntze T, et al. Plasma homocysteine levels and 677 C→T methylene tetrahydrofolate reductase gene polymorphism in patients with coronary artery disease of different severity. Indian J Med Res 2008; 127: 154-158.
    • (2008) Indian J Med Res , vol.127 , pp. 154-158
    • Rossoul, F.1    Richter, V.2    Hertschal, B.3    Geisel, J.4    Hermann, W.5    Kuntze, T.6
  • 31
    • 85117738003 scopus 로고    scopus 로고
    • MTHFR polymorphism (C667→ T) hyperhomocystenemia, and risk of ischaemic cardiovascular disease and venous thromboembolism: Prospective and case control studies from Copenhagen City Heart Study
    • Frederiksen J, Juul K, Grande P, Jensen GB, Schroeder TV, Anne TH, et al. MTHFR polymorphism (C667→ T) hyperhomocystenemia, and risk of ischaemic cardiovascular disease and venous thromboembolism: prospective and case control studies from Copenhagen City Heart Study. Blood 2004; 104: 3028-3037.
    • (2004) Blood , vol.104 , pp. 3028-3037
    • Frederiksen, J.1    Juul, K.2    Grande, P.3    Jensen, G.B.4    Schroeder, T.V.5    Anne, T.H.6
  • 32
    • 17544392087 scopus 로고    scopus 로고
    • Differences in risk factors, atherosclerosis and cardiovascular disease between ethnic groups in Canada, the study of Health Assessment and Risk in Ethnic Groups (SHARE)
    • Anand S, Yusuf S, Vuksan V, Devaneshan S, Teo K, Montagia A, et al. Differences in risk factors, atherosclerosis and cardiovascular disease between ethnic groups in Canada, the study of Health Assessment and Risk in Ethnic Groups (SHARE). Indian Heart J 2000; 5 (Suppl): S35-S43.
    • (2000) Indian Heart J , vol.5 , Issue.SUPPL.
    • Anand, S.1    Yusuf, S.2    Vuksan, V.3    Devaneshan, S.4    Teo, K.5    Montagia, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.